Consequences of long-term oral administration of the mitochondria-targeted antioxidant MitoQ to wild-type mice.
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Targeting mitochondrial reactive oxygen species as novel therapy for inflammatory diseases and cancersCardiac dysfunction and oxidative stress in the metabolic syndrome: an update on antioxidant therapiesMitochondria as a therapeutic target in heart failureMitochondrial biogenesis: regulation by endogenous gases during inflammation and organ stressUnderstanding and preventing mitochondrial oxidative damageInactivation of pyruvate dehydrogenase kinase 2 by mitochondrial reactive oxygen speciesA mitochondrial-targeted coenzyme q analog prevents weight gain and ameliorates hepatic dysfunction in high-fat-fed miceNutritional countermeasures targeting reactive oxygen species in cancer: from mechanisms to biomarkers and clinical evidenceMitochondrial ROS regulate thermogenic energy expenditure and sulfenylation of UCP1The swan-neck lesion: proximal tubular adaptation to oxidative stress in nephropathic cystinosis.Mitochondria-targeted dodecyltriphenylphosphonium (C12TPP) combats high-fat-diet-induced obesity in miceMitochondria in Alzheimer's Disease and Diabetes-Associated Neurodegeneration: License to Heal!Mitochondrial oxidative stress and mammalian healthspan.Targeting mitochondria-derived reactive oxygen species to reduce epithelial barrier dysfunction and colitis.Mitochondrial targeting of vitamin E succinate enhances its pro-apoptotic and anti-cancer activity via mitochondrial complex IINeuroprotective strategies involving ROS in Alzheimer disease.Molecular strategies for targeting antioxidants to mitochondria: therapeutic implications.The role of mitochondrial DNA mutation on neurodegenerative diseases.Mitochondrial anti-oxidant protects IEX-1 deficient mice from organ damage during endotoxemia.mtDNA Mutagenesis Disrupts Pluripotent Stem Cell Function by Altering Redox Signaling.The mitochondria-targeted antioxidant MitoQ prevents loss of spatial memory retention and early neuropathology in a transgenic mouse model of Alzheimer's disease.Loss of PLA2G6 leads to elevated mitochondrial lipid peroxidation and mitochondrial dysfunction.Nanotechnology inspired tools for mitochondrial dysfunction related diseases.The mitochondria-targeted antioxidant MitoQ attenuates liver fibrosis in mice.Selective Mitochondrial Targeting Exerts Anxiolytic Effects In Vivo.MitoQ, a mitochondria-targeted antioxidant, delays disease progression and alleviates pathogenesis in an experimental autoimmune encephalomyelitis mouse model of multiple sclerosis.Long-term administration of the mitochondria-targeted antioxidant mitoquinone mesylate fails to attenuate age-related oxidative damage or rescue the loss of muscle mass and function associated with aging of skeletal muscle.P-glycoprotein (Mdr1a/1b) and breast cancer resistance protein (Bcrp) decrease the uptake of hydrophobic alkyl triphenylphosphonium cations by the brain.Mitochondria-targeted antioxidants for treatment of Parkinson's disease: preclinical and clinical outcomes.Mitochondrial medicine for neurodegenerative diseases.A midlife crisis for the mitochondrial free radical theory of aging.Metabolic effects of a mitochondrial-targeted coenzyme Q analog in high fat fed obese mice.Endothelial mitochondria and heart disease.Metabolic manipulators: a well founded strategy to combat mitochondrial dysfunction.Neurodevelopmental manifestations of mitochondrial disease.Polyphenols and human health: a prospectus.Perspectives and potential applications of mitochondria-targeted antioxidants in cardiometabolic diseases and type 2 diabetes.The centrality of mitochondria in the pathogenesis and treatment of Parkinson's disease.Mitochondrial potassium channels as pharmacological target for cardioprotective drugs.Intracellular redox state as target for anti-influenza therapy: are antioxidants always effective?
P2860
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P2860
Consequences of long-term oral administration of the mitochondria-targeted antioxidant MitoQ to wild-type mice.
description
2009 nî lūn-bûn
@nan
2009年の論文
@ja
2009年学术文章
@wuu
2009年学术文章
@zh
2009年学术文章
@zh-cn
2009年学术文章
@zh-hans
2009年学术文章
@zh-my
2009年学术文章
@zh-sg
2009年學術文章
@yue
2009年學術文章
@zh-hant
name
Consequences of long-term oral ...... idant MitoQ to wild-type mice.
@en
Consequences of long-term oral ...... idant MitoQ to wild-type mice.
@nl
type
label
Consequences of long-term oral ...... idant MitoQ to wild-type mice.
@en
Consequences of long-term oral ...... idant MitoQ to wild-type mice.
@nl
prefLabel
Consequences of long-term oral ...... idant MitoQ to wild-type mice.
@en
Consequences of long-term oral ...... idant MitoQ to wild-type mice.
@nl
P2093
P50
P1476
Consequences of long-term oral ...... xidant MitoQ to wild-type mice
@en
P2093
Andrew M James
Angela Logan
Anthony C Smith
Bruce A Jones
Claudia Rose
David C Rubinsztein
Helena M Cochemé
Ian M Fearnley
Ian McFarlane
Irina Abakumova
P304
P356
10.1016/J.FREERADBIOMED.2009.10.039
P577
2009-10-23T00:00:00Z