Identification of novel substrates for human cytochrome P450 2J2. - Wikidata - awgldk - TriplyDB

Identification of novel substrates for human cytochrome P450 2J2.

Identification of novel substrates for human cytochrome P450 2J2.

http://www.wikidata.org/entity/Q43239300

about

Peroxisome proliferator-activated receptors in regulation of cytochromes P450: new way to overcome multidrug resistance?An update on the role of intestinal cytochrome P450 enzymes in drug disposition Important role of CYP2J2 in protein kinase inhibitor degradation: a possible role in intratumor drug disposition and resistance Hepatic Cytochrome P450 Activity, Abundance, and Expression Throughout Human Development Time-dependent expression of cytochrome p450 epoxygenases during human prenatal development Immunochemical detection of cytochrome P450 enzymes in small intestine microsomes of male and female untreated juvenile cynomolgus monkeys Investigating the contribution of CYP2J2 to ritonavir metabolism in vitro and in vivo.Cytochrome P450 2J2: distribution, function, regulation, genetic polymorphisms and clinical significance.Very important pharmacogene summary: ABCB1 (MDR1, P-glycoprotein)Potential contribution of cytochrome P450 2B6 to hepatic 4-hydroxycyclophosphamide formation in vitro and in vivo Identifying a selective substrate and inhibitor pair for the evaluation of CYP2J2 activity Roles of the epoxygenase CYP2J2 in the endothelium.CYP2J2 and CYP2C19 are the major enzymes responsible for metabolism of albendazole and fenbendazole in human liver microsomes and recombinant P450 assay systems.Carbon-carbon bond cleavage in activation of the prodrug nabumetone.The effect and clinical consequences of hypoxia on cytochrome P450, membrane carrier proteins activity and expression.Extrahepatic metabolism at the body's internal-external interfaces.Editor's Highlight: Transgenic Zebrafish Reporter Lines as Alternative In Vivo Organ Toxicity Models.Expression and Characterization of Truncated Recombinant Human Cytochrome P450 2J2.PharmGKB summary: cytochrome P450, family 2, subfamily J, polypeptide 2: CYP2J2.Human cytochrome P450 oxidation of 5-hydroxythalidomide and pomalidomide, an amino analogue of thalidomide.Altered Protein Expression of Cardiac CYP2J and Hepatic CYP2C, CYP4A, and CYP4F in a Mouse Model of Type II Diabetes-A Link in the Onset and Development of Cardiovascular Disease?Angiotensin II Receptor Blockers Inhibit the Generation of Epoxyeicosatrienoic Acid from Arachidonic Acid in Recombinant CYP2C9, CYP2J2 and Human Liver Microsomes.Cytochrome P450 2J2, a new key enzyme in cyclophosphamide bioactivation and a potential biomarker for hematological malignancies.Terfenadine t-butyl hydroxylation catalyzed by human and marmoset cytochrome P450 3A and 4F enzymes in livers and small intestines.Computational modelling of the binding of arachidonic acid to the human monooxygenase CYP2J2.Marmoset cytochrome P450 2J2 mainly expressed in small intestines and livers effectively metabolizes human P450 2J2 probe substrates, astemizole and terfenadine.CYP2J2 expression in adult ventricular myocytes protects against external and drug induced ROS toxicity.Heme Modification Contributes to the Mechanism-Based Inactivation of Human Cytochrome P450 2J2 by Two Terminal Acetylenic Compounds.CYP2J2 - regulation, function and polymorphism.Non-linear increases in danazol exposure with dose in older vs. younger beagle dogs: the potential role of differences in bile salt concentration, thermodynamic activity, and formulation digestion Role of Arginine 117 in Substrate Recognition by Human Cytochrome P450 2J2

P2860

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P2860

Identification of novel substrates for human cytochrome P450 2J2.

http://www.wikidata.org/entity/Q43239300

description

2009 nî lūn-bûn

@nan

2009年の論文

@ja

2009年学术文章

@wuu

2009年学术文章

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2009年学术文章

@zh-cn

2009年学术文章

@zh-hans

2009年学术文章

@zh-my

2009年学术文章

@zh-sg

2009年學術文章

@yue

2009年學術文章

@zh-hant

name

Identification of novel substrates for human cytochrome P450 2J2.

@en

Identification of novel substrates for human cytochrome P450 2J2.

@nl

type

label

Identification of novel substrates for human cytochrome P450 2J2.

@en

Identification of novel substrates for human cytochrome P450 2J2.

@nl

prefLabel

Identification of novel substrates for human cytochrome P450 2J2.

@en

Identification of novel substrates for human cytochrome P450 2J2.

@nl

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P1433

Drug Metabolism and Disposition

P1476

Identification of novel substrates for human cytochrome P450 2J2.

@en

P2093

Andrea Clouser-Roche

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Caroline A Lee

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David Neul

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Deepak Dalvie

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J P Jones

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Michael R Wester

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Michael Zientek

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Rheem A Totah

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Sascha Freiwald

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Ying Jiang

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347-356

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scholarly article

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10.1124/DMD.109.030270

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2

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38

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2009-11-18T00:00:00Z

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38098993

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19923256

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