Protective effect of shikonin in experimental ischemic stroke: attenuated TLR4, p-p38MAPK, NF-κB, TNF-α and MMP-9 expression, up-regulated claudin-5 expression, ameliorated BBB permeability.
about
Biosynthesis and molecular actions of specialized 1,4-naphthoquinone natural products produced by horticultural plantsAnti-Inflammatory Effects of Traditional Chinese Medicines against Ischemic Injury in In Vivo Models of Cerebral IschemiaPotential of Pseudoshikonin I Isolated from Lithospermi Radix as Inhibitors of MMPs in IL-1β-Induced SW1353 CellsShikonin Isolated from Lithospermum erythrorhizon Downregulates Proinflammatory Mediators in Lipopolysaccharide-Stimulated BV2 Microglial Cells by Suppressing Crosstalk between Reactive Oxygen Species and NF-κB.Ferulic Acid Administered at Various Time Points Protects against Cerebral Infarction by Activating p38 MAPK/p90RSK/CREB/Bcl-2 Anti-Apoptotic Signaling in the Subacute Phase of Cerebral Ischemia-Reperfusion Injury in RatsEffects of Etanercept against Transient Cerebral Ischemia in Diabetic Rats.One-Compound-Multi-Target: Combination Prospect of Natural Compounds with Thrombolytic Therapy in Acute Ischemic Stroke.The protective effects of shikonin on hepatic ischemia/reperfusion injury are mediated by the activation of the PI3K/Akt pathway.Potential medications or compounds acting on toll-like receptors in cerebral ischemia.Tissue kallikrein protects against ischemic stroke by suppressing TLR4/NF-κB and activating Nrf2 signaling pathway in ratsProtective effect of Spatholobus suberectus on brain tissues in cerebral ischemia.Remodeling the blood-brain barrier microenvironment by natural products for brain tumor therapy.Identification of autophagy signaling network that contributes to stroke in the ischemic rodent brain via gene expressionDisruption of blood-brain barrier integrity in postmortem alcoholic brain: preclinical evidence of TLR4 involvement from a binge-like drinking model.Shikonin protects against D-Galactosamine and lipopolysaccharide-induced acute hepatic injury by inhibiting TLR4 signaling pathway.Therapeutic Effect of Vinorine on Sciatic Nerve Injured Rat.Shikonin inhibits myeloid differentiation protein-2 to prevent lipopolysaccharide-induced acute lung injury.Remote limb ischemic postconditioning protects mouse brain against cerebral ischemia/reperfusion injury via upregulating expression of Nrf2, HO-1 and NQO-1 in mice.Ulinastatin downregulates TLR4 and NF-kB expression and protects mouse brains against ischemia/reperfusion injury.Penehyclidine hydrochloride inhibits TLR4 signaling and inflammation, and attenuates blunt chest trauma and hemorrhagic shock-induced acute lung injury in rats.Protective effect of naringenin in experimental ischemic stroke: down-regulated NOD2, RIP2, NF-κB, MMP-9 and up-regulated claudin-5 expression.Loss of connexin43 in murine Sertoli cells and its effect on blood-testis barrier formation and dynamics.Natural products: a hope for glioblastoma patients.
P2860
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P2860
Protective effect of shikonin in experimental ischemic stroke: attenuated TLR4, p-p38MAPK, NF-κB, TNF-α and MMP-9 expression, up-regulated claudin-5 expression, ameliorated BBB permeability.
description
2013 nî lūn-bûn
@nan
2013年の論文
@ja
2013年学术文章
@wuu
2013年学术文章
@zh
2013年学术文章
@zh-cn
2013年学术文章
@zh-hans
2013年学术文章
@zh-my
2013年学术文章
@zh-sg
2013年學術文章
@yue
2013年學術文章
@zh-hant
name
Protective effect of shikonin ...... ameliorated BBB permeability.
@en
Protective effect of shikonin ...... ameliorated BBB permeability.
@nl
type
label
Protective effect of shikonin ...... ameliorated BBB permeability.
@en
Protective effect of shikonin ...... ameliorated BBB permeability.
@nl
prefLabel
Protective effect of shikonin ...... ameliorated BBB permeability.
@en
Protective effect of shikonin ...... ameliorated BBB permeability.
@nl
P2093
P2860
P921
P1476
Protective effect of shikonin ...... ameliorated BBB permeability.
@en
P2093
Chunhua Zhu
Huimin Qiao
Jiangyong Miao
Linyu Chen
Sheng Wang
Xiangjian Zhang
Zhenzhong Li
P2860
P2888
P304
P356
10.1007/S11064-013-1194-X
P577
2013-11-19T00:00:00Z
P5875
P6179
1003647854