Promoter scanning of the human COX-2 gene with 8-ring polyamides: unexpected weakening of polyamide-DNA binding and selectivity by replacing an internal N-Me-pyrrole with β-alanine.

Promoter scanning of the human COX-2 gene with 8-ring polyamides: unexpected weakening of polyamide-DNA binding and selectivity by replacing an internal N-Me-pyrrole with β-alanine.

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http://www.wikidata.org/entity/Q43055394
Binding studies of a large antiviral polyamide to a natural HPV sequence.Heterogeneous dynamics in DNA site discrimination by the structurally homologous DNA-binding domains of ETS-family transcription factorsCorrelation of local effects of DNA sequence and position of β-alanine inserts with polyamide-DNA complex binding affinities and kinetics.DNA Binding Polyamides and the Importance of DNA Recognition in their use as Gene-Specific and Antiviral AgentsInteractions of two large antiviral polyamides with the long control region of HPV16.Probing the electrostatics and pharmacological modulation of sequence-specific binding by the DNA-binding domain of the ETS family transcription factor PU.1: a binding affinity and kinetics investigationMapping small DNA ligand hydroxyl radical footprinting and affinity cleavage products for capillary electrophoresisModulation of DNA-polyamide interaction by β-alanine substitutions: a study of positional effects on binding affinity, kinetics and thermodynamics.Sequence-specific DNA alkylation targeting for Kras codon 13 mutation by pyrrole-imidazole polyamide seco-CBI conjugates.β-Alanine and N-terminal cationic substituents affect polyamide-DNA binding.A polyamide inhibits replication of vesicular stomatitis virus by targeting RNA in the nucleocapsid.Selective Targeting of the KRAS Codon 12 Mutation Sequence by Pyrrole-Imidazole Polyamide seco-CBI Conjugates.
P2860

Promoter scanning of the human COX-2 gene with 8-ring polyamides: unexpected weakening of polyamide-DNA binding and selectivity by replacing an internal N-Me-pyrrole with β-alanine.

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http://www.wikidata.org/entity/Q43055394
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2012 nî lūn-bûn
@nan
2012年の論文
@ja
2012年学术文章
@wuu
2012年学术文章
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2012年学术文章
@zh-cn
2012年学术文章
@zh-hans
2012年学术文章
@zh-my
2012年学术文章
@zh-sg
2012年學術文章
@yue
2012年學術文章
@zh-hant
name
Promoter scanning of the human ...... l N-Me-pyrrole with β-alanine.
@en
Promoter scanning of the human ...... l N-Me-pyrrole with β-alanine.
@nl
type
label
Promoter scanning of the human ...... l N-Me-pyrrole with β-alanine.
@en
Promoter scanning of the human ...... l N-Me-pyrrole with β-alanine.
@nl
prefLabel
Promoter scanning of the human ...... l N-Me-pyrrole with β-alanine.
@en
Promoter scanning of the human ...... l N-Me-pyrrole with β-alanine.
@nl
P1433
P1476
P2093
P2860
P304
P31
P356
P433
P478
P50
P577
P5875
P698
P932
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P1433
P1476
Promoter scanning of the human ...... l N-Me-pyrrole with β-alanine.
@en
P2093
P2860
P304
P31
P356
10.1016/J.BIOCHI.2012.09.023
P433
P478
P50
P577
P5875
P698
P932