Novel selective MMP-13 inhibitors reduce collagen degradation in bovine articular and human osteoarthritis cartilage explants.
about
Lumican: a new inhibitor of matrix metalloproteinase-14 activitySimple Pseudo-dipeptides with a P2' Glutamate: A NOVEL INHIBITOR FAMILY OF MATRIX METALLOPROTEASES AND OTHER METZINCINSCheminformatics-based drug design approach for identification of inhibitors targeting the characteristic residues of MMP-13 hemopexin domainPotential of Pseudoshikonin I Isolated from Lithospermi Radix as Inhibitors of MMPs in IL-1β-Induced SW1353 CellsSAR Studies of Exosite-Binding Substrate-Selective Inhibitors of A Disintegrin And Metalloprotease 17 (ADAM17) and Application as Selective in Vitro Probes.Metalloproteinase binding proteins: WO2009097397.Characterization of selective exosite-binding inhibitors of matrix metalloproteinase 13 that prevent articular cartilage degradation in vitro.Profiling the secretion of soluble mediators by end stage osteoarthritis synovial tissue explants reveals a reduced responsiveness to an inflammatory trigger.Selective inhibition of matrix metalloproteinase-13 increases collagen content of established mouse atherosclerosis.New strategies for targeting matrix metalloproteinasesProteases involved in cartilage matrix degradation in osteoarthritis.The history of matrix metalloproteinases: milestones, myths, and misperceptions.In vivo evaluation of Mg-6Zn and titanium alloys on collagen metabolism in the healing of intestinal anastomosis.CIINE Reflects Collagenase-Specific CII Breakdown in Cartilage Explant and Whole Body of CanineEffect of dentin etching and chlorhexidine application on metalloproteinase-mediated collagen degradationZinc reduces collagen degradation in demineralized human dentin explantsSmall molecule inhibitors of WNT/β-catenin signaling block IL-1β- and TNFα-induced cartilage degradation.Scarless wound healing.Clinical implications of compounds designed to inhibit ECM-modifying metalloproteinases.Identification of novel, exosite-binding matrix metalloproteinase-13 inhibitor scaffolds.Recent Research Advances in Selective Matrix Metalloproteinase-13 Inhibitors as Anti-Osteoarthritis Agents.Coptisine Prevented IL-β-Induced Expression of Inflammatory Mediators in Chondrocytes.MicroRNA-411 inhibited matrix metalloproteinase 13 expression in human chondrocytes.Prospects for treating osteoarthritis: enzyme-protein interactions regulating matrix metalloproteinase activity.Effects of adenovirus-mediated bFGF, IL-1Ra and IGF-1 gene transfer on human osteoarthritic chondrocytes and osteoarthritis in rabbits.Current status and future prospects for disease modification in osteoarthritis.Functional characterization of selective exosite-binding inhibitors of matrix metalloproteinase-13 (MMP-13) - experimental validation in human breast and colon cancer.
P2860
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P2860
Novel selective MMP-13 inhibitors reduce collagen degradation in bovine articular and human osteoarthritis cartilage explants.
description
2009 nî lūn-bûn
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2009年の論文
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2009年学术文章
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2009年学术文章
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2009年学术文章
@zh-cn
2009年学术文章
@zh-hans
2009年学术文章
@zh-my
2009年学术文章
@zh-sg
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2009年學術文章
@zh-hant
name
Novel selective MMP-13 inhibit ...... oarthritis cartilage explants.
@en
Novel selective MMP-13 inhibit ...... oarthritis cartilage explants.
@nl
type
label
Novel selective MMP-13 inhibit ...... oarthritis cartilage explants.
@en
Novel selective MMP-13 inhibit ...... oarthritis cartilage explants.
@nl
prefLabel
Novel selective MMP-13 inhibit ...... oarthritis cartilage explants.
@en
Novel selective MMP-13 inhibit ...... oarthritis cartilage explants.
@nl
P2093
P1476
Novel selective MMP-13 inhibit ...... oarthritis cartilage explants.
@en
P2093
Andreas Jaworski
Andreas Timmermann
Dorothea Piecha
Gabriele Becher
Heike Kheil
Jürgen Weik
Maren Burger
Michael W Hofmann
P2888
P304
P356
10.1007/S00011-009-0112-9
P577
2009-11-10T00:00:00Z