Structural basis for inhibition of the Tob-CNOT7 interaction by a fragment screening approach.

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Structural basis for inhibition of the Tob-CNOT7 interaction by a fragment screening approach.

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2015 nî lūn-bûn

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2015年の論文

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2015年学术文章

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2015年学术文章

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2015年学术文章

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Structural basis for inhibitio ...... a fragment screening approach.

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Structural basis for inhibitio ...... a fragment screening approach.

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Structural basis for inhibitio ...... a fragment screening approach.

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Structural basis for inhibitio ...... a fragment screening approach.

@en

Structural basis for inhibitio ...... a fragment screening approach.

@en-gb

Structural basis for inhibitio ...... a fragment screening approach.

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Structural basis for inhibitio ...... a fragment screening approach.

@en

Structural basis for inhibitio ...... a fragment screening approach.

@en-gb

Structural basis for inhibitio ...... a fragment screening approach.

@nl

P1476

Structural basis for inhibitio ...... a fragment screening approach.

@en

P2093

Dongke Yan

http://www.w3.org/2001/XMLSchema#string

Kouhei Tsumoto

http://www.w3.org/2001/XMLSchema#string

Ruihua Liu

http://www.w3.org/2001/XMLSchema#string

Shinya Tashiro

http://www.w3.org/2001/XMLSchema#string

Tadashi Yamamoto

http://www.w3.org/2001/XMLSchema#string

Toru Suzuki

http://www.w3.org/2001/XMLSchema#string

Yuwei Bai

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P2860

The anti-proliferative activity of BTG/TOB proteins is mediated via the Caf1a (CNOT7) and Caf1b (CNOT8) deadenylase subunits of the Ccr4-not complex

Structural basis for the antiproliferative activity of the Tob-hCaf1 complex

Human TOB, an antiproliferative transcription factor, is a poly(A)-binding protein-dependent positive regulator of cytoplasmic mRNA deadenylation

Crystal structures of human BTG2 and mouse TIS21 involved in suppression of CAF1 deadenylase activity

Alteration of expression or phosphorylation status of tob, a novel tumor suppressor gene product, is an early event in lung cancer

In search of a function for the TIS21/PC3/BTG1/TOB family

The mammalian anti-proliferative BTG/Tob protein family

Molecular complexity and its impact on the probability of finding leads for drug discovery.

Biophysical methods for identifying fragment-based inhibitors of protein-protein interactions.

Evidence providing new insights into TOB-promoted deadenylation and supporting a link between TOB's deadenylation-enhancing and antiproliferative activities.

P2888

s13238-015-0225-6

P304

924-928

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P31

scholarly article

P356

10.1007/S13238-015-0225-6

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P433

http://www.w3.org/2001/XMLSchema#string

P478

http://www.w3.org/2001/XMLSchema#string

P50

Mark Bartlam

Satoru Nagatoishi

P577

2015-10-30T00:00:00Z

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P5875

283449077

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P698

26518565

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4656213

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