Overexpression of cytochrome P450 CYP2J2 protects against hypoxia-reoxygenation injury in cultured bovine aortic endothelial cells.
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Role of activator protein-1 in the down-regulation of the human CYP2J2 gene in hypoxiaMechanism of the sex difference in endothelial dysfunction after strokeSoluble epoxide hydrolase inhibitors and heart failureEndothelial CYP epoxygenase overexpression and soluble epoxide hydrolase disruption attenuate acute vascular inflammatory responses in micePossible role of Epoxyeicosatrienoic acid in prevention of oxidative stress mediated neuroinflammation in Parkinson disordersSoluble Epoxide Hydrolase Inhibition: Targeting Multiple Mechanisms of Ischemic Brain Injury with a Single AgentEndothelial expression of human cytochrome P450 epoxygenase CYP2C8 increases susceptibility to ischemia-reperfusion injury in isolated mouse heartAdenosine A2A receptor modulates vascular response in soluble epoxide hydrolase-null mice through CYP-epoxygenases and PPARγCytochrome P450 epoxygenases, soluble epoxide hydrolase, and the regulation of cardiovascular inflammationCytochrome P450 eicosanoids and cerebral vascular functionEpoxides and soluble epoxide hydrolase in cardiovascular physiologyRole of soluble epoxide hydrolase in postischemic recovery of heart contractile functionRole of epoxyeicosatrienoic acids in protecting the myocardium following ischemia/reperfusion injuryRenal Ischemia/Reperfusion Injury in Soluble Epoxide Hydrolase-Deficient MiceReduction of ischemia and reperfusion-induced myocardial damage by cytochrome P450 inhibitors.Mechanism of protection by soluble epoxide hydrolase inhibition in type 2 diabetic strokeIncorporation of piperazino functionality into 1,3-disubstituted urea as the tertiary pharmacophore affording potent inhibitors of soluble epoxide hydrolase with improved pharmacokinetic properties.Impaired transactivation of the human CYP2J2 arachidonic acid epoxygenase gene in HepG2 cells subjected to nitrative stress.Endogenous epoxygenases are modulators of monocyte/macrophage activityStructure-based optimization of the piperazino-containing 1,3-disubstituted ureas affording sub-nanomolar inhibitors of soluble epoxide hydrolase.Soluble epoxide hydrolase gene deletion improves blood flow and reduces infarct size after cerebral ischemia in reproductively senescent female mice.Deletion of the murine cytochrome P450 Cyp2j locus by fused BAC-mediated recombination identifies a role for Cyp2j in the pulmonary vascular response to hypoxiaEpoxyeicosatrienoic acids protect rat hearts against tumor necrosis factor-α-induced injury.Inhibition of smooth muscle proliferation by urea-based alkanoic acids via peroxisome proliferator-activated receptor alpha-dependent repression of cyclin D1.CYP2C29 produces superoxide in response to shear stress.Soluble epoxide hydrolase: sex differences and role in endothelial cell survival.Structure-activity relationships of cycloalkylamide derivatives as inhibitors of the soluble epoxide hydrolase.Cytochrome P450 subfamily 2J polypeptide 2 expression and circulating epoxyeicosatrienoic metabolites in preeclampsia.Cytochrome P450 (CYP) 2J2 gene transfection attenuates MMP-9 via inhibition of NF-kappabeta in hyperhomocysteinemiaUnusual regioselectivity and active site topology of human cytochrome P450 2J2Roles of the epoxygenase CYP2J2 in the endothelium.Novel orally active epoxyeicosatrienoic acid (EET) analogs attenuate cisplatin nephrotoxicity.Soluble epoxide inhibition is protective against cerebral ischemia via vascular and neural protection.Role of soluble epoxide hydrolase in exacerbation of stroke by streptozotocin-induced type 1 diabetes mellitus.Detection of human CYP2C8, CYP2C9, and CYP2J2 in cardiovascular tissues.Differential effects of soluble epoxide hydrolase inhibition and CYP2J2 overexpression on postischemic cardiac function in aged mice.Characterization of a c-Jun-responsive module in the 5'-flank of the human CYP2J2 gene that regulates transactivationMultiple antiapoptotic targets of the PI3K/Akt survival pathway are activated by epoxyeicosatrienoic acids to protect cardiomyocytes from hypoxia/anoxia.Soluble epoxide hydrolase inhibition Promotes White Matter Integrity and Long-Term Functional Recovery after chronic hypoperfusion in miceMeta-analysis of the association of the CYP2J2 G-50T polymorphism with coronary artery disease
P2860
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P2860
Overexpression of cytochrome P450 CYP2J2 protects against hypoxia-reoxygenation injury in cultured bovine aortic endothelial cells.
description
2001 nî lūn-bûn
@nan
2001年の論文
@ja
2001年学术文章
@wuu
2001年学术文章
@zh
2001年学术文章
@zh-cn
2001年学术文章
@zh-hans
2001年学术文章
@zh-my
2001年学术文章
@zh-sg
2001年學術文章
@yue
2001年學術文章
@zh-hant
name
Overexpression of cytochrome P ...... vine aortic endothelial cells.
@en
Overexpression of cytochrome P ...... vine aortic endothelial cells.
@nl
type
label
Overexpression of cytochrome P ...... vine aortic endothelial cells.
@en
Overexpression of cytochrome P ...... vine aortic endothelial cells.
@nl
prefLabel
Overexpression of cytochrome P ...... vine aortic endothelial cells.
@en
Overexpression of cytochrome P ...... vine aortic endothelial cells.
@nl
P2093
P921
P1476
Overexpression of cytochrome P ...... vine aortic endothelial cells.
@en
P2093
P304
P577
2001-08-01T00:00:00Z