Design, synthesis, and interaction study of quinazoline-2(1H)-thione derivatives as novel potential Bcl-xL inhibitors.

Design, synthesis, and interaction study of quinazoline-2(1H)-thione derivatives as novel potential Bcl-xL inhibitors.

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http://www.wikidata.org/entity/Q43092357
Research advances at the Institute for Nutritional Sciences at Shanghai, ChinaDesign of Bcl-2 and Bcl-xL Inhibitors with Subnanomolar Binding Affinities Based upon a New ScaffoldA competitive stapled peptide screen identifies a selective small molecule that overcomes MCL-1-dependent leukemia cell survivalJacarelhyperol A induced apoptosis in leukaemia cancer cell through inhibition the activity of Bcl-2 proteins.Development of 3-phenyl-N-(2-(3-phenylureido)ethyl)-thiophene-2-sulfonamide compounds as inhibitors of antiapoptotic Bcl-2 family proteins.Ardisianone, a natural benzoquinone, efficiently induces apoptosis in human hormone-refractory prostate cancers through mitochondrial damage stress and survivin downregulation.A facile, rapid, one-pot regio/stereoselective synthesis of 2-iminothiazolidin-4-ones under solvent/scavenger-free conditions.Organocatalysis in heterocyclic synthesis: DABCO as a mild and efficient catalytic system for the synthesis of a novel class of quinazoline, thiazolo [3,2-a]quinazoline and thiazolo[2,3-b] quinazoline derivatives.Deciphering the crucial molecular properties of a series of Benzothiazole Hydrazone inhibitors that targets anti-apoptotic Bcl-xL protein.FeCl₃∙6H₂O/TMSBr-Catalyzed Rapid Synthesis of Dihydropyrimidinones and Dihydropyrimidinethiones under Microwave Irradiation.Characterization of the stereochemical structures of 2H-thiazolo[3,2-a]pyrimidine compounds and their binding affinities for anti-apoptotic Bcl-2 family proteins.De novo design, synthesis and evaluation of benzylpiperazine derivatives as highly selective binders of Mcl-1.An efficient continuous flow approach to furnish furan-based biaryls
P2860

Design, synthesis, and interaction study of quinazoline-2(1H)-thione derivatives as novel potential Bcl-xL inhibitors.

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http://www.wikidata.org/entity/Q43092357
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2010 nî lūn-bûn
@nan
2010年の論文
@ja
2010年学术文章
@wuu
2010年学术文章
@zh
2010年学术文章
@zh-cn
2010年学术文章
@zh-hans
2010年学术文章
@zh-my
2010年学术文章
@zh-sg
2010年學術文章
@yue
2010年學術文章
@zh-hant
name
Design, synthesis, and interac ...... l potential Bcl-xL inhibitors.
@en
Design, synthesis, and interac ...... l potential Bcl-xL inhibitors.
@nl
type
label
Design, synthesis, and interac ...... l potential Bcl-xL inhibitors.
@en
Design, synthesis, and interac ...... l potential Bcl-xL inhibitors.
@nl
prefLabel
Design, synthesis, and interac ...... l potential Bcl-xL inhibitors.
@en
Design, synthesis, and interac ...... l potential Bcl-xL inhibitors.
@nl
P1433
P1476
P2093
P304
P31
P356
P407
P433
P478
P50
P577
P698
P356
P1433
P1476
Design, synthesis, and interac ...... l potential Bcl-xL inhibitors.
@en
P2093
P304
P31
P356
P407
P433
P478
P50
P577
P698