about
iCLIP: protein-RNA interactions at nucleotide resolutionRecursive splicing in long vertebrate genes.Identification of allele-specific RNAi effectors targeting genetic forms of Parkinson's diseaseProgressive Motor Neuron Pathology and the Role of Astrocytes in a Human Stem Cell Model of VCP-Related ALSThe biogenesis and characterization of mammalian microRNAs of mirtron origin.Artificial mirtron-mediated gene knockdown: functional DMPK silencing in mammalian cellsCLIPing the brain: studies of protein-RNA interactions important for neurodegenerative disorders.Lessons from non-canonical splicingThe miRNA pathway in neurological and skeletal muscle disease: implications for pathogenesis and therapy.Using human pluripotent stem cells to study post-transcriptional mechanisms of neurodegenerative diseases.Mirtrons, an emerging class of atypical miRNA.Regulation of gene expression through production of unstable mRNA isoforms.Insights into the design and interpretation of iCLIP experiments.The greatest catch: big game fishing for mRNA-bound proteins.The interaction of PRC2 with RNA or chromatin is mutually antagonistic.A neuroprotective astrocyte state is induced by neuronal signal EphB1 but fails in ALS models.Regulation of constitutive and alternative mRNA splicing across the human transcriptome by PRPF8 is determined by 5' splice site strength.Individual Nucleotide Resolution UV Cross-Linking and Immunoprecipitation (iCLIP) to Determine Protein-RNA Interactions.Transcript-specific characteristics determine the contribution of endo- and exonucleolytic decay pathways during the degradation of nonsense-mediated decay substrates.Identification of expression quantitative trait loci associated with schizophrenia and affective disorders in normal brain tissueP-TEFb activation by RBM7 shapes a pro-survival transcriptional response to genotoxic stressA systems view of spliceosomal assembly and branchpoints with iCLIP
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description
hulumtues
@sq
researcher
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wetenschapper
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հետազոտող
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name
Christopher R Sibley
@ast
Christopher R Sibley
@en
Christopher R Sibley
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Christopher R Sibley
@nl
Christopher R Sibley
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type
label
Christopher R Sibley
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Christopher R Sibley
@en
Christopher R Sibley
@es
Christopher R Sibley
@nl
Christopher R Sibley
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prefLabel
Christopher R Sibley
@ast
Christopher R Sibley
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Christopher R Sibley
@es
Christopher R Sibley
@nl
Christopher R Sibley
@sl
P108
P106
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P31
P496
0000-0002-8286-4683