Identification of a potent and highly efficacious, yet slowly desensitizing CB1 cannabinoid receptor agonist.
about
Care and feeding of the endocannabinoid system: a systematic review of potential clinical interventions that upregulate the endocannabinoid system.Endocannabinoids selectively enhance sweet tasteCannabinoid-based drugs targeting CB1 and TRPV1, the sympathetic nervous system, and arthritisChemical probes of endocannabinoid metabolismPharmacotherapeutic modulation of the endocannabinoid signalling system in psychiatric disorders: drug-discovery strategiesLigand-specific endocytic dwell times control functional selectivity of the cannabinoid receptor 1Chronic monoacylglycerol lipase blockade causes functional antagonism of the endocannabinoid system.Reduction in endocannabinoid tone is a homeostatic mechanism for specific inhibitory synapses.Prolonged monoacylglycerol lipase blockade causes equivalent cannabinoid receptor type 1 receptor-mediated adaptations in fatty acid amide hydrolase wild-type and knockout miceAgonist-selective mechanisms of GPCR desensitizationCannabinoid receptors: where they are and what they do.Endocannabinoid modulation by FAAH and monoacylglycerol lipase within the analgesic circuitry of the periaqueductal greyEndocannabinoid modulation of cortical up-states and NREM sleep.Cannabinoids, electrophysiology, and retrograde messengers: challenges for the next 5 yearsMechanisms of CB1 receptor signaling: endocannabinoid modulation of synaptic strength.Binding between a distal C-terminus fragment of cannabinoid receptor 1 and arrestin-2.Novel adamantyl cannabinoids as CB1 receptor probes.Synthesis and characterization of 2-substituted bornane pharmacophores for novel cannabinergic ligandsDifferential alteration of hippocampal excitatory synaptic transmission by cannabinoid ligands.Latest advances in cannabinoid receptor agonists.Cannabinoid conditioned reward and aversion: behavioral and neural processes.Ligand functional selectivity and quantitative pharmacology at G protein-coupled receptors.An Introduction to the Endogenous Cannabinoid System.∆(9)-Tetrahydrocannabinol decreases NOP receptor density and mRNA levels in human SH-SY5Y cells.A high efficacy cannabinergic ligand (AM4054) used as a discriminative stimulus: Generalization to other adamantyl analogs and Δ(9)-THC in ratsCannabinoids Activate Monoaminergic Signaling to Modulate Key C. elegans Behaviors.Presynaptic inhibition of gamma-aminobutyric acid release in the bed nucleus of the stria terminalis by kappa opioid receptor signaling.Depolarization-induced suppression of excitation in murine autaptic hippocampal neurones.Effects of centrally administered endocannabinoids and opioids on orofacial pain perception in rats.
P2860
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P2860
Identification of a potent and highly efficacious, yet slowly desensitizing CB1 cannabinoid receptor agonist.
description
2004 nî lūn-bûn
@nan
2004年の論文
@ja
2004年学术文章
@wuu
2004年学术文章
@zh
2004年学术文章
@zh-cn
2004年学术文章
@zh-hans
2004年学术文章
@zh-my
2004年学术文章
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2004年學術文章
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2004年學術文章
@zh-hant
name
Identification of a potent and ...... cannabinoid receptor agonist.
@en
Identification of a potent and ...... cannabinoid receptor agonist.
@nl
type
label
Identification of a potent and ...... cannabinoid receptor agonist.
@en
Identification of a potent and ...... cannabinoid receptor agonist.
@nl
prefLabel
Identification of a potent and ...... cannabinoid receptor agonist.
@en
Identification of a potent and ...... cannabinoid receptor agonist.
@nl
P2093
P2860
P921
P356
P1476
Identification of a potent and ...... cannabinoid receptor agonist.
@en
P2093
Alexander Zvonok
Charles Chavkin
Wenzhen Jin
Xin-Zhong Lin
P2860
P304
P356
10.1038/SJ.BJP.0705792
P407
P577
2004-05-17T00:00:00Z