A new era in iron chelation therapy: the design of optimal, individually adjusted iron chelation therapies for the complete removal of iron overload in thalassemia and other chronically transfused patients.
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Efficacy and safety of iron-chelation therapy with deferoxamine, deferiprone, and deferasirox for the treatment of iron-loaded patients with non-transfusion-dependent thalassemia syndromesWorld health dilemmas: Orphan and rare diseases, orphan drugs and orphan patientsPhytochelators Intended for Clinical Use in Iron Overload, Other Diseases of Iron Imbalance and Free Radical PathologyMore pieces to the iron chelation puzzle.How I treat Diamond-Blackfan anemia.Transition of Thalassaemia and Friedreich ataxia from fatal to chronic diseases.Improved R2* liver iron concentration assessment using a novel fuzzy c-mean clustering scheme.New developments and controversies in iron metabolism and iron chelation therapy.Introduction of higher doses of deferasirox: better efficacy but not effective iron removal from the heart and increased risks of serious toxicities.Potential clinical applications of chelating drugs in diseases targeting transferrin-bound iron and other metals.Expression of an innate immune element (mouse hepcidin-1) in baculovirus expression system and the comparison of its function with synthetic human hepcidin-25.Iron chelation therapy in hereditary hemochromatosis and thalassemia intermedia: regulatory and non regulatory mechanisms of increased iron absorption.Maintenance of normal range body iron store levels for up to 4.5 years in thalassemia major patients using deferiprone monotherapy.A record of 1320 suspect, deferasirox-related, patient deaths reported in 2009: insufficient toxicity testing, low efficacy and lack of transparency may endanger the lives of iron loaded patients.The proceedings of the 20th International Conference on Chelation held in the USA: advances on new and old chelation therapies.Efficacy, compliance and toxicity factors are affecting the rate of normalization of body iron stores in thalassemia patients using the deferiprone and deferoxamine combination therapy.The proceedings of the 19Th international conference on chelation held in London, United Kingdom: major changes in iron chelation therapy in the last 25 years using deferiprone (L1) has resulted in the complete treatment of iron overload.The 18th ICOC Proceedings in Athens, Greece: New breakthrough in thalassemia leading to the complete treatment of iron overload and to hundreds of patients achieving and maintaining normal body iron stores. Ethical questions on chelation therapy.
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P2860
A new era in iron chelation therapy: the design of optimal, individually adjusted iron chelation therapies for the complete removal of iron overload in thalassemia and other chronically transfused patients.
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2009 nî lūn-bûn
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name
A new era in iron chelation th ...... ronically transfused patients.
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A new era in iron chelation th ...... ronically transfused patients.
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A new era in iron chelation th ...... ronically transfused patients.
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A new era in iron chelation th ...... ronically transfused patients.
@nl
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A new era in iron chelation th ...... ronically transfused patients.
@en
A new era in iron chelation th ...... ronically transfused patients.
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P2860
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A new era in iron chelation th ...... ronically transfused patients.
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George J Kontoghiorghes
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10.3109/03630260903217182
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2009-01-01T00:00:00Z