Predictions of BuChE inhibitors using support vector machine and naive Bayesian classification techniques in drug discovery.
about
MLViS: A Web Tool for Machine Learning-Based Virtual Screening in Early-Phase of Drug Discovery and DevelopmentBayesian models trained with HTS data for predicting β-haematin inhibition and in vitro antimalarial activity.AlzhCPI: A knowledge base for predicting chemical-protein interactions towards Alzheimer's disease.Three-Dimensional Biologically Relevant Spectrum (BRS-3D): Shape Similarity Profile Based on PDB Ligands as Molecular Descriptors.Predicting DPP-IV inhibitors with machine learning approaches.DL0410, a novel dual cholinesterase inhibitor, protects mouse brains against Aβ-induced neuronal damage via the Akt/JNK signaling pathway.In silico polypharmacology of natural products.Greedy and Linear Ensembles of Machine Learning Methods Outperform Single Approaches for QSPR Regression Problems.Molecular Modeling on Berberine Derivatives toward BuChE: An Integrated Study with Quantitative Structure-Activity Relationships Models, Molecular Docking, and Molecular Dynamics Simulations.Discovery of Influenza A virus neuraminidase inhibitors using support vector machine and Naïve Bayesian models.Predicting selective liver X receptor β agonists using multiple machine learning methods.Quantitative and Systems Pharmacology 3. Network-Based Identification of New Targets for Natural Products Enables Potential Uses in Aging-Associated Disorders.In silico prediction of ROCK II inhibitors by different classification approaches.Consensus models for CDK5 inhibitors in silico and their application to inhibitor discovery.Quantitative and Systems Pharmacology. 1. In Silico Prediction of Drug-Target Interactions of Natural Products Enables New Targeted Cancer Therapy.Evaluation of Novel Dual Acetyl- and Butyrylcholinesterase Inhibitors as Potential Anti-Alzheimer's Disease Agents Using Pharmacophore, 3D-QSAR, and Molecular Docking Approaches.Effects of P-Glycoprotein on the Transport of DL0410, a Potential Multifunctional Anti-Alzheimer Agent.DL0410 Ameliorates Memory and Cognitive Impairments Induced by Scopolamine via Increasing Cholinergic Neurotransmission in Mice.Design, Synthesis, and Biological Evaluation of a New Series of Biphenyl/Bibenzyl Derivatives Functioning as Dual Inhibitors of Acetylcholinesterase and Butyrylcholinesterase.LBVS: an online platform for ligand-based virtual screening using publicly accessible databases.TS-Chemscore, a Target-Specific Scoring Function, Significantly Improves the Performance of Scoring in Virtual Screening.Identification of Estrogen Receptor α Antagonists from Natural Products via In Vitro and In Silico Approaches.Computational Methodologies in the Exploration of Marine Natural Product Leads
P2860
Q28546859-2486F12F-53FD-473B-A07A-B1400DBA0047Q30883690-86651A3E-38AD-40FA-86D9-BACEAC0D45E6Q33769352-6A4B75E6-B585-42E9-90F3-2D92AB591C28Q36199304-7D966178-1167-44CB-9729-72AF453A954DQ36268544-324B4E27-AF93-4741-8258-818DD9DC4FAEQ37399395-3F58A394-D016-4895-AB0F-9C5FD9E4D408Q38810969-5E27C708-15D1-4C62-B6AA-F12DA5A705A4Q39525042-590D28E7-372E-4F12-94A2-0E1F19F0B284Q40230831-2F267451-6B7E-4EDB-B65A-B20E08E7C3F4Q41033255-999B89B6-B1F7-4384-BE04-B8226C764E55Q41312416-677FF2BD-7A17-4455-8A2A-23B851ABF4E9Q44424717-8B9A59AE-4CB3-4BC6-84E6-58C93B1B70E0Q45946417-6793A9C0-3F72-48A3-8620-06EA73E6447BQ45955634-6C31BD0B-23E5-42F3-A1E2-7CBE96D7CF89Q47731882-75F5C6DD-EE29-4F27-8113-737538715EC0Q47937308-998DEBFA-D0AE-4461-A800-75F1314E765DQ48173457-8CFC5A24-19D2-4D7A-9F03-167B64953A2DQ48273998-55A139F5-A085-4236-800F-54FBA58845D9Q48342566-009C6717-2A41-4A6C-B3C7-A94F685BC730Q50637160-64AFAA3A-3074-40F6-AFAE-64B65C8BD324Q51038790-0EDCDC6E-608A-4DD2-81F0-CB7862002509Q55207272-38D73E61-C0C3-4031-9F95-256002E06C50Q57001336-3AE96DAE-AF22-4639-AB7B-5AACE269C232
P2860
Predictions of BuChE inhibitors using support vector machine and naive Bayesian classification techniques in drug discovery.
description
2013 nî lūn-bûn
@nan
2013年の論文
@ja
2013年学术文章
@wuu
2013年学术文章
@zh
2013年学术文章
@zh-cn
2013年学术文章
@zh-hans
2013年学术文章
@zh-my
2013年学术文章
@zh-sg
2013年學術文章
@yue
2013年學術文章
@zh-hant
name
Predictions of BuChE inhibitor ...... techniques in drug discovery.
@en
Predictions of BuChE inhibitor ...... techniques in drug discovery.
@nl
type
label
Predictions of BuChE inhibitor ...... techniques in drug discovery.
@en
Predictions of BuChE inhibitor ...... techniques in drug discovery.
@nl
prefLabel
Predictions of BuChE inhibitor ...... techniques in drug discovery.
@en
Predictions of BuChE inhibitor ...... techniques in drug discovery.
@nl
P2093
P356
P1476
Predictions of BuChE inhibitor ...... techniques in drug discovery.
@en
P2093
Ai-Lin Liu
Guan-hua Du
Jiansong Fang
Ranyao Yang
Shengqian Yang
P304
P356
10.1021/CI400331P
P577
2013-11-06T00:00:00Z