Insights into the biology of mobilized hematopoietic stem/progenitor cells through innovative treatment schedules of the CXCR4 antagonist AMD3100.
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Concise Review: CXCR4/CXCL12 Signaling in Immature Hematopoiesis--Lessons From Pharmacological and Genetic ModelsContinuous blockade of CXCR4 results in dramatic mobilization and expansion of hematopoietic stem and progenitor cellsGold Nanoclusters Doped with (64)Cu for CXCR4 Positron Emission Tomography Imaging of Breast Cancer and Metastasis.Modulation of stromal cell-derived factor-1/CXC chemokine receptor 4 axis enhances rhBMP-2-induced ectopic bone formation.Rapid mobilization of hematopoietic progenitors by AMD3100 and catecholamines is mediated by CXCR4-dependent SDF-1 release from bone marrow stromal cells.Effective mobilization of hematopoietic progenitor cells in G-CSF mobilization defective CD26-/- mice through AMD3100-induced disruption of the CXCL12-CXCR4 axis.The ins and outs of hematopoietic stem cells: studies to improve transplantation outcomes.IL-1α and complement cooperate in triggering local neutrophilic inflammation in response to adenovirus and eliminating virus-containing cellsThe haematopoietic stem cell niche at a glance.Proteolytic processing of human serum albumin generates EPI-X4, an endogenous antagonist of CXCR4.CD26 protease inhibition improves functional response of unfractionated cord blood, bone marrow, and mobilized peripheral blood cells to CXCL12/SDF-1.Increased numbers of circulating hematopoietic stem/progenitor cells are chronically maintained in patients treated with the CD49d blocking antibody natalizumab.Hematopoietic stem cell mobilization: updated conceptual renditionsMobilization of hematopoietic stem/progenitor cells: general principles and molecular mechanisms.Suppression of CXCL12 production by bone marrow osteoblasts is a common and critical pathway for cytokine-induced mobilizationThe novel CXCR4 antagonist POL5551 mobilizes hematopoietic stem and progenitor cells with greater efficiency than Plerixafor.Harnessing bone marrow resident regulatory T cells to improve allogeneic stem cell transplant outcomes.Robo4 cooperates with CXCR4 to specify hematopoietic stem cell localization to bone marrow niches.Concurrent blockade of alpha4-integrin and CXCR4 in hematopoietic stem/progenitor cell mobilization.MicroRNA-146a and AMD3100, two ways to control CXCR4 expression in acute myeloid leukemias.Functional consequences of perturbed CXCL12 signal processing: analyses of immature hematopoiesis in GRK6-deficient mice.Effects of CD49d-targeted antisense-oligonucleotide on α4 integrin expression and function of acute lymphoblastic leukemia cells: Results of in vitro and in vivo studies.A Combined In Vivo HSC Transduction/Selection Approach Results in Efficient and Stable Gene Expression in Peripheral Blood Cells in Mice.
P2860
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P2860
Insights into the biology of mobilized hematopoietic stem/progenitor cells through innovative treatment schedules of the CXCR4 antagonist AMD3100.
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2009 nî lūn-bûn
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2009年の論文
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2009年学术文章
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name
Insights into the biology of m ...... the CXCR4 antagonist AMD3100.
@en
Insights into the biology of m ...... the CXCR4 antagonist AMD3100.
@nl
type
label
Insights into the biology of m ...... the CXCR4 antagonist AMD3100.
@en
Insights into the biology of m ...... the CXCR4 antagonist AMD3100.
@nl
prefLabel
Insights into the biology of m ...... the CXCR4 antagonist AMD3100.
@en
Insights into the biology of m ...... the CXCR4 antagonist AMD3100.
@nl
P2093
P2860
P1476
Insights into the biology of m ...... the CXCR4 antagonist AMD3100.
@en
P2093
Doreen Chudziak
Greg Priestley
Thalia Papayannopoulou
P2860
P304
P356
10.1016/J.EXPHEM.2008.10.017
P577
2009-01-20T00:00:00Z