Clearance of Rhodopsin(P23H) aggregates requires the ERAD effector VCP.
about
The delicate balance between secreted protein folding and endoplasmic reticulum-associated degradation in human physiologyInactivation of VCP/ter94 suppresses retinal pathology caused by misfolded rhodopsin in DrosophilaValosin-containing protein regulates the proteasome-mediated degradation of DNA-PKcs in glioma cells.Chemical chaperone 4-phenylbutyrate prevents endoplasmic reticulum stress induced by T17M rhodopsin.Endoplasmic reticulum stress-associated cone photoreceptor degeneration in cyclic nucleotide-gated channel deficiency.M-opsin protein degradation is inhibited by MG-132 in Rpe65⁻/⁻ retinal explant cultureAn S-opsin knock-in mouse (F81Y) reveals a role for the native ligand 11-cis-retinal in cone opsin biosynthesisGenome-wide RNAi screen identifies SEC61A and VCP as conserved regulators of Sindbis virus entry.Neuroprotective Strategy in Retinal Degeneration: Suppressing ER Stress-Induced Cell Death via Inhibition of the mTOR Signal.Endoplasmic reticulum-associated degradation (ERAD) of misfolded glycoproteins and mutant P23H rhodopsin in photoreceptor cells.Gene therapy in animal models of autosomal dominant retinitis pigmentosaThe cell stress machinery and retinal degeneration.Targeting the Proteostasis Network in Rhodopsin Retinitis Pigmentosa.The co-chaperone and reductase ERdj5 facilitates rod opsin biogenesis and quality control.BiP prevents rod opsin aggregation.Wild-type opsin does not aggregate with a misfolded opsin mutant.Can fly photoreceptors lead to treatments for rho ((P23H)) -linked retinitis pigmentosa?The molecular and cellular basis of rhodopsin retinitis pigmentosa reveals potential strategies for therapy.The role of the ER stress-response protein PERK in rhodopsin retinitis pigmentosa.Expression of p97/VCP and ubiquitin during postnatal development of the degenerating rat retina.Dominant and recessive mutations in rhodopsin activate different cell death pathways.
P2860
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P2860
Clearance of Rhodopsin(P23H) aggregates requires the ERAD effector VCP.
description
2010 nî lūn-bûn
@nan
2010年の論文
@ja
2010年学术文章
@wuu
2010年学术文章
@zh
2010年学术文章
@zh-cn
2010年学术文章
@zh-hans
2010年学术文章
@zh-my
2010年学术文章
@zh-sg
2010年學術文章
@yue
2010年學術文章
@zh-hant
name
Clearance of Rhodopsin
@nl
Clearance of Rhodopsin(P23H) aggregates requires the ERAD effector VCP.
@en
type
label
Clearance of Rhodopsin
@nl
Clearance of Rhodopsin(P23H) aggregates requires the ERAD effector VCP.
@en
prefLabel
Clearance of Rhodopsin
@nl
Clearance of Rhodopsin(P23H) aggregates requires the ERAD effector VCP.
@en
P2093
P1476
Clearance of Rhodopsin(P23H) aggregates requires the ERAD effector VCP.
@en
P2093
Ana Griciuc
Liviu Aron
Marius Ueffing
P304
P356
10.1016/J.BBAMCR.2010.01.008
P577
2010-01-25T00:00:00Z