Two distinct pathways for cAMP-mediated down-regulation of the beta 2-adrenergic receptor. Phosphorylation of the receptor and regulation of its mRNA level.
about
Nedd4 mediates agonist-dependent ubiquitination, lysosomal targeting, and degradation of the beta2-adrenergic receptorDown-regulation of the alpha-2C adrenergic receptor: involvement of a serine/threonine motif in the third cytoplasmic loopA dynamic interface between ubiquitylation and cAMP signalingNon-monotonic dose-response relationships and endocrine disruptors: a qualitative method of assessmentMolecular cloning of a rat kappa opioid receptor reveals sequence similarities to the mu and delta opioid receptorsCargo-mediated regulation of a rapid Rab4-dependent recycling pathwayRole of beta-arrestin1/ERK MAP kinase pathway in regulating adenosine A1 receptor desensitization and recovery.Involvement of tyrosine residues located in the carboxyl tail of the human beta 2-adrenergic receptor in agonist-induced down-regulation of the receptorAlpha 1-adrenergic receptor mRNA level is regulated by norepinephrine in rabbit aortic smooth muscle cells.Agonists induce conformational changes in transmembrane domains III and VI of the beta2 adrenoceptorAltered phosphorylation and desensitization patterns of a human beta 2-adrenergic receptor lacking the palmitoylated Cys341.Paradoxical attenuation of β2-AR function in airway smooth muscle by Gi-mediated counterregulation in transgenic mice overexpressing type 5 adenylyl cyclase.MicroRNA let-7 establishes expression of beta2-adrenergic receptors and dynamically down-regulates agonist-promoted down-regulation.In vitro mutagenesis and the search for structure-function relationships among G protein-coupled receptorsPhosphorylation of the deubiquitinase USP20 by protein kinase A regulates post-endocytic trafficking of β2 adrenergic receptors to autophagosomes during physiological stress.Molecular biology and respiratory disease. 5. Molecular biology of receptors: implications for lung disease.Structural basis for receptor subtype-specific regulation revealed by a chimeric beta 3/beta 2-adrenergic receptor.Structure, function, and regulation of adrenergic receptors.Long-term agonist exposure induces upregulation of beta 3-adrenergic receptor expression via multiple cAMP response elements.Regulation of muscarinic acetylcholine receptor mRNA expression by activation of homologous and heterologous receptors.Targeted transgenesis reveals discrete attenuator functions of GRK and PKA in airway beta2-adrenergic receptor physiologic signalingTranscription mediated by a cAMP-responsive promoter element is reduced upon activation of dopamine D2 receptors.Beta-Adrenergic AgonistsDual regulation of β2-adrenoceptor messenger RNA expression in human lung fibroblasts by β2-cAMP signaling; delayed upregulated inhibitors oppose a rapid in onset, direct stimulation of gene expression.GPCR desensitization: Acute and prolonged phases.Functional effects of long-term activation on human beta 2- and beta 3-adrenoceptor signallingRegulatory mechanisms that modulate signalling by G-protein-coupled receptors.Modulation in vivo of beta-adrenergic-receptor subtypes in rat brown adipose tissue by the thermogenic agonist Ro 16-8714.Synthetic peptides of the hamster beta 2-adrenoceptor as substrates and inhibitors of the beta-adrenoceptor kinase.Benzo(a)pyrene triggers desensitization of β2-adrenergic pathway.β2-Adrenergic receptor desensitization in perirenal adipose tissue in fetuses and lambs with placental insufficiency-induced intrauterine growth restriction.A CREB-mediated increase in miRNA let-7f during prolonged β-agonist exposure: a novel mechanism of β2-adrenergic receptor down-regulation in airway smooth muscle.
P2860
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P2860
Two distinct pathways for cAMP-mediated down-regulation of the beta 2-adrenergic receptor. Phosphorylation of the receptor and regulation of its mRNA level.
description
1989 nî lūn-bûn
@nan
1989年の論文
@ja
1989年学术文章
@wuu
1989年学术文章
@zh
1989年学术文章
@zh-cn
1989年学术文章
@zh-hans
1989年学术文章
@zh-my
1989年学术文章
@zh-sg
1989年學術文章
@yue
1989年學術文章
@zh-hant
name
Two distinct pathways for cAMP ...... regulation of its mRNA level.
@en
Two distinct pathways for cAMP ...... regulation of its mRNA level.
@nl
type
label
Two distinct pathways for cAMP ...... regulation of its mRNA level.
@en
Two distinct pathways for cAMP ...... regulation of its mRNA level.
@nl
prefLabel
Two distinct pathways for cAMP ...... regulation of its mRNA level.
@en
Two distinct pathways for cAMP ...... regulation of its mRNA level.
@nl
P2093
P1476
Two distinct pathways for cAMP ...... regulation of its mRNA level.
@en
P2093
Campbell PT
Kobilka BK
Lefkowitz RJ
MacGregor C
de Blasi A
P304
16786-16792
P407
P577
1989-10-01T00:00:00Z