Reovirus mu2 protein inhibits interferon signaling through a novel mechanism involving nuclear accumulation of interferon regulatory factor 9.
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Potential for Improving Potency and Specificity of Reovirus Oncolysis with Next-Generation Reovirus VariantsApoptosis induction influences reovirus replication and virulence in newborn miceReverse genetics for mammalian reovirus.Serotype-Specific Killing of Large Cell Carcinoma Cells by Reovirus.Proteomic analysis reveals virus-specific Hsp25 modulation in cardiac myocytes.Combining theoretical analysis and experimental data generation reveals IRF9 as a crucial factor for accelerating interferon α-induced early antiviral signalling.Replication of many human viruses is refractory to inhibition by endogenous cellular microRNAs.Gene expression in the brain during reovirus encephalitis.Non-Biased Enrichment Does Not Improve Quantitative Proteomic Delineation of Reovirus T3D-Infected HeLa Cell Protein Alterations.A post-entry step in the mammalian orthoreovirus replication cycle is a determinant of cell tropism.Nonstructural protein NS80 is crucial in recruiting viral components to form aquareoviral factories.Sequence analysis of the genome of piscine orthoreovirus (PRV) associated with heart and skeletal muscle inflammation (HSMI) in Atlantic salmon (Salmo salar).Type I interferon signaling limits reoviral tropism within the brain and prevents lethal systemic infectionCell-type-specific type I interferon antagonism influences organ tropism of murine coronavirusVaricella Viruses Inhibit Interferon-Stimulated JAK-STAT Signaling through Multiple MechanismsA single-amino-acid polymorphism in reovirus protein μ2 determines repression of interferon signaling and modulates myocarditisThe role of type I interferons in intestinal infection, homeostasis, and inflammation.Global Profiling of the Cellular Alternative RNA Splicing Landscape during Virus-Host InteractionsEngineering Recombinant Reoviruses To Display gp41 Membrane-Proximal External-Region Epitopes from HIV-1Identification of functional domains in reovirus replication proteins muNS and mu2.Rotavirus and reovirus modulation of the interferon response.An ITAM in a nonenveloped virus regulates activation of NF-κB, induction of beta interferon, and viral spread.Systems biology unravels interferon responses to respiratory virus infections.HeLa cell response proteome alterations induced by mammalian reovirus T3D infection.Comparative proteomic analyses demonstrate enhanced interferon and STAT-1 activation in reovirus T3D-infected HeLa cells.An improved reverse genetics system for mammalian orthoreovirusesReovirus inhibits interferon production by sequestering IRF3 into viral factories.Dissection of mammalian orthoreovirus µ2 reveals a self-associative domain required for binding to microtubules but not to factory matrix protein µNS.Spontaneous activation of a MAVS-dependent antiviral signaling pathway determines high basal interferon-β expression in cardiac myocytes.A Cytoplasmic RNA Virus Alters the Function of the Cell Splicing Protein SRSF2.Interferon regulatory factor 3 attenuates reovirus myocarditis and contributes to viral clearance.Interplay between Janus Kinase/Signal Transducer and Activator of Transcription Signaling Activated by Type I Interferons and Viral Antagonism.Differential delivery of genomic dsRNA causes reovirus strain-specific differences in IRF3 activation.Tumor Restrictions to Oncolytic Virus.Going (Reo)Viral: Factors Promoting Successful Reoviral Oncolytic InfectionInterferon Regulatory Factor 9 Structure and Regulation
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P2860
Reovirus mu2 protein inhibits interferon signaling through a novel mechanism involving nuclear accumulation of interferon regulatory factor 9.
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name
Reovirus mu2 protein inhibits ...... nterferon regulatory factor 9.
@en
Reovirus mu2 protein inhibits ...... nterferon regulatory factor 9.
@nl
type
label
Reovirus mu2 protein inhibits ...... nterferon regulatory factor 9.
@en
Reovirus mu2 protein inhibits ...... nterferon regulatory factor 9.
@nl
prefLabel
Reovirus mu2 protein inhibits ...... nterferon regulatory factor 9.
@en
Reovirus mu2 protein inhibits ...... nterferon regulatory factor 9.
@nl
P2093
P2860
P356
P1433
P1476
Reovirus mu2 protein inhibits ...... nterferon regulatory factor 9.
@en
P2093
Barbara Sherry
Geoffrey H Holm
Jennifer Zurney
Takeshi Kobayashi
Terence S Dermody
P2860
P304
P356
10.1128/JVI.01787-08
P407
P577
2008-12-24T00:00:00Z