Lack of correlation between in vitro inhibition of CYP3A-mediated metabolism by a PPAR-gamma agonist and its effect on the clinical pharmacokinetics of midazolam, an in vivo probe of CYP3A activity.
about
Pharmacologic and genetic manipulation of MMP-2 and -9 affects retinal neovascularization in rodent models of OIR.Lack of effect of subject posture on intravenous midazolam clearance: implications for hepatic cytochrome P450 3A phenotyping.Differences in cytochrome p450-mediated pharmacokinetics between chinese and caucasian populations predicted by mechanistic physiologically based pharmacokinetic modelling.Limited sampling models for oral midazolam: midazolam plasma concentrations, not the ratio of 1-hydroxymidazolam to midazolam plasma concentrations, accurately predicts AUC as a biomarker of CYP3A activity.Method for predicting the risk of drug-drug interactions involving inhibition of intestinal CYP3A4 and P-glycoprotein.Sources of interindividual variability in IVIVE of clearance: an investigation into the prediction of benzodiazepine clearance using a mechanistic population-based pharmacokinetic model.
P2860
Lack of correlation between in vitro inhibition of CYP3A-mediated metabolism by a PPAR-gamma agonist and its effect on the clinical pharmacokinetics of midazolam, an in vivo probe of CYP3A activity.
description
2001 nî lūn-bûn
@nan
2001年の論文
@ja
2001年学术文章
@wuu
2001年学术文章
@zh-cn
2001年学术文章
@zh-hans
2001年学术文章
@zh-my
2001年学术文章
@zh-sg
2001年學術文章
@yue
2001年學術文章
@zh
2001年學術文章
@zh-hant
name
Lack of correlation between in ...... vivo probe of CYP3A activity.
@en
Lack of correlation between in ...... vivo probe of CYP3A activity.
@nl
type
label
Lack of correlation between in ...... vivo probe of CYP3A activity.
@en
Lack of correlation between in ...... vivo probe of CYP3A activity.
@nl
prefLabel
Lack of correlation between in ...... vivo probe of CYP3A activity.
@en
Lack of correlation between in ...... vivo probe of CYP3A activity.
@nl
P2093
P2860
P1476
Lack of correlation between in ...... vivo probe of CYP3A activity.
@en
P2093
P2860
P304
P356
10.1177/00912700122010122
P577
2001-03-01T00:00:00Z