Calpain inhibitor I reduces the activation of nuclear factor-kappaB and organ injury/dysfunction in hemorrhagic shock. - Wikidata - awgldk - TriplyDB

Calpain inhibitor I reduces the activation of nuclear factor-kappaB and organ injury/dysfunction in hemorrhagic shock.

Calpain inhibitor I reduces the activation of nuclear factor-kappaB and organ injury/dysfunction in hemorrhagic shock.

http://www.wikidata.org/entity/Q43517281

about

Lung injury after hemorrhage is age dependent: role of peroxisome proliferator-activated receptor gamma Over-expression of calpastatin inhibits calpain activation and attenuates myocardial dysfunction during endotoxaemia Glucosamine improves cardiac function following trauma-hemorrhage by increased protein O-GlcNAcylation and attenuation of NF-{kappa}B signaling Toll-like receptor 4 plays a central role in cardiac dysfunction during trauma hemorrhage shock Moderation of calpain activity promotes neovascular integration and lumen formation during VEGF-induced pathological angiogenesis Pyrrolidine dithiocarbamate attenuates the development of acute and chronic inflammation.Protective effect of calpain inhibitor N-acetyl-L-leucyl-L-leucyl-L-norleucinal on acute alcohol consumption related cardiomyopathy.Nicotinic acetylcholine receptor α1 promotes calpain-1 activation and macrophage inflammation in hypercholesterolemic nephropathy Calpain inhibition attenuates angiotensin II-induced abdominal aortic aneurysms and atherosclerosis in low-density lipoprotein receptor-deficient mice.Calpastatin controls polymicrobial sepsis by limiting procoagulant microparticle release Inhibition of IκB Kinase Attenuates the Organ Injury and Dysfunction Associated with Hemorrhagic Shock Activation of Both the Calpain and Ubiquitin-Proteasome Systems Contributes to Septic Cardiomyopathy through Dystrophin Loss/Disruption and mTOR Inhibition Calpain inhibition improves collateral-dependent perfusion in a hypercholesterolemic swine model of chronic myocardial ischemia.Ischemia-reperfusion injury in rat steatotic liver is dependent on NFκB P65 activation Late intervention with the small molecule BB3 mitigates postischemic kidney injury.Protective effects of PARP inhibitor, PJ34, is related to down-regulation of calpain and NF-κB in a mouse model of TBI.Effect and mechanism of calpains on pediatric lobar pneumonia.Activation of calpains mediates early lung neutrophilic inflammation in ventilator-induced lung injury.Inhibit the calpain to climb the mountain.Protective Effects of Calpain Inhibition on Neurovascular Unit Injury through Downregulating Nuclear Factor-κB-related Inflammation during Traumatic Brain Injury in Mice.Selective melanocortin MC4 receptor agonists reverse haemorrhagic shock and prevent multiple organ damage.Calpain inhibitor I and colonic inflammation induced by DNBS in the rat.Peptidyl alpha-keto amide inhibitor of calpain blocks excitotoxic damage without affecting signal transduction events.Attenuation of neutrophil-mediated myocardial ischemia-reperfusion injury by a calpain inhibitor.Endoplasmic reticulum Ca(2+) signaling and calpains mediate renal cell death.Ethyl pyruvate modulates inflammatory gene expression in mice subjected to hemorrhagic shock.Calpains mediate p53 activation and neuronal death evoked by DNA damage.In vivo calpain/caspase cross-talk during 3-nitropropionic acid-induced striatal degeneration: implication of a calpain-mediated cleavage of active caspase-3.Na+/H+ exchanger is required for hyperglycaemia-induced endothelial dysfunction via calcium-dependent calpain.Application of normobaric hyperoxia therapy for amelioration of haemorrhagic shock-induced acute renal failure.Prenatal alcohol-induced neuroapoptosis in rat brain cerebral cortex: protective effect of folic acid and betaine.Altered inflammatory gene expression underlies increased susceptibility to murine postoperative ileus with advancing age.The investigation of the prenatal and postnatal alcohol exposure-induced neurodegeneration in rat brain: protection by betaine and/or omega-3.Calpain inhibition attenuates iNOS production and midzonal hepatic necrosis in a repeat dose model of endotoxemia in rats.Effects of a Single Dose of Parecoxib on Inflammatory Response and Ischemic Tubular Injury Caused by Hemorrhagic Shock in Rats.

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Calpain inhibitor I reduces the activation of nuclear factor-kappaB and organ injury/dysfunction in hemorrhagic shock.

http://www.wikidata.org/entity/Q43517281

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2001 nî lūn-bûn

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Calpain inhibitor I reduces th ...... function in hemorrhagic shock.

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Calpain inhibitor I reduces th ...... function in hemorrhagic shock.

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Abdelrahman M

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Chatterjee PK

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Cuzzocrea S

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Harwood S

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McDonald MC

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Paul A

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Plevin R

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171-186

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10.1096/FJ.99-0645COM

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1

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Helder Mota-Filipe

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