about
Posttranscriptional control of T cell effector function by aerobic glycolysisBiology of recently discovered cytokines: discerning the pro- and anti-inflammatory properties of interleukin-27Duration of antigen receptor signaling determines T-cell tolerance or activation.A mouse model of HIES reveals pro- and anti-inflammatory functions of STAT3.Extraordinary effects of unnatural pairingsCutting edge: the Th1 response inhibits the generation of peripheral regulatory T cells.An activating NLRC4 inflammasome mutation causes autoinflammation with recurrent macrophage activation syndromeHelper T cell IL-2 production is limited by negative feedback and STAT-dependent cytokine signals.Transcriptional and epigenetic networks of helper T and innate lymphoid cells.Mechanisms of Jak/STAT signaling in immunity and diseaseThe role of IL-27 in the development of T-cell responses during parasitic infections.IL-27 shakes up the establishment of ectopic lymphoid structures.Role of IL-17 and regulatory T lymphocytes in a systemic autoimmune disease.Induction of cytotoxic T lymphocyte antigen 4 (CTLA-4) restricts clonal expansion of helper T cells.Distinct requirements for T-bet in gut innate lymphoid cellsAn autoregulatory enhancer controls mammary-specific STAT5 functions.T cell activation induces proteasomal degradation of Argonaute and rapid remodeling of the microRNA repertoire.Signal transducer and activator of transcription 5 (STAT5) paralog dose governs T cell effector and regulatory functions.IL-13-producing Th1 and Th17 cells characterize adaptive responses to both self and foreign antigens.The JAK-STAT pathway: impact on human disease and therapeutic interventionMechanisms and consequences of Jak-STAT signaling in the immune system.BACH2 immunodeficiency illustrates an association between super-enhancers and haploinsufficiency.Asymmetric Action of STAT Transcription Factors Drives Transcriptional Outputs and Cytokine Specificity.Subset- and tissue-defined STAT5 thresholds control homeostasis and function of innate lymphoid cellsIL-27 limits IL-2 production during Th1 differentiation.Characterization of a candidate Trypanosoma brucei U1 small nuclear RNA gene.Group 1 Innate Lymphoid Cell Lineage Identity Is Determined by a cis-Regulatory Element Marked by a Long Non-coding RNA.STAT5B: A Differential Regulator of the Life and Death of CD4+ Effector Memory T Cells.The IL-27R (WSX-1) is required to suppress T cell hyperactivity during infection.JAK inhibition as a therapeutic strategy for immune and inflammatory diseases.Cutting edge: early IL-4 production governs the requirement for IL-27-WSX-1 signaling in the development of protective Th1 cytokine responses following Leishmania major infection.Cell cycle controlling the silencing and functioning of mammalian activators.Role of T-bet in commitment of TH1 cells before IL-12-dependent selection.Positive and negative regulation of the IL-27 receptor during lymphoid cell activation.TLR ligands can activate dendritic cells to provide a MyD88-dependent negative signal for Th2 cell development.Non-classical Immunity Controls Microbiota Impact on Skin Immunity and Tissue RepairIL-27R deficiency delays the onset of colitis and protects from helminth-induced pathology in a model of chronic IBDInterleukin 27 negatively regulates the development of interleukin 17-producing T helper cells during chronic inflammation of the central nervous systemThe IL-27 receptor (WSX-1) is an inhibitor of innate and adaptive elements of type 2 immunityInhibition of IL-2 responsiveness by IL-6 is required for the generation of GC-TFH cells
P50
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P50
description
hulumtues
@sq
researcher
@en
wetenschapper
@nl
հետազոտող
@hy
name
Alejandro Villarino
@ast
Alejandro Villarino
@en
Alejandro Villarino
@es
Alejandro Villarino
@nl
type
label
Alejandro Villarino
@ast
Alejandro Villarino
@en
Alejandro Villarino
@es
Alejandro Villarino
@nl
prefLabel
Alejandro Villarino
@ast
Alejandro Villarino
@en
Alejandro Villarino
@es
Alejandro Villarino
@nl
P106
P1153
6602705734
P21
P31
P496
0000-0001-8068-2176