Walkmycin B targets WalK (YycG), a histidine kinase essential for bacterial cell growth. - Wikidata - awgldk - TriplyDB

Walkmycin B targets WalK (YycG), a histidine kinase essential for bacterial cell growth.

Walkmycin B targets WalK (YycG), a histidine kinase essential for bacterial cell growth.

http://www.wikidata.org/entity/Q43199652

about

Biologically inspired strategies for combating bacterial biofilms Evolution of multidrug resistance during Staphylococcus aureus infection involves mutation of the essential two component regulator WalKR A biochemical characterization of the DNA binding activity of the response regulator VicR from Streptococcus mutans NH125 kills methicillin-resistant Staphylococcus aureus persisters by lipid bilayer disruption.Efficacy of novel antibacterial compounds targeting histidine kinase YycG protein.Thiazolidione derivatives targeting the histidine kinase YycG are effective against both planktonic and biofilm-associated Staphylococcus epidermidis.Peptidoglycan crosslinking relaxation plays an important role in Staphylococcus aureus WalKR-dependent cell viability.Small-molecule inhibition of bacterial two-component systems to combat antibiotic resistance and virulence.Antibacterial and anti-biofilm activities of thiazolidione derivatives against clinical staphylococcus strains.Putative histidine kinase inhibitors with antibacterial effect against multi-drug resistant clinical isolates identified by in vitro and in silico screens.Anti-bacterial and Anti-biofilm Evaluation of Thiazolopyrimidinone Derivatives Targeting the Histidine Kinase YycG Protein of Staphylococcus epidermidis.Viable screening targets related to the bacterial cell wall.Virulence factor targeting of the bacterial pathogen Staphylococcus aureus for vaccine and therapeutics.Bacterial signal transduction networks via connectors and development of the inhibitors as alternative antibiotics.Isolation and characterization of signermycin B, an antibiotic that targets the dimerization domain of histidine kinase WalK Development of an antivirulence drug against Streptococcus mutans: repression of biofilm formation, acid tolerance, and competence by a histidine kinase inhibitor, walkmycin C Two-Component Signal Transduction Systems of Pathogenic Bacteria As Targets for Antimicrobial Therapy: An Overview.Waldiomycin, a novel WalK-histidine kinase inhibitor from Streptomyces sp. MK844-mF10.Angucycline antibiotic waldiomycin recognizes common structural motif conserved in bacterial histidine kinases.Evidence of Cross-Regulation in Two Closely Related Pyruvate-Sensing Systems in Uropathogenic Escherichia coli.Essential Two-Component Systems Regulating Cell Envelope Functions: Opportunities for Novel Antibiotic Therapies.The two-component signaling system VraSRSS is critical for multidrug resistance and full virulence in Streptococcus suis serotype 2.Screening for inhibitors of mutacin synthesis in Streptococcus mutans using fluorescent reporter strains.as a Prominent Resource of Future Anti-MRSA Drugs

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P2860

Walkmycin B targets WalK (YycG), a histidine kinase essential for bacterial cell growth.

http://www.wikidata.org/entity/Q43199652

description

2010 nî lūn-bûn

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2010年の論文

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2010年学术文章

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2010年学术文章

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2010年学术文章

@zh-cn

2010年学术文章

@zh-hans

2010年学术文章

@zh-my

2010年学术文章

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2010年學術文章

@yue

2010年學術文章

@zh-hant

name

Walkmycin B targets WalK (YycG), a histidine kinase essential for bacterial cell growth.

@en

Walkmycin B targets WalK (YycG), a histidine kinase essential for bacterial cell growth.

@nl

type

label

Walkmycin B targets WalK (YycG), a histidine kinase essential for bacterial cell growth.

@en

Walkmycin B targets WalK (YycG), a histidine kinase essential for bacterial cell growth.

@nl

prefLabel

Walkmycin B targets WalK (YycG), a histidine kinase essential for bacterial cell growth.

@en

Walkmycin B targets WalK (YycG), a histidine kinase essential for bacterial cell growth.

@nl

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P1433

The Journal of Antibiotics

P1476

Walkmycin B targets WalK (YycG), a histidine kinase essential for bacterial cell growth

@en

P2093

Aaron Martin

http://www.w3.org/2001/XMLSchema#string

Akihiro Doi

http://www.w3.org/2001/XMLSchema#string

Ario Okada

http://www.w3.org/2001/XMLSchema#string

John Quinn

http://www.w3.org/2001/XMLSchema#string

Kunio Inoue

http://www.w3.org/2001/XMLSchema#string

Masayuki Igarashi

http://www.w3.org/2001/XMLSchema#string

Maya Umekita

http://www.w3.org/2001/XMLSchema#string

Naoko Kinoshita

http://www.w3.org/2001/XMLSchema#string

Ryutaro Utsumi

http://www.w3.org/2001/XMLSchema#string

Takafumi Watanabe

http://www.w3.org/2001/XMLSchema#string

P2860

The essential two-component regulatory system encoded by yycF and yycG modulates expression of the ftsAZ operon in Bacillus subtilis

Inhibitors of bacterial two-component signalling systems.

Two-component signal transduction in Enterococcus faecalis.

Histidine kinases as targets for new antimicrobial agents.

New insights into the WalK/WalR (YycG/YycF) essential signal transduction pathway reveal a major role in controlling cell wall metabolism and biofilm formation in Staphylococcus aureus

A matter of life and death: cell wall homeostasis and the WalKR (YycGF) essential signal transduction pathway.

Antibacterial agents that inhibit histidine protein kinase YycG of Bacillus subtilis.

A genomic analysis of two-component signal transduction in Streptococcus pneumoniae.

Domain organization and molecular characterization of 13 two-component systems identified by genome sequencing of Streptococcus pneumoniae.

P2888

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89-94

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scholarly article

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10.1038/JA.2009.128

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2

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63

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Toshihide Okajima

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2010-01-08T00:00:00Z

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40895406

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20057515

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