about
Cyclooxygenase-2 controls energy homeostasis in mice by de novo recruitment of brown adipocytesCIN85 regulates dopamine receptor endocytosis and governs behaviour in miceInflammation and mitochondrial fatty acid beta-oxidation link obesity to early tumor promotionNeurobeachin, a regulator of synaptic protein targeting, is associated with body fat mass and feeding behavior in mice and body-mass index in humansA broad phenotypic screen identifies novel phenotypes driven by a single mutant allele in Huntington's disease CAG knock-in mice.Functional inactivation of the genome-wide association study obesity gene neuronal growth regulator 1 in mice causes a body mass phenotypeDll1 haploinsufficiency in adult mice leads to a complex phenotype affecting metabolic and immunological processeseIF6 coordinates insulin sensitivity and lipid metabolism by coupling translation to transcriptionRestless legs syndrome-associated intronic common variant in Meis1 alters enhancer function in the developing telencephalonDoes enamelin have pleiotropic effects on organs other than the teeth? Lessons from a phenotyping screen of two enamelin-mutant mouse linesLarge-scale phenotyping of an accurate genetic mouse model of JNCL identifies novel early pathology outside the central nervous systemLoss of the actin remodeler Eps8 causes intestinal defects and improved metabolic status in miceA humanized version of Foxp2 affects cortico-basal ganglia circuits in miceAnalysis of mammalian gene function through broad-based phenotypic screens across a consortium of mouse clinicsGeneration of mice lacking DUF1220 protein domains: effects on fecundity and hyperactivity.Pleiotropic functions for transcription factor zscan10.A comparative phenotypic and genomic analysis of C57BL/6J and C57BL/6N mouse strains.Requirement of the RNA-editing enzyme ADAR2 for normal physiology in miceThe German Mouse Clinic: a platform for systemic phenotype analysis of mouse models.Mouse phenotyping.Innovations in phenotyping of mouse models in the German Mouse Clinic.Rapamycin extends murine lifespan but has limited effects on aging.Mitochondrial dysfunction and decrease in body weight of a transgenic knock-in mouse model for TDP-43.Extensive phenotypic characterization of a new transgenic mouse reveals pleiotropic perturbations in physiology due to mesenchymal hGH minigene expression.Neuronal expression of glucosylceramide synthase in central nervous system regulates body weight and energy homeostasis.Defective lipolysis and altered energy metabolism in mice lacking adipose triglyceride lipase.Cardioprotection and lifespan extension by the natural polyamine spermidine.Standardized, systemic phenotypic analysis of Umod(C93F) and Umod(A227T) mutant mice.High fat diet-induced modifications in membrane lipid and mitochondrial-membrane protein signatures precede the development of hepatic insulin resistance in miceToxicity modelling of Plk1-targeted therapies in genetically engineered mice and cultured primary mammalian cells.Comparison of particle-exposure triggered pulmonary and systemic inflammation in mice fed with three different dietsFunctional compensation among HMGN variants modulates the DNase I hypersensitive sites at enhancersLong-term proteasomal inhibition in transgenic mice by UBB(+1) expression results in dysfunction of central respiration control reminiscent of brainstem neuropathology in Alzheimer patients.Cytochrome c oxidase subunit 4 isoform 2-knockout mice show reduced enzyme activity, airway hyporeactivity, and lung pathologyThe First Scube3 Mutant Mouse Line with Pleiotropic Phenotypic Alterations.Bezafibrate ameliorates diabetes via reduced steatosis and improved hepatic insulin sensitivity in diabetic TallyHo mice.A review of standardized metabolic phenotyping of animal models.The hepatic phosphatidylcholine transporter ABCB4 as modulator of glucose homeostasis.An intronic single base exchange leads to a brown adipose tissue-specific loss of Ucp3 expression and an altered body mass trajectory.Systemic first-line phenotyping.
P50
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P50
description
hulumtues
@sq
researcher
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wetenschapper
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հետազոտող
@hy
name
Jan Rozman
@ast
Jan Rozman
@en
Jan Rozman
@es
Jan Rozman
@nl
Jan Rozman
@sl
type
label
Jan Rozman
@ast
Jan Rozman
@en
Jan Rozman
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Jan Rozman
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Jan Rozman
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altLabel
Rozman J
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prefLabel
Jan Rozman
@ast
Jan Rozman
@en
Jan Rozman
@es
Jan Rozman
@nl
Jan Rozman
@sl
P1053
A-2540-2010
P106
P21
P31
P3829
P4012
P496
0000-0002-8035-8904