Influence of adenoviral fiber mutations on viral encapsidation, infectivity and in vivo tropism.
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A comparison of efficacy and toxicity between electroporation and adenoviral gene transferAdenovirus Binding to Blood Factors Results in Liver Cell Infection and HepatotoxicityProtein crystals in Adenovirus type 5-infected cells: requirements for intranuclear crystallogenesis, structural and functional analysisDefining a Novel Role for the Coxsackievirus and Adenovirus Receptor in Human Adenovirus Serotype 5 Transduction In Vitro in the Presence of Mouse Serum.Peptide-based technologies to alter adenoviral vector tropism: ways and means for systemic treatment of cancerAdenovirus receptors.Influence of fiber detargeting on adenovirus-mediated innate and adaptive immune activationAdenovirus receptors and their implications in gene deliveryReduction of natural adenovirus tropism to mouse liver by fiber-shaft exchange in combination with both CAR- and alphav integrin-binding ablation.Subgroup B and F fiber chimeras eliminate normal adenovirus type 5 vector transduction in vitro and in vivo.Reduction of natural adenovirus tropism to the liver by both ablation of fiber-coxsackievirus and adenovirus receptor interaction and use of replaceable short fiber.Adenovirus serotype 5 vectors with Tat-PTD modified hexon and serotype 35 fiber show greatly enhanced transduction capacity of primary cell cultures.Mutation in fiber of adenovirus serotype 5 gene therapy vector decreases liver tropism.A mouse model for HIV-1 entryReduced infectivity of adenovirus type 5 particles and degradation of entering viral genomes associated with incomplete processing of the preterminal protein.Novel vectors for in vivo gene delivery to vascular tissue.Ephrin A2 receptor targeting does not increase adenoviral pancreatic cancer transduction in vivo.Targeting of adenovirus serotype 5 pseudotyped with short fiber from serotype 41 to c-erbB2-positive cells using bispecific single-chain diabody.The importance of coagulation factors binding to adenovirus: historical perspectives and implications for gene delivery.Tropism-modification strategies for targeted gene delivery using adenoviral vectors.Redirecting adenovirus tropism by genetic, chemical, and mechanical modification of the adenovirus surface for cancer gene therapy.Sstr2A: a relevant target for the delivery of genes into human glioblastoma cells using fiber-modified adenoviral vectors.Targeting adenoviral vectors by using the extracellular domain of the coxsackie-adenovirus receptor: improved potency via trimerization.Integrin alphavbeta5 is a primary receptor for adenovirus in CAR-negative cells.Tropism modification of adenovirus vectors by peptide ligand insertion into various positions of the adenovirus serotype 41 short-fiber knob domain.Genetic manipulations of adenovirus type 5 fiber resulting in liver tropism attenuation.CAR- or alphav integrin-binding ablated adenovirus vectors, but not fiber-modified vectors containing RGD peptide, do not change the systemic gene transfer properties in mice.Analysis of adenovirus sequestration in the liver, transduction of hepatic cells, and innate toxicity after injection of fiber-modified vectorsSignificant alterations of biodistribution and immune responses in Balb/c mice administered with adenovirus targeted to CD40(+) cells.Gene Targeting to the Uteroplacental Circulation of Pregnant Guinea Pigs.Structural and mutational analysis of human Ad37 and canine adenovirus 2 fiber heads in complex with the D1 domain of coxsackie and adenovirus receptor.
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P2860
Influence of adenoviral fiber mutations on viral encapsidation, infectivity and in vivo tropism.
description
2001 nî lūn-bûn
@nan
2001年の論文
@ja
2001年学术文章
@wuu
2001年学术文章
@zh
2001年学术文章
@zh-cn
2001年学术文章
@zh-hans
2001年学术文章
@zh-my
2001年学术文章
@zh-sg
2001年學術文章
@yue
2001年學術文章
@zh-hant
name
Influence of adenoviral fiber ...... fectivity and in vivo tropism.
@en
Influence of adenoviral fiber ...... fectivity and in vivo tropism.
@nl
type
label
Influence of adenoviral fiber ...... fectivity and in vivo tropism.
@en
Influence of adenoviral fiber ...... fectivity and in vivo tropism.
@nl
prefLabel
Influence of adenoviral fiber ...... fectivity and in vivo tropism.
@en
Influence of adenoviral fiber ...... fectivity and in vivo tropism.
@nl
P2093
P2860
P356
P1433
P1476
Influence of adenoviral fiber ...... fectivity and in vivo tropism.
@en
P2093
Leissner P
Pavirani A
Schlesinger Y
P2860
P2888
P356
10.1038/SJ.GT.3301343
P577
2001-01-01T00:00:00Z
P5875
P6179
1044372868