about
Ligand efficacy and potency at recombinant human MT2 melatonin receptors: evidence for agonist activity of some mt1-antagonistsEfficient transmission and characterization of Creutzfeldt-Jakob disease strains in bank voles.Ultra-efficient PrP(Sc) amplification highlights potentialities and pitfalls of PMCA technologySmall ruminant nor98 prions share biochemical features with human gerstmann-sträussler-scheinker disease and variably protease-sensitive prionopathyIsolation of a Defective Prion Mutant from Natural ScrapieFurther characterisation of transmissible spongiform encephalopathy phenotypes after inoculation of cattle with two temporally separated sources of sheep scrapie from Great BritainA new melatonin receptor ligand with mt1-agonist and MT2-antagonist properties.Intracerebral administration of interleukin-12 (IL-12) and IL-18 modifies the course of mouse scrapiePrion protein amino acid determinants of differential susceptibility and molecular feature of prion strains in mice and volesConversion efficiency of bank vole prion protein in vitro is determined by residues 155 and 170, but does not correlate with the high susceptibility of bank voles to sheep scrapie in vivo.Quantitative profiling of the pathological prion protein allotypes in bank voles by liquid chromatography-mass spectrometry.The bank vole (Myodes glareolus) as a sensitive bioassay for sheep scrapie.Chronic wasting disease in bank voles: characterisation of the shortest incubation time model for prion diseases.Neurochemistry of myenteric plexus neurons of bank vole (Myodes glareolus) ileum.Biochemical characterization of prion strains in bank volesBank Vole Prion Protein As an Apparently Universal Substrate for RT-QuIC-Based Detection and Discrimination of Prion StrainsGerstmann-Sträussler-Scheinker disease subtypes efficiently transmit in bank voles as genuine prion diseases.PrPC Governs Susceptibility to Prion Strains in Bank Vole, While Other Host Factors Modulate Strain Features.A new method for the characterization of strain-specific conformational stability of protease-sensitive and protease-resistant PrPSc.Correlation between infectivity and disease associated prion protein in the nervous system and selected edible tissues of naturally affected scrapie sheep.PRNP genetic variability and molecular typing of natural goat scrapie isolates in a high number of infected flocksMolecular analysis of cases of Italian sheep scrapie and comparison with cases of bovine spongiform encephalopathy (BSE) and experimental BSE in sheepGenetic and Pathological Follow-Up Study of Goats Experimentally and Naturally Exposed to a Sheep Scrapie Isolate.A cationic tetrapyrrole inhibits toxic activities of the cellular prion protein.Prion disease tempo determined by host-dependent substrate reduction.An antipsychotic drug exerts anti-prion effects by altering the localization of the cellular prion protein.Prion Strain Characterization of a Novel Subtype of Creutzfeldt-Jakob Disease.EU-approved rapid tests might underestimate bovine spongiform encephalopathy infection in goats.Protective effect of the AT137RQ and ARQK176 PrP allele against classical scrapie in Sarda breed sheep.PrPSc in salivary glands of scrapie-affected sheep.Transmissibility of Gerstmann-Sträussler-Scheinker syndrome in rodent models: New insights into the molecular underpinnings of prion infectivity.Assessment of the genetic susceptibility of sheep to scrapie by protein misfolding cyclic amplification and comparison with experimental scrapie transmission studies.Molecular discrimination of sheep bovine spongiform encephalopathy from scrapie.L-type bovine spongiform encephalopathy in genetically susceptible and resistant sheep: changes in prion strain or phenotypic plasticity of the disease-associated prion protein?Prion protein alleles showing a protective effect on the susceptibility of sheep to scrapie and bovine spongiform encephalopathyMethods for the evaluation of drug action at the human melatonin receptor subtypes.Early behavioural changes in mice infected with BSE and scrapie: automated home cage monitoring reveals prion strain differences.2-[N-Acylamino(C1-C3)alkyl]indoles as MT1 melatonin receptor partial agonists, antagonists, and putative inverse agonists.Synthesis, pharmacological characterization and QSAR studies on 2-substituted indole melatonin receptor ligands.Co-existence of classical scrapie and Nor98 in a sheep from an Italian outbreak.
P50
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P50
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hulumtues
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researcher
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wetenschapper
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հետազոտող
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Romolo Nonno
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Romolo Nonno
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Romolo Nonno
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Romolo Nonno
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Romolo Nonno
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type
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Romolo Nonno
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Romolo Nonno
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P1053
C-8323-2015
P106
P1153
6602638620
P21
P2798
P31
P3829
P496
0000-0001-7556-1564