Small molecule beta-amyloid inhibitors that stabilize protofibrillar structures in vitro improve cognition and pathology in a mouse model of Alzheimer's disease.

Small molecule beta-amyloid inhibitors that stabilize protofibrillar structures in vitro improve cognition and pathology in a mouse model of Alzheimer's disease.

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http://www.wikidata.org/entity/Q43194548
Sodium/myo-Inositol transporters: substrate transport requirements and regional brain expression in the TgCRND8 mouse model of amyloid pathologyOral Triphenylmethane Food Dye Analog, Brilliant Blue G, Prevents Neuronal Loss in APPSwDI/NOS2-/- Mouse Model.Protection against the synaptic targeting and toxicity of Alzheimer's-associated Aβ oligomers by insulin mimetic chiro-inositols.Abeta42 neurotoxicity is mediated by ongoing nucleated polymerization process rather than by discrete Abeta42 species.Role of cerebrospinal fluid biomarkers in clinical trials for Alzheimer's disease modifying therapiesA cell factory of Bacillus subtilis engineered for the simple bioconversion of myo-inositol to scyllo-inositol, a potential therapeutic agent for Alzheimer's diseaseDrug development for Alzheimer's disease: recent progressAnti-amyloidogenic properties of some phenolic compoundsDiscovery and structure activity relationship of small molecule inhibitors of toxic β-amyloid-42 fibril formationTrue and apparent inhibition of amyloid fibril formation.The "Other" Inositols and Their Phosphates: Synthesis, Biology, and Medicine (with Recent Advances in myo-Inositol Chemistry).Biochemistry of amyloid β-protein and amyloid deposits in Alzheimer disease.Inhibition of amyloid oligomerization into different supramolecular architectures by small molecules: mechanistic insights and design rules.Aβ(1-42) assembly in the presence of scyllo-inositol derivatives: identification of an oxime linkage as important for the development of assembly inhibitors.
P2860

Small molecule beta-amyloid inhibitors that stabilize protofibrillar structures in vitro improve cognition and pathology in a mouse model of Alzheimer's disease.

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http://www.wikidata.org/entity/Q43194548
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2010 nî lūn-bûn
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2010年の論文
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2010年学术文章
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name
Small molecule beta-amyloid in ...... model of Alzheimer's disease.
@en
Small molecule beta-amyloid in ...... model of Alzheimer's disease.
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type
label
Small molecule beta-amyloid in ...... model of Alzheimer's disease.
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Small molecule beta-amyloid in ...... model of Alzheimer's disease.
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Small molecule beta-amyloid in ...... model of Alzheimer's disease.
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Small molecule beta-amyloid in ...... model of Alzheimer's disease.
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Small molecule beta-amyloid in ...... e model of Alzheimer's disease
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P2860
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10.1111/J.1460-9568.2009.07052.X
P407
P433
P478
P50
P577
P698
P921