Phenotypic and enzymatic comparative analysis of the novel KPC variant KPC-5 and its evolutionary variants, KPC-2 and KPC-4. - Wikidata - awgldk - TriplyDB

Phenotypic and enzymatic comparative analysis of the novel KPC variant KPC-5 and its evolutionary variants, KPC-2 and KPC-4.

Phenotypic and enzymatic comparative analysis of the novel KPC variant KPC-5 and its evolutionary variants, KPC-2 and KPC-4.

http://www.wikidata.org/entity/Q43194393

about

"Stormy waters ahead": global emergence of carbapenemases Global Dissemination of Carbapenemase-Producing Klebsiella pneumoniae: Epidemiology, Genetic Context, Treatment Options, and Detection Methods Carbapenemase-producing Klebsiella pneumoniae: molecular and genetic decoding Crystal Structures of KPC-2 -Lactamase in Complex with 3-Nitrophenyl Boronic Acid and the Penam Sulfone PSR-3-226 A structural, epidemiological & genetic overview of Klebsiella pneumoniae carbapenemases (KPCs)Natural Variants of the KPC-2 Carbapenemase have Evolved Increased Catalytic Efficiency for Ceftazidime Hydrolysis at the Cost of Enzyme Stability Emergence of KPC-producing Klebsiella pneumoniae in Italy.Detection of KPC in Acinetobacter spp. in Puerto Rico.Evaluation of a commercial microarray system for detection of SHV-, TEM-, CTX-M-, and KPC-type beta-lactamase genes in Gram-negative isolates.Detection and treatment options for Klebsiella pneumoniae carbapenemases (KPCs): an emerging cause of multidrug-resistant infection.Functional cloning and characterization of antibiotic resistance genes from the chicken gut microbiome.Emerging rapid resistance testing methods for clinical microbiology laboratories and their potential impact on patient management.Multiplex real-time PCR assay for detection and classification of Klebsiella pneumoniae carbapenemase gene (bla KPC) variants Novel genetic environment of the plasmid-mediated KPC-3 gene detected in Escherichia coli and Citrobacter freundii isolates from China.Pseudomonas aeruginosa: resistance to the max Phenotypic and enzymatic comparative analysis of the KPC variants, KPC-2 and its recently discovered variant KPC-15.Partial excision of blaKPC from Tn4401 in carbapenem-resistant Klebsiella pneumoniae Worldwide diversity of Klebsiella pneumoniae that produce beta-lactamase blaKPC-2 gene.Role of ISKpn7 and deletions in blaKPC gene expression.KPC-9, a novel carbapenemase from clinical specimens in Israel Direct detection and genotyping of Klebsiella pneumoniae carbapenemases from urine by use of a new DNA microarray test.KPC-4 Is encoded within a truncated Tn4401 in an IncL/M plasmid, pNE1280, isolated from Enterobacter cloacae and Serratia marcescens.Complete nucleotide sequences of blaKPC-4- and blaKPC-5-harboring IncN and IncX plasmids from Klebsiella pneumoniae strains isolated in New Jersey.Surveillance of carbapenem-resistant Pseudomonas aeruginosa isolates from Puerto Rican Medical Center Hospitals: dissemination of KPC and IMP-18 beta-lactamases Clinical outcomes of patients with Klebsiella pneumoniae carbapenemase-producing K. pneumoniae after treatment with imipenem or meropenem.Beta-lactamases identified in clinical isolates of Pseudomonas aeruginosa.Status report on carbapenemases: challenges and prospects.Klebsiella pneumoniae carbapenemase (KPC)-producing Klebsiella pneumoniae: a review of epidemiological and clinical aspects.Wide dissemination of Pseudomonas aeruginosa producing beta-lactamase blaKPC-2 gene in Colombia.Functional characterization of Tn4401, a Tn3-based transposon involved in blaKPC gene mobilization.In Vitro Selection of Meropenem Resistance among Ceftazidime-Avibactam-Resistant, Meropenem-Susceptible Klebsiella pneumoniae Isolates with Variant KPC-3 Carbapenemases.Emergence of Ceftazidime-Avibactam Resistance Due to Plasmid-Borne blaKPC-3 Mutations during Treatment of Carbapenem-Resistant Klebsiella pneumoniae Infections The epidemiology of carbapenemases in Latin America and the Caribbean.Engineering Specificity from Broad to Narrow: Design of a β-Lactamase Inhibitory Protein (BLIP) Variant That Exclusively Binds and Detects KPC β-Lactamase.Antibiotic resistance and substrate profiles of the class A carbapenemase KPC-6 bla(KPC) RNA expression correlates with two transcriptional start sites but not always with gene copy number in four genera of Gram-negative pathogens In vitro activity of the {beta}-lactamase inhibitor NXL104 against KPC-2 carbapenemase and Enterobacteriaceae expressing KPC carbapenemases.Mutations in blaKPC-3 That Confer Ceftazidime-Avibactam Resistance Encode Novel KPC-3 Variants That Function as Extended-Spectrum β-Lactamases Overview of the epidemiology and the threat of Klebsiella pneumoniae carbapenemases (KPC) resistance.Rapid identification of bla KPC-possessing Enterobacteriaceae by PCR/electrospray ionization-mass spectrometry.

