A progressive dopaminergic phenotype associated with neurotoxic conversion of α-synuclein in BAC-transgenic rats.
about
Adult hippocampal neurogenesis in Parkinson's disease: impact on neuronal survival and plasticityRodent models in neuroscience research: is it a rat race?Severely impaired hippocampal neurogenesis associates with an early serotonergic deficit in a BAC α-synuclein transgenic rat model of Parkinson's disease.Reducing C-terminal-truncated alpha-synuclein by immunotherapy attenuates neurodegeneration and propagation in Parkinson's disease-like models.Overexpression of the calpain-specific inhibitor calpastatin reduces human alpha-Synuclein processing, aggregation and synaptic impairment in [A30P]αSyn transgenic mice.Modeling Alzheimer's disease in transgenic ratsEnvironmental neurotoxic challenge of conditional alpha-synuclein transgenic mice predicts a dopaminergic olfactory-striatal interplay in early PD.The association of SNCA with hazardous alcohol use is mediated by impulsivity.Olfactory assays for mouse models of neurodegenerative disease.Up-regulation of SNCA gene expression: implications to synucleinopathiesParadoxical antidepressant effects of alcohol are related to acid sphingomyelinase and its control of sphingolipid homeostasis.α-Synuclein in the olfactory system in Parkinson's disease: role of neural connections on spreading pathology.Mechanisms of alpha-synuclein action on neurotransmission: cell-autonomous and non-cell autonomous roleAlpha-synuclein propagation: New insights from animal models.Development of Passive Immunotherapies for Synucleinopathies.Sequential Extraction of Soluble and Insoluble Alpha-Synuclein from Parkinsonian Brains.Accumulation of oligomer-prone α-synuclein exacerbates synaptic and neuronal degeneration in vivoEarly Degeneration of Both Dopaminergic and Serotonergic Axons - A Common Mechanism in Parkinson's Disease.Hippocampal neuronal cells that accumulate α-synuclein fragments are more vulnerable to Aβ oligomer toxicity via mGluR5--implications for dementia with Lewy bodies.Genomic predictors of remission to antidepressant treatment in geriatric depression using genome-wide expression analyses: a pilot study.An early axonopathy in a hLRRK2(R1441G) transgenic model of Parkinson disease.Alpha-synuclein prevents the formation of spherical mitochondria and apoptosis under oxidative stressOverexpression of synphilin-1 promotes clearance of soluble and misfolded alpha-synuclein without restoring the motor phenotype in aged A30P transgenic mice.Autophagy inhibition promotes SNCA/alpha-synuclein release and transfer via extracellular vesicles with a hybrid autophagosome-exosome-like phenotype.A novel vector for transgenesis in the rat CNS.Dopaminergic lesioning impairs adult hippocampal neurogenesis by distinct modification of α-synuclein.Oral administration of Proteus mirabilis damages dopaminergic neurons and motor functions in mice.Prenatal androgen receptor activation determines adult alcohol and water drinking in a sex-specific way.New developments in genetic rat models of Parkinson's disease.[Cellular replacement strategies and adult neurogenesis in idiopathic Parkinson's disease].Environmental Enrichment Prevents Transcriptional Disturbances Induced by Alpha-Synuclein Overexpression.Quality Over Quantity: Advantages of Using Alpha-Synuclein Preformed Fibril Triggered Synucleinopathy to Model Idiopathic Parkinson's Disease
P2860
Q26862840-2144FF0A-84A0-4250-BA78-40B31248163EQ28071614-27328DA8-FB05-44FA-8667-90EE236E8004Q30795299-5F23F63F-ACDF-49D8-8F31-645A8385E2EBQ33865366-E624AAC8-F8AD-4346-88AD-BFFDCF171C26Q33947949-2DEEC0BC-41FF-46B9-9DDB-0689DF10B16DQ34508624-DE3EFE74-E644-467A-80E1-F030578DEB5EQ35073958-9CB26099-B973-45CF-B3B7-21EFE271FE8EQ35668655-E497342D-BDD8-4311-A413-6770DAAD10AFQ36787949-5FAF6AE2-668C-48F3-96B5-6F7E16B6D9F3Q37004246-8718A806-2C90-4992-B356-A6D76797FD4CQ37666339-211488DE-22C8-49D4-AC82-1FA6DDA5E1A0Q38153587-1EA0043E-5574-47F3-A9B7-879E7679240AQ38488082-EAB28515-BEAD-496C-BBC1-D698C238CC0FQ38582573-C2A7998A-63A5-408D-B0DD-63E231F96EB3Q38679627-F1A149CA-E59F-4EF1-8BD3-F7287BB5424AQ38819135-D2E1AF18-F6C1-46E1-9EA5-E7364C07835EQ38966914-61DB0D6F-53FE-470B-A352-CC39A750E784Q39075710-02B5160D-0695-4E17-9357-2C86EB8C04E2Q40150743-A91928F0-6CF2-4980-9DB2-8C97C68DD148Q41494507-83F09077-D0B7-4CF0-A067-ADC34EEE3AF1Q41916939-19AF313C-1714-41FA-BDE3-43AE91AA7BF1Q42320467-2BC6CB33-DBC3-4793-BF04-A81E73FE7298Q43752239-11827A51-BC0E-42A4-BFF7-239F4529654DQ45990397-E5450034-FA50-4515-AE35-23EB49D90B29Q46283809-7C650462-3CAF-4681-A0E5-3CD964C7649CQ46657177-52654F1F-9387-403E-86C0-AEF110FAA09FQ47851066-6068F884-C8CE-4060-99D6-F6687B926C0FQ47942495-1D6CA900-06AE-48F6-B63F-0721B486840BQ48502440-63935561-7748-4B86-BCCE-A72D7C33E53CQ50242092-F11F5D14-6006-4329-B935-C7B90435C833Q54942969-7E8CE6ED-D6C5-4713-9C48-5401826E5712Q58764665-996A8EFF-9C2F-48C8-939F-EDB5F7E82665
P2860
A progressive dopaminergic phenotype associated with neurotoxic conversion of α-synuclein in BAC-transgenic rats.
description
2013 nî lūn-bûn
@nan
2013年の論文
@ja
2013年学术文章
@wuu
2013年学术文章
@zh
2013年学术文章
@zh-cn
2013年学术文章
@zh-hans
2013年学术文章
@zh-my
2013年学术文章
@zh-sg
2013年學術文章
@yue
2013年學術文章
@zh-hant
name
A progressive dopaminergic phe ...... uclein in BAC-transgenic rats.
@en
A progressive dopaminergic phe ...... uclein in BAC-transgenic rats.
@nl
type
label
A progressive dopaminergic phe ...... uclein in BAC-transgenic rats.
@en
A progressive dopaminergic phe ...... uclein in BAC-transgenic rats.
@nl
prefLabel
A progressive dopaminergic phe ...... uclein in BAC-transgenic rats.
@en
A progressive dopaminergic phe ...... uclein in BAC-transgenic rats.
@nl
P2093
P2860
P50
P921
P356
P1433
P1476
A progressive dopaminergic phe ...... uclein in BAC-transgenic rats.
@en
P2093
Anthony Adame
Bernd J Pichler
Christiane Giel
Claudia Bauer
Davide Amato
Florian Harmuth
Frank Zimmermann
Hodaka Yamakado
Juergen Winkler
Kai Schönig
P2860
P304
P356
10.1093/BRAIN/AWS358
P407
P50
P577
2013-02-01T00:00:00Z