Role of type II thioesterases: evidence for removal of short acyl chains produced by aberrant decarboxylation of chain extender units.
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Giant plasmid-encoded polyketide synthases produce the macrolide toxin of Mycobacterium ulceransCharacterization of the biosynthesis gene cluster for the pyrrole polyether antibiotic calcimycin (A23187) in Streptomyces chartreusis NRRL 3882Structure and Functional Analysis of RifR, the Type II Thioesterase from the Rifamycin Biosynthetic PathwayStructure and Catalytic Mechanism of the Thioesterase CalE7 in Enediyne BiosynthesisStructure and Function of the RedJ Protein, a Thioesterase from the Prodiginine Biosynthetic Pathway in Streptomyces coelicolorA labile point in mutant amphotericin polyketide synthasesPchC thioesterase optimizes nonribosomal biosynthesis of the peptide siderophore pyochelin in Pseudomonas aeruginosaCloning, sequencing, and functional analysis of an iterative type I polyketide synthase gene cluster for biosynthesis of the antitumor chlorinated polyenone neocarzilin in "Streptomyces carzinostaticus"Cloning and characterization of the pyrrolomycin biosynthetic gene clusters from Actinosporangium vitaminophilum ATCC 31673 and Streptomyces sp. strain UC 11065Characterization of the 'pristinamycin supercluster' of Streptomyces pristinaespiralis.Insights into the complex biosynthesis of the leupyrrins in Sorangium cellulosum So ce690.A late-stage intermediate in salinomycin biosynthesis is revealed by specific mutation in the biosynthetic gene cluster.Roles of type II thioesterases and their application for secondary metabolite yield improvement.Process and metabolic strategies for improved production of Escherichia coli-derived 6-deoxyerythronolide B.Regeneration of misprimed nonribosomal peptide synthetases by type II thioesterases.Identification of nocobactin NA biosynthetic gene clusters in Nocardia farcinica.Functional analysis of filipin tailoring genes from Streptomyces filipinensis reveals alternative routes in filipin III biosynthesis and yields bioactive derivativesCharacterization of the bafilomycin biosynthetic gene cluster from Streptomyces lohii.Comparative characterization of the lactimidomycin and iso-migrastatin biosynthetic machineries revealing unusual features for acyltransferase-less type I polyketide synthases and providing an opportunity to engineer new analogues.Inactivation of tesA reduces cell wall lipid production and increases drug susceptibility in mycobacteria.The enzymology of combinatorial biosynthesis.Interrogation of global active site occupancy of a fungal iterative polyketide synthase reveals strategies for maintaining biosynthetic fidelity.Characterization of a gene cluster responsible for the biosynthesis of anticancer agent FK228 in Chromobacterium violaceum No. 968Polyketide proofreading by an acyltransferase-like enzyme.The biosynthesis, molecular genetics and enzymology of the polyketide-derived metabolites.Polyketide Ring Expansion Mediated by a Thioesterase, Chain Elongation and Cyclization Domain, in Azinomycin Biosynthesis: Characterization of AziB and AziG.Selective removal of aberrant extender units by a type II thioesterase for efficient FR-008/candicidin biosynthesis in Streptomyces sp. strain FR-008.Characterization of the complete zwittermicin A biosynthesis gene cluster from Bacillus cereusMycolactones: immunosuppressive and cytotoxic polyketides produced by aquatic mycobacteria.Structural insights into nonribosomal peptide enzymatic assembly linesiso-Migrastatin, migrastatin, and dorrigocin production in Streptomyces platensis NRRL 18993 is governed by a single biosynthetic machinery featuring an acyltransferase-less type I polyketide synthase.Polyketide stereocontrol: a study in chemical biology.PKS and NRPS release mechanisms.Thioesterases: a new perspective based on their primary and tertiary structures.Iterative type I polyketide synthases involved in enediyne natural product biosynthesis.Uncovering the structures of modular polyketide synthases.Policing starter unit selection of the enterocin type II polyketide synthase by the type II thioesterase EncL.Polyketide synthase and non-ribosomal peptide synthetase thioesterase selectivity: logic gate or a victim of fate?Structure and Functional Analysis of ClbQ, an Unusual Intermediate-Releasing Thioesterase from the Colibactin Biosynthetic Pathway.Biosynthesis of polyketides by trans-AT polyketide synthases.
P2860
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P2860
Role of type II thioesterases: evidence for removal of short acyl chains produced by aberrant decarboxylation of chain extender units.
description
2001 nî lūn-bûn
@nan
2001年の論文
@ja
2001年学术文章
@wuu
2001年学术文章
@zh
2001年学术文章
@zh-cn
2001年学术文章
@zh-hans
2001年学术文章
@zh-my
2001年学术文章
@zh-sg
2001年學術文章
@yue
2001年學術文章
@zh-hant
name
Role of type II thioesterases: ...... ation of chain extender units.
@en
Role of type II thioesterases: ...... ation of chain extender units.
@nl
type
label
Role of type II thioesterases: ...... ation of chain extender units.
@en
Role of type II thioesterases: ...... ation of chain extender units.
@nl
prefLabel
Role of type II thioesterases: ...... ation of chain extender units.
@en
Role of type II thioesterases: ...... ation of chain extender units.
@nl
P1476
Role of type II thioesterases: ...... ation of chain extender units.
@en
P2093
Heathcote ML
Staunton J
P304
P356
10.1016/S1074-5521(01)00002-3
P577
2001-02-01T00:00:00Z