Acylation of lysine 983 is sufficient for toxin activity of Bordetella pertussis adenylate cyclase. Substitutions of alanine 140 modulate acylation site selectivity of the toxin acyltransferase CyaC.
about
Molecular pathogenesis, epidemiology, and clinical manifestations of respiratory infections due to Bordetella pertussis and other Bordetella subspecies.RTX proteins: a highly diverse family secreted by a common mechanismMARTX toxins as effector delivery platformsFine Epitope Mapping of Two Antibodies Neutralizing the Bordetella Adenylate Cyclase Toxin.The Bordetella adenylate cyclase repeat-in-toxin (RTX) domain is immunodominant and elicits neutralizing antibodies.Differences in purinergic amplification of osmotic cell lysis by the pore-forming RTX toxins Bordetella pertussis CyaA and Actinobacillus pleuropneumoniae ApxIA: the role of pore size.Selective translocation of the Bordetella pertussis adenylate cyclase toxin across the basolateral membranes of polarized epithelial cellsMembrane restructuring by Bordetella pertussis adenylate cyclase toxin, a member of the RTX toxin family.Structural Characterization of Humanized Nanobodies with Neutralizing Activity against the Bordetella pertussis CyaA-Hemolysin: Implications for a Potential Epitope of Toxin-Protective AntigenAcyltransferases in bacteria.Pore-forming and enzymatic activities of Bordetella pertussis adenylate cyclase toxin synergize in promoting lysis of monocytes.The conserved tyrosine residue 940 plays a key structural role in membrane interaction of Bordetella adenylate cyclase toxin.Interaction of Bordetella pertussis adenylate cyclase with CD11b/CD18: Role of toxin acylation and identification of the main integrin interaction domain.Structure-Function Relationships Underlying the Capacity of Bordetella Adenylate Cyclase Toxin to Disarm Host Phagocytes.The Neisseria meningitidis outer membrane lipoprotein FrpD binds the RTX protein FrpC.Characterization of Post-Translational Modifications and Cytotoxic Properties of the Adenylate-Cyclase Hemolysin Produced by Various Bordetella pertussis and Bordetella parapertussis Isolates.Binding of Escherichia coli hemolysin and activation of the target cells is not receptor-dependent.Membrane-Active Properties of an Amphitropic Peptide from the CyaA Toxin Translocation Region.Membrane localization of the Repeats-in-Toxin (RTX) Leukotoxin (LtxA) produced by Aggregatibacter actinomycetemcomitans
P2860
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P2860
Acylation of lysine 983 is sufficient for toxin activity of Bordetella pertussis adenylate cyclase. Substitutions of alanine 140 modulate acylation site selectivity of the toxin acyltransferase CyaC.
description
2001 nî lūn-bûn
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2001年の論文
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2001年学术文章
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2001年学术文章
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2001年学术文章
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name
Acylation of lysine 983 is suf ...... he toxin acyltransferase CyaC.
@en
Acylation of lysine 983 is suf ...... he toxin acyltransferase CyaC.
@nl
type
label
Acylation of lysine 983 is suf ...... he toxin acyltransferase CyaC.
@en
Acylation of lysine 983 is suf ...... he toxin acyltransferase CyaC.
@nl
prefLabel
Acylation of lysine 983 is suf ...... he toxin acyltransferase CyaC.
@en
Acylation of lysine 983 is suf ...... he toxin acyltransferase CyaC.
@nl
P2093
P2860
P356
P1476
Acylation of lysine 983 is suf ...... the toxin acyltransferase CyaC
@en
P2093
P2860
P304
P356
10.1074/JBC.M006463200
P407
P50
P577
2001-01-01T00:00:00Z