Regulation of leucine uptake by tor1+ in Schizosaccharomyces pombe is sensitive to rapamycin.
about
Transcriptional activation of the general amino acid permease gene per1 by the histone deacetylase Clr6 Is regulated by Oca2 kinaseFission yeast TORC1 regulates phosphorylation of ribosomal S6 proteins in response to nutrients and its activity is inhibited by rapamycin.Growth and the Environment of Schizosaccharomyces pombeIdentification and functional analysis of the erh1(+) gene encoding enhancer of rudimentary homolog from the fission yeast Schizosaccharomyces pombeChemical genomics approach to identify genes associated with sensitivity to rapamycin in the fission yeast Schizosaccharomyces pombe.Point mutations in TOR confer Rheb-independent growth in fission yeast and nutrient-independent mammalian TOR signaling in mammalian cellsAltered nuclear tRNA metabolism in La-deleted Schizosaccharomyces pombe is accompanied by a nutritional stress response involving Atf1p and Pcr1p that is suppressible by Xpo-t/Los1pTOR complex 2 (TORC2) in Dictyostelium suppresses phagocytic nutrient capture independently of TORC1-mediated nutrient sensing.Rhb1 regulates the expression of secreted aspartic protease 2 through the TOR signaling pathway in Candida albicans.Efficient Tor signaling requires a functional class C Vps protein complex in Saccharomyces cerevisiaeLeu1 plays a role in iron metabolism and is required for virulence in Cryptococcus neoformans.The amino acid sensitive TOR pathway from yeast to mammals.Psk1, an AGC kinase family member in fission yeast, is directly phosphorylated and controlled by TORC1 and functions as S6 kinaseLack of tRNA modification isopentenyl-A37 alters mRNA decoding and causes metabolic deficiencies in fission yeast.TORC1 signaling is governed by two negative regulators in fission yeast.Signaling cascades as drug targets in model and pathogenic fungi.An aging-independent replicative lifespan in a symmetrically dividing eukaryote.TOR links starvation responses to telomere length maintenance.Functional diversity and pharmacological profiles of the FKBPs and their complexes with small natural ligands.Crosstalk between the Tor and Gcn2 pathways in response to different stressesLoss of the TOR kinase Tor2 mimics nitrogen starvation and activates the sexual development pathway in fission yeast.Isp7 is a novel regulator of amino acid uptake in the TOR signaling pathway.fhl1 gene of the fission yeast regulates transcription of meiotic genes and nitrogen starvation response, downstream of the TORC1 pathway.The Vam6 and Gtr1-Gtr2 pathway activates TORC1 in response to amino acids in fission yeastGad8 Protein Is Found in the Nucleus Where It Interacts with the MluI Cell Cycle Box-binding Factor (MBF) Transcriptional Complex to Regulate the Response to DNA Replication Stress.TORC1 Regulates Developmental Responses to Nitrogen Stress via Regulation of the GATA Transcription Factor Gaf1.The SAGA histone acetyltransferase complex regulates leucine uptake through the Agp3 permease in fission yeast.Opposite effects of tor1 and tor2 on nitrogen starvation responses in fission yeastThe Tsc/Rheb signaling pathway controls basic amino acid uptake via the Cat1 permease in fission yeast.The reverse, but coordinated, roles of Tor2 (TORC1) and Tor1 (TORC2) kinases for growth, cell cycle and separase-mediated mitosis in Schizosaccharomyces pombe.TOR complex 2 controls gene silencing, telomere length maintenance, and survival under DNA-damaging conditions.TORC2 is required to maintain genome stability during S phase in fission yeast.Glucose restriction induces transient G2 cell cycle arrest extending cellular chronological lifespan.Rapid regulation of nuclear proteins by rapamycin-induced translocation in fission yeast.Glucose activates TORC2-Gad8 protein via positive regulation of the cAMP/cAMP-dependent protein kinase A (PKA) pathway and negative regulation of the Pmk1 protein-mitogen-activated protein kinase pathway.Conservation of the Tsc/Rheb/TORC1/S6K/S6 Signaling in Fission Yeast.Fission yeast TOR signaling is essential for the down-regulation of a hyperactivated stress-response MAP kinase under salt stress.Identification of novel single amino acid changes that result in hyperactivation of the unique GTPase, Rheb, in fission yeast.Using genetic buffering relationships identified in fission yeast to reveal susceptibilities in cells lacking hamartin or tuberin function.Screening for long-lived genes identifies Oga1, a guanine-quadruplex associated protein that affects the chronological lifespan of the fission yeast Schizosaccharomyces pombe.
P2860
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P2860
Regulation of leucine uptake by tor1+ in Schizosaccharomyces pombe is sensitive to rapamycin.
description
2004 nî lūn-bûn
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2004年の論文
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2004年学术文章
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2004年学术文章
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name
Regulation of leucine uptake b ...... mbe is sensitive to rapamycin.
@en
Regulation of leucine uptake b ...... mbe is sensitive to rapamycin.
@nl
type
label
Regulation of leucine uptake b ...... mbe is sensitive to rapamycin.
@en
Regulation of leucine uptake b ...... mbe is sensitive to rapamycin.
@nl
prefLabel
Regulation of leucine uptake b ...... mbe is sensitive to rapamycin.
@en
Regulation of leucine uptake b ...... mbe is sensitive to rapamycin.
@nl
P2093
P2860
P1433
P1476
Regulation of leucine uptake b ...... mbe is sensitive to rapamycin.
@en
P2093
Irina Roitburg
Martin Kupiec
Ronit Weisman
Tal Nahari
P2860
P304
P356
10.1534/GENETICS.104.034983
P407
P577
2004-09-30T00:00:00Z