A role for highly conserved carboxylate, aspartate-140, in oxygen activation and heme degradation by heme oxygenase-1.
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Involvement of NADPH in the interaction between heme oxygenase-1 and cytochrome P450 reductaseComparison of apo- and heme-bound crystal structures of a truncated human heme oxygenase-2Crystal structure of rat heme oxygenase-1 in complex with heme bound to azide. Implication for regiospecific hydroxylation of heme at the alpha-meso carbonComparison of the heme-free and -bound crystal structures of human heme oxygenase-1Crystal structure of rat heme oxygenase-1 in complex with biliverdin-iron chelate. Conformational change of the distal helix during the heme cleavage reactionThe crystal structures of the ferric and ferrous forms of the heme complex of HmuO, a heme oxygenase of Corynebacterium diphtheriaeCrystal structure of the dioxygen-bound heme oxygenase from Corynebacterium diphtheriae: implications for heme oxygenase functionThe reactions of heme- and verdoheme-heme oxygenase-1 complexes with FMN-depleted NADPH-cytochrome P450 reductase. Electrons required for verdoheme oxidation can be transferred through a pathway not involving FMNSolution 1H NMR investigation of the active site molecular and electronic structures of substrate-bound, cyanide-inhibited HmuO, a bacterial heme oxygenase from Corynebacterium diphtheriae.Modulation of the axial water hydrogen-bonding properties by chemical modification of the substrate in resting state, substrate-bound heme oxygenase from Neisseria meningitidis; coupling to the distal H-bond network via ordered water molecules.Coupling of the distal hydrogen bond network to the exogenous ligand in substrate-bound, resting state human heme oxygenase.Spectroscopic insights into axial ligation and active-site H-bonding in substrate-bound human heme oxygenase-2.Solution 1H NMR characterization of substrate-free C. diphtheriae heme oxygenase: pertinence for determining magnetic axes in paramagnetic substrate complexesThe role of copper and protons in heme-copper oxidases: kinetic study of an engineered heme-copper center in myoglobin.Alteration of the regiospecificity of human heme oxygenase-1 by unseating of the heme but not disruption of the distal hydrogen bonding networkThe orbital ground state of the azide-substrate complex of human heme oxygenase is an indicator of distal H-bonding: implications for the enzyme mechanism.One heme, diverse functions: using biosynthetic myoglobin models to gain insights into heme-copper oxidases and nitric oxide reductases.1H NMR study of the effect of variable ligand on heme oxygenase electronic and molecular structure.How to Increase Brightness of Near-Infrared Fluorescent Proteins in Mammalian Cells.Reaction intermediates in the heme degradation reaction by HutZ from Vibrio cholerae.Metalloprotein and metallo-DNA/RNAzyme design: current approaches, success measures, and future challenges.Heme utilization by pathogenic bacteria: not all pathways lead to biliverdin.Crystal structure of heme oxygenase-1 from cyanobacterium Synechocystis sp. PCC 6803 in complex with heme.Unique features of recombinant heme oxygenase of Drosophila melanogaster compared with those of other heme oxygenases studied.Roles of distal Asp in heme oxygenase from Corynebacterium diphtheriae, HmuO: A water-driven oxygen activation mechanism.Protein expressed by the ho2 gene of the cyanobacterium Synechocystis sp. PCC 6803 is a true heme oxygenase. Properties of the heme and enzyme complex.O(2)- and H(2)O(2)-dependent verdoheme degradation by heme oxygenase: reaction mechanisms and potential physiological roles of the dual pathway degradation.Iron chelators inhibit the heme-degradation reaction by HutZ from Vibrio cholerae.Cryogenic absorption spectra of hydroperoxo-ferric heme oxygenase, the active intermediate of enzymatic heme oxygenationHydrogen sulfide bypasses the rate-limiting oxygen activation of heme oxygenase
P2860
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P2860
A role for highly conserved carboxylate, aspartate-140, in oxygen activation and heme degradation by heme oxygenase-1.
description
2001 nî lūn-bûn
@nan
2001年の論文
@ja
2001年学术文章
@wuu
2001年学术文章
@zh
2001年学术文章
@zh-cn
2001年学术文章
@zh-hans
2001年学术文章
@zh-my
2001年学术文章
@zh-sg
2001年學術文章
@yue
2001年學術文章
@zh-hant
name
A role for highly conserved ca ...... gradation by heme oxygenase-1.
@en
A role for highly conserved ca ...... gradation by heme oxygenase-1.
@nl
type
label
A role for highly conserved ca ...... gradation by heme oxygenase-1.
@en
A role for highly conserved ca ...... gradation by heme oxygenase-1.
@nl
prefLabel
A role for highly conserved ca ...... gradation by heme oxygenase-1.
@en
A role for highly conserved ca ...... gradation by heme oxygenase-1.
@nl
P2093
P356
P1476
A role for highly conserved ca ...... gradation by heme oxygenase-1.
@en
P2093
P304
P356
10.1021/JA010490A
P407
P577
2001-07-01T00:00:00Z