about
Cellular and molecular mechanisms of metformin: an overviewThe SWI/SNF chromatin-remodeling complex subunit SNF5 is essential for hepatocyte differentiationHigh levels of dietary stearate promote adiposity and deteriorate hepatic insulin sensitivity.Hepatocyte-specific IKKβ expression aggravates atherosclerosis development in APOE*3-Leiden miceThe dopamine receptor D2 agonist bromocriptine inhibits glucose-stimulated insulin secretion by direct activation of the alpha2-adrenergic receptors in beta cells.Hepatocyte-specific IKK-β activation enhances VLDL-triglyceride production in APOE*3-Leiden miceCirculating insulin stimulates fatty acid retention in white adipose tissue via KATP channel activation in the central nervous system only in insulin-sensitive mice.Helminth infections and type 2 diabetes: a cluster-randomized placebo controlled SUGARSPIN trial in Nangapanda, Flores, Indonesia.Metformin activates AMP-activated protein kinase in primary human hepatocytes by decreasing cellular energy statusStimulatory effect of insulin on glucose uptake by muscle involves the central nervous system in insulin-sensitive miceInfection with Soil-Transmitted Helminths Is Associated with Increased Insulin Sensitivity.A gene variant near ATM is significantly associated with metformin treatment response in type 2 diabetes: a replication and meta-analysis of five cohorts.A worm of one's own: how helminths modulate host adipose tissue function and metabolismTargeting AMPK: From Ancient Drugs to New Small-Molecule Activators.Activation of AMP-activated protein kinase in the liver: a new strategy for the management of metabolic hepatic disorders.Prednisolone induces the Wnt signalling pathway in 3T3-L1 adipocytes.The CTRB1/2 locus affects diabetes susceptibility and treatment via the incretin pathway.AMPK: Lessons from transgenic and knockout animalsThe insulin sensitizing effect of topiramate involves KATP channel activation in the central nervous systemBeyond AICA riboside: in search of new specific AMP-activated protein kinase activators.AMP-activated protein kinase in the regulation of hepatic energy metabolism: from physiology to therapeutic perspectives.Priming dendritic cells for th2 polarization: lessons learned from helminths and implications for metabolic disorders.Metformin: from mechanisms of action to therapies.Prevention of steatohepatitis by pioglitazone: implication of adiponectin-dependent inhibition of SREBP-1c and inflammation.Lipid droplet dynamics and insulin sensitivity upon a 5-day high-fat diet in Caucasians and South AsiansImpact of Metformin and compound C on NIS expression and iodine uptake in vitro and in vivo: a role for CRE in AMPK modulation of thyroid function.Metformin lowers plasma triglycerides by promoting VLDL-triglyceride clearance by brown adipose tissue in mice.Prednisolone-induced beta cell dysfunction is associated with impaired endoplasmic reticulum homeostasis in INS-1E cells.Phosphorylation of PRAS40 on Thr246 by PKB/AKT facilitates efficient phosphorylation of Ser183 by mTORC1.Hypoxia-inducible factor prolyl hydroxylase 1 (PHD1) deficiency promotes hepatic steatosis and liver-specific insulin resistance in mice.Metformin prevents high-glucose-induced endothelial cell death through a mitochondrial permeability transition-dependent process.Metformin inhibits mitochondrial permeability transition and cell death: a pharmacological in vitro study.Chronic helminth infection and helminth-derived egg antigens promote adipose tissue M2 macrophages and improve insulin sensitivity in obese mice.AMP-activated protein kinase-independent inhibition of hepatic mitochondrial oxidative phosphorylation by AICA riboside.Short-term high-fat diet increases macrophage markers in skeletal muscle accompanied by impaired insulin signalling in healthy male subjects.Peripheral cannabinoid 1 receptor blockade activates brown adipose tissue and diminishes dyslipidemia and obesity.Proline-rich Akt substrate of 40-kDa contains a nuclear export signal.Development of hepatic fibrosis occurs normally in AMPK-deficient mice.Glucose 6-phosphate hydrolysis is activated by glucagon in a low temperature-sensitive manner.Effects of prolonged fasting on AMPK signaling, gene expression, and mitochondrial respiratory chain content in skeletal muscle from lean and obese individuals.
P50
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P50
description
hulumtues
@sq
onderzoeker
@nl
researcher
@en
հետազոտող
@hy
name
Bruno Guigas
@ast
Bruno Guigas
@en
Bruno Guigas
@es
Bruno Guigas
@nl
Bruno Guigas
@sl
type
label
Bruno Guigas
@ast
Bruno Guigas
@en
Bruno Guigas
@es
Bruno Guigas
@nl
Bruno Guigas
@sl
prefLabel
Bruno Guigas
@ast
Bruno Guigas
@en
Bruno Guigas
@es
Bruno Guigas
@nl
Bruno Guigas
@sl
P108
P1053
M-2515-2015
P106
P1153
7801346250
P21
P2798
P31
P3829
P496
0000-0002-8856-5799