Reduced calcineurin protein levels and activity in exon-1 mouse models of Huntington's disease: role in excitotoxicity.

Reduced calcineurin protein levels and activity in exon-1 mouse models of Huntington's disease: role in excitotoxicity.

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http://www.wikidata.org/entity/Q43280390
Possible involvement of self-defense mechanisms in the preferential vulnerability of the striatum in Huntington's diseaseStriatal-enriched protein tyrosine phosphatase expression and activity in Huntington's disease: a STEP in the resistance to excitotoxicityTherapeutic implications for striatal-enriched protein tyrosine phosphatase (STEP) in neuropsychiatric disorders.The Role of Striatal-Enriched Protein Tyrosine Phosphatase (STEP) in Cognition.Pathophysiology of Huntington's disease: time-dependent alterations in synaptic and receptor function.Huntington's disease and the striatal medium spiny neuron: cell-autonomous and non-cell-autonomous mechanisms of diseaseIs Huntington's disease a tauopathy?Faulty splicing and cytoskeleton abnormalities in Huntington's disease.Cognitive dysfunction in Huntington's disease: mechanisms and therapeutic strategies beyond BDNF.Tau hyperphosphorylation and deregulation of calcineurin in mouse models of Huntington's disease.Early down-regulation of PKCδ as a pro-survival mechanism in Huntington's disease.Decreased glycogen synthase kinase-3 levels and activity contribute to Huntington's disease.Prostaglandin E2 EP1 receptor antagonist improves motor deficits and rescues memory decline in R6/1 mouse model of Huntington's disease.Mutant huntingtin alters Tau phosphorylation and subcellular distribution.Increased PKA signaling disrupts recognition memory and spatial memory: role in Huntington's disease.Activation of Elk-1 participates as a neuroprotective compensatory mechanism in models of Huntington's disease.7,8-dihydroxyflavone ameliorates cognitive and motor deficits in a Huntington's disease mouse model through specific activation of the PLCγ1 pathway.
P2860

Reduced calcineurin protein levels and activity in exon-1 mouse models of Huntington's disease: role in excitotoxicity.

Item
http://www.wikidata.org/entity/Q43280390
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2009 nî lūn-bûn
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Reduced calcineurin protein le ...... sease: role in excitotoxicity.
@en
Reduced calcineurin protein le ...... sease: role in excitotoxicity.
@nl
type
label
Reduced calcineurin protein le ...... sease: role in excitotoxicity.
@en
Reduced calcineurin protein le ...... sease: role in excitotoxicity.
@nl
prefLabel
Reduced calcineurin protein le ...... sease: role in excitotoxicity.
@en
Reduced calcineurin protein le ...... sease: role in excitotoxicity.
@nl
P1433
P1476
P2093
P304
P31
P356
P433
P478
P50
P577
P5875
P698
P921
P356
P1433
P1476
Reduced calcineurin protein le ...... isease: role in excitotoxicity
@en
P2093
P304
P31
P356
P433
P478
P50
P577
P5875
P698
P921