about
Antivascular and antitumor properties of the tubulin-binding chalcone TUB091Genome bioinformatic analysis of nonsynonymous SNPsPyrido[2,1-f]purine-2,4-dione derivatives as a novel class of highly potent human A(3) adenosine receptor antagonists.Identification of [1,2,3]triazolo[4,5-d]pyrimidin-7(6H)-ones as novel inhibitors of Chikungunya virus replication.Synthesis and radical coupling of pyridine-bridged pi-extended tetrathiafulvalene (TTF)-type donors and push-pull analogues.Selective human adenosine A3 antagonists based on pyrido[2,1-f]purine-2,4-diones: novel features of hA3 antagonist binding.Mitochondrial thymidine kinase inhibitors.Thymidine phosphorylase inhibitors: recent developments and potential therapeutic applications.Structure, physiological role, and specific inhibitors of human thymidine kinase 2 (TK2): present and future.Antiviral activity of [1,2,3]triazolo[4,5-d]pyrimidin-7(6H)-ones against chikungunya virus targeting the viral capping nsP1.Synthesis and antiproliferative activity of 6-phenylaminopurines.Microwave-assisted synthesis of C-8 aryl and heteroaryl inosines and determination of their inhibitory activities against Plasmodium falciparum purine nucleoside phosphorylase.Efficient synthesis and anti-enteroviral activity of 9-arylpurines.9-Arylpurines as a novel class of enterovirus inhibitors.Role of histidine-85 in the catalytic mechanism of thymidine phosphorylase as assessed by targeted molecular dynamics simulations and quantum mechanical calculations.Intramolecular cation-pi interactions as the driving force to restrict the conformation of certain nucleosides.The crystal structure of the BAR domain from human Bin1/amphiphysin II and its implications for molecular recognition.Anti-angiogenic activity of a novel multi-substrate analogue inhibitor of thymidine phosphorylase.Towards new thymidine phosphorylase/PD-ECGF inhibitors based on the transition state of the enzyme reaction.Synthesis and evaluation of thymine-derived carboxamides against mitochondrial thymidine kinase (TK-2) and related enzymes.Inhibition of the Replication of Different Strains of Chikungunya Virus by 3-Aryl-[1,2,3]triazolo[4,5-d]pyrimidin-7(6H)-ones.Blocking Blood Flow to Solid Tumors by Destabilizing Tubulin: An Approach to Targeting Tumor Growth.Conformational mimetics of the α-methyl chalcone TUB091 binding tubulin: Design, synthesis and antiproliferative activity.High-affinity ligands of the colchicine domain in tubulin based on a structure-guided design.Novel colchicine-site binders with a cyclohexanedione scaffold identified through a ligand-based virtual screening approach.Identification of a novel 2-oxindole fluorinated derivative as in vivo antitumor agent for prostate cancer acting via AMPK activation.Thymidine phosphorylase is noncompetitively inhibited by 5'-O-trityl-inosine (KIN59) and related compounds.5'-O-Tritylated Nucleoside Derivatives: Inhibition of Thymidine Phosphorylase and Angiogenesis5‘-O-Tritylinosine and Analogues as Allosteric Inhibitors of Human Thymidine PhosphorylaseA New Photoactive and Highly Soluble C60−TTF−C60Dimer: Charge Separation and RecombinationDesign and Synthesis of New 6-Nitro and 6-Amino-3,3a,4,5-Tetrahydro-2H-Benzo[g]indazole Derivatives: Antiproliferative and Antibacterial ActivityChikungunya virus drug discovery: still a long way to go?Diphenyl ether derivatives occupy the expanded binding site of cyclohexanedione compounds at the colchicine site in tubulin by movement of the αT5 loopChalcones and Chalcone-mimetic Derivatives as Notch Inhibitors in a Model of T-cell Acute Lymphoblastic Leukemia
P50
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P50
description
hulumtuese
@sq
researcher
@en
wetenschapper
@nl
հետազոտող
@hy
name
Eva-María Priego
@ast
Eva-María Priego
@en
Eva-María Priego
@es
Eva-María Priego
@nl
Eva-María Priego
@sl
type
label
Eva-María Priego
@ast
Eva-María Priego
@en
Eva-María Priego
@es
Eva-María Priego
@nl
Eva-María Priego
@sl
prefLabel
Eva-María Priego
@ast
Eva-María Priego
@en
Eva-María Priego
@es
Eva-María Priego
@nl
Eva-María Priego
@sl
P1053
L-1688-2014
P106
P1153
6602350466
P21
P31
P3829
P496
0000-0001-9470-4508