Core sequence in the RNA motif recognized by the ErmE methyltransferase revealed by relaxing the fidelity of the enzyme for its target.
about
The tylosin resistance gene tlrB of Streptomyces fradiae encodes a methyltransferase that targets G748 in 23S rRNA.Minimal substrate features for Erm methyltransferases defined by using a combinatorial oligonucleotide library.Alanine-scanning mutagenesis of the predicted rRNA-binding domain of ErmC' redefines the substrate-binding site and suggests a model for protein-RNA interactions.Negative in vitro selection identifies the rRNA recognition motif for ErmE methyltransferase
P2860
Core sequence in the RNA motif recognized by the ErmE methyltransferase revealed by relaxing the fidelity of the enzyme for its target.
description
1999 nî lūn-bûn
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1999年の論文
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1999年学术文章
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1999年学术文章
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1999年学术文章
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1999年学术文章
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1999年学术文章
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1999年學術文章
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1999年學術文章
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name
Core sequence in the RNA motif ...... of the enzyme for its target.
@en
Core sequence in the RNA motif ...... of the enzyme for its target.
@nl
type
label
Core sequence in the RNA motif ...... of the enzyme for its target.
@en
Core sequence in the RNA motif ...... of the enzyme for its target.
@nl
prefLabel
Core sequence in the RNA motif ...... of the enzyme for its target.
@en
Core sequence in the RNA motif ...... of the enzyme for its target.
@nl
P2860
P1433
P1476
Core sequence in the RNA motif ...... y of the enzyme for its target
@en
P2093
L H Hansen
P2860
P304
P356
10.1017/S1355838299981451
P407
P577
1999-01-01T00:00:00Z