Rapid optimization of a peptide inhibitor of malaria parasite invasion by comprehensive N-methyl scanning. - Wikidata - awgldk - TriplyDB

Rapid optimization of a peptide inhibitor of malaria parasite invasion by comprehensive N-methyl scanning.

Rapid optimization of a peptide inhibitor of malaria parasite invasion by comprehensive N-methyl scanning.

http://www.wikidata.org/entity/Q43148430

about

Mechanisms of cellular invasion by intracellular parasites Revealing the sequence and resulting cellular morphology of receptor-ligand interactions during Plasmodium falciparum invasion of erythrocytes Structural and Functional Insights into the Malaria Parasite Moving Junction Complex Host-parasite interaction: multiple sites in the Plasmodium vivax tryptophan-rich antigen PvTRAg38 interact with the erythrocyte receptor band 3 New targets for drug discovery against malaria Molecular insights into the interaction between Plasmodium falciparum apical membrane antigen 1 and an invasion-inhibitory peptide AMA1 and MAEBL are important for Plasmodium falciparum sporozoite infection of the liver Peptide inhibitors of the malaria surface protein, apical membrane antigen 1: identification of key binding residues Interaction between Plasmodium falciparum apical membrane antigen 1 and the rhoptry neck protein complex defines a key step in the erythrocyte invasion process of malaria parasites.Synthesis of chemically modified bioactive peptides: recent advances, challenges and developments for medicinal chemistry.Increasing αvβ3 selectivity of the anti-angiogenic drug cilengitide by N-methylation.Juxtamembrane shedding of Plasmodium falciparum AMA1 is sequence independent and essential, and helps evade invasion-inhibitory antibodies Identification and localization of minimal MHC-restricted CD8+ T cell epitopes within the Plasmodium falciparum AMA1 protein Novel analogues of the therapeutic complement inhibitor compstatin with significantly improved affinity and potency.Peptide Inhibition of Topoisomerase IB from Plasmodium falciparum.Computational and biophysical approaches to protein-protein interaction inhibition of Plasmodium falciparum AMA1/RON2 complex.Stability of the Plasmodium falciparum AMA1-RON2 Complex Is Governed by the Domain II (DII) Loop Surface plasmon resonance for vaccine design and efficacy studies: recent applications and future trends.Novel antimalarial drug targets: hope for new antimalarial drugs.Screening for small molecule inhibitors of Toxoplasma gondii.Collagen IV-derived peptide binds hydrophobic cavity of Legionella pneumophila Mip and interferes with bacterial epithelial transmigration.Solution NMR characterization of apical membrane antigen 1 and small molecule interactions as a basis for designing new antimalarials.Heterologous expression of Plasmodium vivax apical membrane antigen 1 (PvAMA1) for binding peptide selection.Efficient backbone cyclization of linear peptides by a recombinant asparaginyl endopeptidase.Enantioselective direct α-amination of aldehydes via a photoredox mechanism: a strategy for asymmetric amine fragment coupling.Survey of the 2009 commercial optical biosensor literature.Engineering an Affinity-Enhanced Peptide through Optimization of Cyclization Chemistry.The influence of solvent on conformational properties of peptides with Aib residue-a DFT study.The cysteine-rich regions of Plasmodium falciparum RON2 bind with host erythrocyte and AMA1 during merozoite invasion.Metabolic stability of peptidomimetics: N-methyl and aza heptapeptide analogs of a PKB/Akt inhibitor.Antimalarial drug discovery targeting apical membrane antigen 1 The effect of N-methylation on transition state mimetic inhibitors of the Plasmodium protease, plasmepsin V A critical evaluation of pyrrolo[2,3-d]pyrimidine-4-amines as Plasmodium falciparum apical membrane antigen 1 (AMA1) inhibitors

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Rapid optimization of a peptide inhibitor of malaria parasite invasion by comprehensive N-methyl scanning.

http://www.wikidata.org/entity/Q43148430

description

2009 nî lūn-bûn

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2009年の論文

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2009年学术文章

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2009年学术文章

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2009年学术文章

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2009年学术文章

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2009年学术文章

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2009年学术文章

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2009年學術文章

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2009年學術文章

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name

Rapid optimization of a peptid ...... mprehensive N-methyl scanning.

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Rapid optimization of a peptid ...... mprehensive N-methyl scanning.

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Rapid optimization of a peptid ...... mprehensive N-methyl scanning.

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Rapid optimization of a peptid ...... mprehensive N-methyl scanning.

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Rapid optimization of a peptid ...... mprehensive N-methyl scanning.

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Rapid optimization of a peptid ...... mprehensive N-methyl scanning.

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Andrew B Hughes

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Andrew M Coley

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Denis Scanlon

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Jennifer K Sabo

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Joanne L Casey

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John A Karas

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Karen S Harris

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Michael Foley

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Olan Dolezal

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Raymond S Norton

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P2860

The crystal structure of a GroEL/peptide complex: plasticity as a basis for substrate diversity

Refined crystal structure of the influenza virus N9 neuraminidase-NC41 Fab complex

Structure of the Malaria Antigen AMA1 in Complex with a Growth-Inhibitory Antibody

Protein NMR structure determination with automated NOE assignment using the new software CANDID and the torsion angle dynamics algorithm DYANA

The Xplor-NIH NMR molecular structure determination package

Gradient-tailored excitation for single-quantum NMR spectroscopy of aqueous solutions

MOLMOL: a program for display and analysis of macromolecular structures

The program XEASY for computer-supported NMR spectral analysis of biological macromolecules

A role for apical membrane antigen 1 during invasion of hepatocytes by Plasmodium falciparum sporozoites

Human malaria parasites in continuous culture

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