Cytochrome P450 genetic polymorphisms and the response to prasugrel: relationship to pharmacokinetic, pharmacodynamic, and clinical outcomes.
about
Impact of selective platelet inhibition in reducing cardiovascular risk - role of vorapaxarThe pharmacogenetic control of antiplatelet response: candidate genes and CYP2C19Personalized antiplatelet and anticoagulation therapy: applications and significance of pharmacogenomicsPharmacogenomics and cardiovascular diseaseUp-Regulation of CYP2C19 Expression by BuChang NaoXinTong via PXR Activation in HepG2 CellsFuture translational applications from the contemporary genomics era: a scientific statement from the American Heart AssociationClopidogrel: the data, the experience, and the controversies.Use of genetic data to guide therapy in arterial disease.Integrated analysis of pharmacokinetic data across multiple clinical pharmacology studies of prasugrel, a new thienopyridine antiplatelet agent.Prasugrel vs. clopidogrel for cytochrome P450 2C19-genotyped subgroups: integration of the TRITON-TIMI 38 trial data.Potential Usefulness of Clopidogrel Pharmacogenetics in Cerebral Endovascular Procedures and Carotid Artery Stenting.Clinical pharmacogenetics implementation: approaches, successes, and challengesPantoprazole Does Not Reduce the Antiplatelet Effect of Clopidogrel: A Randomized Controlled Trial in KoreaGuided antithrombotic therapy: current status and future research direction: report on a National Heart, Lung and Blood Institute working group.Novel antiplatelet agents in the prevention of cardiovascular complications--focus on ticagrelor.Antiplatelet drug interactions with proton pump inhibitorsGenetic regulation of platelet receptor expression and function: application in clinical practice and drug development.Implementing genotype-guided antithrombotic therapy.Realities and expectations of pharmacogenomics and personalized medicine: impact of translating genetic knowledge into clinical practice.A case of resistance to clopidogrel and prasugrel after percutaneous coronary angioplasty.Pharmacogenetics and clopidogrel response in patients undergoing percutaneous coronary interventions.Cost-utility analysis of genotype-guided antiplatelet therapy in patients with moderate-to-high risk acute coronary syndrome and planned percutaneous coronary interventionInfluences of different proton pump inhibitors on the anti-platelet function of clopidogrel in relation to CYP2C19 genotypesEffects of cytochrome P450 2C19 and paraoxonase 1 polymorphisms on antiplatelet response to clopidogrel therapy in patients with coronary artery diseaseCurrent concepts on antiplatelet therapy: focus on the novel thienopyridine and non-thienopyridine agents.Clinical importance of aspirin and clopidogrel resistanceGenetic variants in ABCB1 and CYP2C19 and cardiovascular outcomes after treatment with clopidogrel and prasugrel in the TRITON-TIMI 38 trial: a pharmacogenetic analysisAn algorithm for use of prasugrel (effient) in patients undergoing cardiac catheterization and percutaneous coronary intervention.Understanding the economic value of molecular diagnostic tests: case studies and lessons learned.Reduced-function CYP2C19 genotype and risk of adverse clinical outcomes among patients treated with clopidogrel predominantly for PCI: a meta-analysis.Genetic heterogeneity beyond CYP2C8*3 does not explain differential sensitivity to paclitaxel-induced neuropathy.Pharmacogenomics: the genetics of variable drug responses.Indirect estimation of the comparative treatment effect in pharmacogenomic subgroups.Routine screening for CYP2C19 polymorphisms for patients being treated with clopidogrel is not recommendedStructure, function, regulation and polymorphism and the clinical significance of human cytochrome P450 1A2.Clinical evidence of interaction between clopidogrel and proton pump inhibitorsHumanizing thrombi in mice.Oral antiplatelet therapy in diabetes mellitus and the role of prasugrel: an overview.Cardiovascular pharmacogenomicsClinical Pharmacogenetics Implementation Consortium guidelines for cytochrome P450-2C19 (CYP2C19) genotype and clopidogrel therapy.
P2860
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P2860
Cytochrome P450 genetic polymorphisms and the response to prasugrel: relationship to pharmacokinetic, pharmacodynamic, and clinical outcomes.
description
2009 nî lūn-bûn
@nan
2009年の論文
@ja
2009年学术文章
@wuu
2009年学术文章
@zh
2009年学术文章
@zh-cn
2009年学术文章
@zh-hans
2009年学术文章
@zh-my
2009年学术文章
@zh-sg
2009年學術文章
@yue
2009年學術文章
@zh-hant
name
Cytochrome P450 genetic polymo ...... ynamic, and clinical outcomes.
@en
Cytochrome P450 genetic polymo ...... ynamic, and clinical outcomes.
@nl
type
label
Cytochrome P450 genetic polymo ...... ynamic, and clinical outcomes.
@en
Cytochrome P450 genetic polymo ...... ynamic, and clinical outcomes.
@nl
prefLabel
Cytochrome P450 genetic polymo ...... ynamic, and clinical outcomes.
@en
Cytochrome P450 genetic polymo ...... ynamic, and clinical outcomes.
@nl
P2093
P1433
P1476
Cytochrome P450 genetic polymo ...... ynamic, and clinical outcomes.
@en
P2093
Jessica L Mega
John T Brandt
Joseph R Walker
Marc S Sabatine
Richard D Hockett
Sandra L Close
Stephen D Wiviott
William L Macias
P304
P356
10.1161/CIRCULATIONAHA.109.851949
P407
P577
2009-05-04T00:00:00Z