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Phenotypic and enzymatic comparative analysis of the novel KPC variant KPC-5 and its evolutionary variants, KPC-2 and KPC-4.

http://www.wikidata.org/entity/Q43194393

description

2008 nî lūn-bûn

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2008年の論文

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2008年学术文章

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2008年学术文章

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2008年学术文章

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2008年学术文章

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2008年学术文章

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2008年学术文章

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2008年學術文章

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2008年學術文章

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name

Phenotypic and enzymatic compa ...... ary variants, KPC-2 and KPC-4.

@en

Phenotypic and enzymatic compa ...... ary variants, KPC-2 and KPC-4.

@nl

type

label

Phenotypic and enzymatic compa ...... ary variants, KPC-2 and KPC-4.

@en

Phenotypic and enzymatic compa ...... ary variants, KPC-2 and KPC-4.

@nl

prefLabel

Phenotypic and enzymatic compa ...... ary variants, KPC-2 and KPC-4.

@en

Phenotypic and enzymatic compa ...... ary variants, KPC-2 and KPC-4.

@nl

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Antimicrobial Agents and Chemotherapy

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Phenotypic and enzymatic compa ...... ary variants, KPC-2 and KPC-4.

@en

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Daniel J Wolter

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Marie-France I Palepou

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Nancy D Hanson

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Philip M Kurpiel

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P2860

Novel carbapenem-hydrolyzing beta-lactamase, KPC-1, from a carbapenem-resistant strain of Klebsiella pneumoniae

Extended-spectrum beta-lactamases in the 21st century: characterization, epidemiology, and detection of this important resistance threat

Carbapenemases: the versatile beta-lactamases

Insertion sequences

Transposons Tn1696 and Tn21 and their integrons In4 and In2 have independent origins.

Carbapenem-resistant strain of Klebsiella oxytoca harboring carbapenem-hydrolyzing beta-lactamase KPC-2.

Amino acid substitutions at Ambler position Gly238 in the SHV-1 beta-lactamase: exploring sequence requirements for resistance to penicillins and cephalosporins.

Outbreak of Klebsiella pneumoniae producing a new carbapenem-hydrolyzing class A beta-lactamase, KPC-3, in a New York Medical Center.

Imipenem resistance in a Salmonella clinical strain due to plasmid-mediated class A carbapenemase KPC-2.

First detection of the plasmid-mediated class A carbapenemase KPC-2 in clinical isolates of Klebsiella pneumoniae from South America.

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557-562

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scholarly article

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10.1128/AAC.00734-08

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2

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53

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Richard Goering

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2008-11-17T00:00:00Z

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19015357

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2630594

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