Assessing drug distribution in tissues expressing P-glycoprotein through physiologically based pharmacokinetic modeling: model structure and parameters determination.
about
Relating tissue/organ energy expenditure to metabolic fluxes in mouse and human: experimental data integrated with mathematical modelingChallenges of using in vitro data for modeling P-glycoprotein efflux in the blood-brain barrier.Incorporation of ABCB1-mediated transport into a physiologically-based pharmacokinetic model of docetaxel in mice.Physiologically based pharmacokinetic modelling of drug penetration across the blood-brain barrier--towards a mechanistic IVIVE-based approachA mechanistic framework for in vitro-in vivo extrapolation of liver membrane transporters: prediction of drug-drug interaction between rosuvastatin and cyclosporineRole of membrane transporters in the safety profile of drugs.Development of a physiologically-based pharmacokinetic model of the rat central nervous system.Strategies to minimize CNS toxicity: in vitro high-throughput assays and computational modeling.Time- and passage-dependent characteristics of a Calu-3 respiratory epithelial cell model.Physiologically based pharmacokinetic modelling of high- and low-dose etoposide: from adults to children.
P2860
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P2860
Assessing drug distribution in tissues expressing P-glycoprotein through physiologically based pharmacokinetic modeling: model structure and parameters determination.
description
2009 nî lūn-bûn
@nan
2009年の論文
@ja
2009年学术文章
@wuu
2009年学术文章
@zh
2009年学术文章
@zh-cn
2009年学术文章
@zh-hans
2009年学术文章
@zh-my
2009年学术文章
@zh-sg
2009年學術文章
@yue
2009年學術文章
@zh-hant
name
Assessing drug distribution in ...... and parameters determination.
@en
Assessing drug distribution in ...... and parameters determination.
@nl
type
label
Assessing drug distribution in ...... and parameters determination.
@en
Assessing drug distribution in ...... and parameters determination.
@nl
prefLabel
Assessing drug distribution in ...... and parameters determination.
@en
Assessing drug distribution in ...... and parameters determination.
@nl
P2093
P2860
P356
P1476
Assessing drug distribution in ...... and parameters determination.
@en
P2093
Fahima Nekka
Frédérique Fenneteau
Jacques Turgeon
Lucie Couture
Véronique Michaud
P2860
P2888
P356
10.1186/1742-4682-6-2
P577
2009-01-15T00:00:00Z
P5875
P6179
1036118994