Use of NMR metabolomics to analyze the targets of D-cycloserine in mycobacteria: role of D-alanine racemase.
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Potential of metabolomics to reveal Burkholderia cepacia complex pathogenesis and antibiotic resistanceFrom screen to target: insights and approaches for the development of anti-virulence compoundsStructure of the Mycobacterium tuberculosis D-Alanine:D-Alanine Ligase, a Target of the Antituberculosis Drug D-CycloserineKinetic mechanism and inhibition of Mycobacterium tuberculosis D-alanine:D-alanine ligase by the antibiotic D-cycloserineA point mutation in cycA partially contributes to the D-cycloserine resistance trait of Mycobacterium bovis BCG vaccine strainsEmerging Approaches to Tuberculosis Drug Development: At Home in the Metabolome.Advances in Nuclear Magnetic Resonance for Drug Discovery.Analysis of metabolomic PCA data using tree diagrams.Research in bioanalysis and separations at the University of Nebraska - Lincoln.Using NMR metabolomics to investigate tricarboxylic acid cycle-dependent signal transduction in Staphylococcus epidermidisGlucose phosphorylation is required for Mycobacterium tuberculosis persistence in mice.The current state of drug discovery and a potential role for NMR metabolomics.NMR analysis of a stress response metabolic signaling networkPredicting the in vivo mechanism of action for drug leads using NMR metabolomicsRevisiting Protocols for the NMR Analysis of Bacterial MetabolomesApplied metabolomics in drug discovery.Thiadiazolidinones: a new class of alanine racemase inhibitors with antimicrobial activity against methicillin-resistant Staphylococcus aureus.Metabolomics Reveal d-Alanine:d-Alanine Ligase As the Target of d-Cycloserine in Mycobacterium tuberculosis.Metabolomics analysis identifies d-Alanine-d-Alanine ligase as the primary lethal target of d-Cycloserine in mycobacteriaDetermination of antiprotozoal drug mechanisms by metabolomics approaches.The use of functional genomics in conjunction with metabolomics for Mycobacterium tuberculosis research.Molecular basis underlying Mycobacterium tuberculosis D-cycloserine resistance. Is there a role for ubiquinone and menaquinone metabolic pathways?Safety and tolerability profile of second-line anti-tuberculosis medications.Neglected diseases prioritized in Brazil under the perspective of metabolomics: A review.Pharmacokinetic variations in cancer patients with liver dysfunction: applications and challenges of pharmacometabolomics.Comparative mass spectrometry-based metabolomics strategies for the investigation of microbial secondary metabolites.Exometabolome analysis identifies pyruvate dehydrogenase as a target for the antibiotic triphenylbismuthdichloride in multiresistant bacterial pathogens.Crystallization and preliminary X-ray study of a thermostable alanine racemase from Thermoanaerobacter tengcongensis MB4.Sample preparation of Mycobacterium tuberculosis extracts for nuclear magnetic resonance metabolomic studies.Characterization and preliminary mutation analysis of a thermostable alanine racemase from Thermoanaerobacter tengcongensis MB4.Unraveling the concentration-dependent metabolic response of Pseudomonas sp. HF-1 to nicotine stress by ¹H NMR-based metabolomics.The role of metabolomics in tuberculosis treatment research.
P2860
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P2860
Use of NMR metabolomics to analyze the targets of D-cycloserine in mycobacteria: role of D-alanine racemase.
description
2007 nî lūn-bûn
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2007年の論文
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2007年学术文章
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2007年学术文章
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2007年学术文章
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2007年学术文章
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2007年学术文章
@zh-my
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2007年學術文章
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name
Use of NMR metabolomics to ana ...... a: role of D-alanine racemase.
@en
Use of NMR metabolomics to ana ...... a: role of D-alanine racemase.
@nl
type
label
Use of NMR metabolomics to ana ...... a: role of D-alanine racemase.
@en
Use of NMR metabolomics to ana ...... a: role of D-alanine racemase.
@nl
prefLabel
Use of NMR metabolomics to ana ...... a: role of D-alanine racemase.
@en
Use of NMR metabolomics to ana ...... a: role of D-alanine racemase.
@nl
P2093
P2860
P356
P1476
Use of NMR metabolomics to ana ...... a: role of D-alanine racemase.
@en
P2093
Denise K Zinniel
Ofelia Chacon
Raul G Barletta
Robert J Fenton
Robert Powers
Steven Halouska
P2860
P304
P356
10.1021/PR0704332
P577
2007-11-03T00:00:00Z