A central functional role for the 49-kDa subunit within the catalytic core of mitochondrial complex I.
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Structural Basis for the Mechanism of Respiratory Complex ICrystal structure of the entire respiratory complex IHow the structure of the large subunit controls function in an oxygen-tolerant [NiFe]-hydrogenaseStructural biology. Mechanistic insight from the crystal structure of mitochondrial complex IA simple energy-conserving system: Proton reduction coupled to proton translocationTowards the molecular mechanism of respiratory complex I.Sodium ion cycling mediates energy coupling between complex I and ATP synthase.Proton pumping by NADH:ubiquinone oxidoreductase. A redox driven conformational change mechanism?Isoflurane selectively inhibits distal mitochondrial complex I in Caenorhabditis elegansGenome Analysis of Structure-Function Relationships in Respiratory Complex I, an Ancient Bioenergetic EnzymeArchitecture of complex I and its implications for electron transfer and proton pumping.Mammalian NADH:ubiquinone oxidoreductase (Complex I) and nicotinamide nucleotide transhydrogenase (Nnt) together regulate the mitochondrial production of H₂O₂--implications for their role in disease, especially cancer.Characterisation of the active/de-active transition of mitochondrial complex I.On the mechanism of respiratory complex I.Oxygen sensing by the carotid body: mechanisms and role in adaptation to hypoxia.Redox signaling in acute oxygen sensing.Mössbauer spectroscopy on respiratory complex I: the iron-sulfur cluster ensemble in the NADH-reduced enzyme is partially oxidized.Pivotal roles of three conserved carboxyl residues of the NuoC (30k) segment in the structural integrity of proton-translocating NADH-quinone oxidoreductase from Escherichia coli.Conserved amino acid residues of the NuoD segment important for structure and function of Escherichia coli NDH-1 (complex I).ND3 and ND4L subunits of mitochondrial complex I, both nucleus encoded in Chlamydomonas reinhardtii, are required for activity and assembly of the enzyme.Disruption of iron-sulphur cluster N2 from NADH: ubiquinone oxidoreductase by site-directed mutagenesis.Direct interaction between a membrane domain subunit and a connector subunit in the H(+)-translocating NADH-quinone oxidoreductase.Analysis of the subunit composition of complex I from bovine heart mitochondria.A mutation in mitochondrial complex I increases ethanol sensitivity in Caenorhabditis elegans.Functional implications from an unexpected position of the 49-kDa subunit of NADH:ubiquinone oxidoreductase.Two aspartic acid residues in the PSST-homologous NUKM subunit of complex I from Yarrowia lipolytica are essential for catalytic activity.Iron-sulfur cluster N2 of the Escherichia coli NADH:ubiquinone oxidoreductase (complex I) is located on subunit NuoB.Functional significance of conserved histidines and arginines in the 49-kDa subunit of mitochondrial complex I.Histidine 129 in the 75-kDa subunit of mitochondrial complex I from Yarrowia lipolytica is not a ligand for [Fe4S4] cluster N5 but is required for catalytic activity.Exploring the Ubiquinone Binding Cavity of Respiratory Complex IThe Redox-Bohr Group Associated with Iron-Sulfur Cluster N2 of Complex I
P2860
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P2860
A central functional role for the 49-kDa subunit within the catalytic core of mitochondrial complex I.
description
2001 nî lūn-bûn
@nan
2001年の論文
@ja
2001年学术文章
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2001年学术文章
@zh-cn
2001年学术文章
@zh-hans
2001年学术文章
@zh-my
2001年学术文章
@zh-sg
2001年學術文章
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name
A central functional role for ...... re of mitochondrial complex I.
@en
A central functional role for ...... re of mitochondrial complex I.
@nl
type
label
A central functional role for ...... re of mitochondrial complex I.
@en
A central functional role for ...... re of mitochondrial complex I.
@nl
prefLabel
A central functional role for ...... re of mitochondrial complex I.
@en
A central functional role for ...... re of mitochondrial complex I.
@nl
P2093
P2860
P356
P1476
A central functional role for ...... re of mitochondrial complex I.
@en
P2093
Kashani-Poor N
Kerscher S
P2860
P304
24082-24087
P356
10.1074/JBC.M102296200
P407
P577
2001-05-07T00:00:00Z