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A unique set of SH3-SH3 interactions controls IB1 homodimerization.Acute hypoglycemia induces retinal cell death in mouseBiological Characterization of Gene Response to Insulin-Induced Hypoglycemia in Mouse RetinaMalonyl-CoA decarboxylase is present in the cytosolic, mitochondrial and peroxisomal compartments of rat hepatocytesMutations in the DNA-binding domain of NR2E3 affect in vivo dimerization and interaction with CRX.Autophagy defect is associated with low glucose-induced apoptosis in 661W photoreceptor cellsInsulin secretion is regulated by the glucose-dependent production of islet beta cell macrophage migration inhibitory factor.Mutations in NR2E3 can cause dominant or recessive retinal degenerations in the same familyHomogeneous and nonradioactive high-throughput screening platform for the characterization of kinase inhibitors in cell lysates.Regulated expression of GLUT2 in diabetes studied in transplanted pancreatic beta cells.Calcium- and proteasome-dependent degradation of the JNK scaffold protein islet-brain 1.Bis-Retinoid A2E Induces an Increase of Basic Fibroblast Growth Factor via Inhibition of Extracellular Signal-Regulated Kinases 1/2 Pathway in Retinal Pigment Epithelium Cells and Facilitates Phagocytosis.A role for hormone-sensitive lipase in glucose-stimulated insulin secretion: a study in hormone-sensitive lipase-deficient mice.Lipoprotein lipase and leptin are accumulated in different secretory compartments in rat adipocytes.Glucose and leptin induce apoptosis in human beta-cells and impair glucose-stimulated insulin secretion through activation of c-Jun N-terminal kinases.Complement factor B polymorphism and the phenotype of early age-related macular degeneration.Saturated fatty acids synergize with elevated glucose to cause pancreatic beta-cell death.A role for the malonyl-CoA/long-chain acyl-CoA pathway of lipid signaling in the regulation of insulin secretion in response to both fuel and nonfuel stimuli.Pancreatic islet adaptation to fasting is dependent on peroxisome proliferator-activated receptor alpha transcriptional up-regulation of fatty acid oxidation.Circadian regulation of islet genes involved in insulin production and secretion.Loss of Extracellular Signal-Regulated Kinase 1/2 in the Retinal Pigment Epithelium Leads to RPE65 Decrease and Retinal Degeneration.ERK1/2 pathway is activated in degenerated Rpe65-deficient mice.Intracellular Stress Signaling Pathways Activated During Human Islet Preparation and Following Acute Cytokine ExposureHypoglycemia and Retinal Cell DeathDcR3/TR6 Effectively Prevents Islet Primary Nonfunction After TransplantationActivation of Malonyl-CoA Decarboxylase in Rat Skeletal Muscle by Contraction and the AMP-activated Protein Kinase Activator 5-Aminoimidazole-4-carboxamide-1-β-d-ribofuranosideGlucagon-like peptide-1 promotes DNA synthesis, activates phosphatidylinositol 3-kinase and increases transcription factor pancreatic and duodenal homeobox gene 1 (PDX-1) DNA binding activity in beta (INS-1)-cellsDexamethasone Induces Posttranslational Degradation of GLUT2 and Inhibition of Insulin Secretion in Isolated Pancreatic β CellsInhibition of glucose-induced insulin secretion by long-term preexposure of pancreatic islets to leptinThe loss of GLUT2 expression in the pancreatic β-cells of diabetic db/db mice is associated with an impaired DNA-binding activity of islet-specific trans-acting factors
P50
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P50
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chercheur
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հետազոտող
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Raphael Roduit
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Raphael Roduit
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Raphael Roduit
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Raphael Roduit
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Raphael Roduit
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Raphael Roduit
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Raphael Roduit
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Raphael Roduit
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Raphael Roduit
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Raphael Roduit
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Raphael Roduit
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Raphael Roduit
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Raphael Roduit
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Raphael Roduit
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Raphael Roduit
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Raphael Roduit
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Raphael Roduit
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Raphael Roduit
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Raphael Roduit
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Raphael Roduit
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Raphael Roduit
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P106
P1153
6601991384
P21
P2798
P31
P496
0000-0001-7440-2799