Expression of herpes simplex virus-thymidine kinase gene controlled by a promoter region of the midkine gene confers selective cytotoxicity to ganciclovir in human carcinoma cells.

Expression of herpes simplex virus-thymidine kinase gene controlled by a promoter region of the midkine gene confers selective cytotoxicity to ganciclovir in human carcinoma cells.

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http://www.wikidata.org/entity/Q43553564
Inhibition of the growth factor MDK/midkine by a novel small molecule compound to treat non-small cell lung cancerMesenchymal stem cells are efficiently transduced with adenoviruses bearing type 35-derived fibers and the transduced cells with the IL-28A gene produces cytotoxicity to lung carcinoma cells co-cultured.Folate-linked nanoparticle-mediated suicide gene therapy in human prostate cancer and nasopharyngeal cancer with herpes simplex virus thymidine kinase.Cytotoxic effects of replication-competent adenoviruses on human esophageal carcinoma are enhanced by forced p53 expression.A promoter region of the midkine gene that is frequently expressed in human hepatocellular carcinoma can activate a suicide gene as effectively as the alpha-fetoprotein promoter.Midkine translocated to nucleoli and involved in carcinogenesis.Replication-competent adenoviruses with the type 35-derived fiber-knob region achieve reactive oxygen species-dependent cytotoxicity and produce greater toxicity than those with the type 5-derived region in pancreatic carcinoma.Expression of p53 synergistically augments caspases-mediated apoptosis induced by replication-competent adenoviruses in pancreatic carcinoma cells.Cytotoxicity of replication-competent adenoviruses powered by an exogenous regulatory region is not linearly correlated with the viral infectivity/gene expression or with the E1A-activating ability but is associated with the p53 genotypes.Liposome vector containing biosurfactant-complexed DNA as herpes simplex virus thymidine kinase gene delivery system.Suicide gene therapy of sarcoma cell lines using recombinant adeno-associated virus 2 vectors.A combinatory use of adenoviruses expressing melanoma differentiation-associated gene-7 and replication-competent adenoviruses produces synergistic effects on pancreatic carcinoma cells.An image cytometric technique is a concise method to detect adenoviruses and host cell proteins and to monitor the infection and cellular responses induced.
P2860

Expression of herpes simplex virus-thymidine kinase gene controlled by a promoter region of the midkine gene confers selective cytotoxicity to ganciclovir in human carcinoma cells.

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http://www.wikidata.org/entity/Q43553564
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2001 nî lūn-bûn
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2001年の論文
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name
Expression of herpes simplex v ...... ovir in human carcinoma cells.
@en
Expression of herpes simplex v ...... ovir in human carcinoma cells.
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type
label
Expression of herpes simplex v ...... ovir in human carcinoma cells.
@en
Expression of herpes simplex v ...... ovir in human carcinoma cells.
@nl
prefLabel
Expression of herpes simplex v ...... ovir in human carcinoma cells.
@en
Expression of herpes simplex v ...... ovir in human carcinoma cells.
@nl
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Expression of herpes simplex v ...... ovir in human carcinoma cells.
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P2093
P2860
P304
P31
P356
10.1002/1097-0215(200002)9999:9999<::AID-IJC1112>3.0.CO;2-X
P433
P478
P577
P698
P921