Addition of lithiated 9-deazapurine derivatives to a carbohydrate cyclic imine: convergent synthesis of the aza-C-nucleoside immucillins.

Addition of lithiated 9-deazapurine derivatives to a carbohydrate cyclic imine: convergent synthesis of the aza-C-nucleoside immucillins.

Item
http://www.wikidata.org/entity/Q43711599
Enzymatic transition states, transition-state analogs, dynamics, thermodynamics, and lifetimesFour generations of transition-state analogues for human purine nucleoside phosphorylase.A proof-of-principle pharmacokinetic, pharmacodynamic, and clinical study with purine nucleoside phosphorylase inhibitor immucillin-H (BCX-1777, forodesine)Antiproliferative activities of halogenated thieno[3,2-d]pyrimidinesTransition state analogue inhibitors of human methylthioadenosine phosphorylase and bacterial methylthioadenosine/S-adenosylhomocysteine nucleosidase incorporating acyclic ribooxacarbenium ion mimicsEnzymatic transition state theory and transition state analogue design.Antiproliferative activities of halogenated pyrrolo[3,2-d]pyrimidinesSynthesis of the new ring system bispyrido[4',3':4,5]pyrrolo [1,2-a:1',2'-d]pyrazine and its deaza analogue.Synthesis of 2'-deoxy-9-deaza nucleosides using Heck methodology.Direct synthesis of imino-C-nucleoside analogues and other biologically active iminosugars.Immucillins in custom catalytic-site cavities.Plasmodium falciparum purine nucleoside phosphorylase: crystal structures, immucillin inhibitors, and dual catalytic function.Synthesis and pharmacokinetic and pharmacodynamic evaluation of the forodesine HCl analog BCX-3040.Intracellular rebinding of transition-state analogues provides extended in vivo inhibition lifetimes on human purine nucleoside phosphorylase.
P2860

Addition of lithiated 9-deazapurine derivatives to a carbohydrate cyclic imine: convergent synthesis of the aza-C-nucleoside immucillins.

Item
http://www.wikidata.org/entity/Q43711599
description
2001 nî lūn-bûn
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2001年の論文
@ja
2001年学术文章
@wuu
2001年学术文章
@zh
2001年学术文章
@zh-cn
2001年学术文章
@zh-hans
2001年学术文章
@zh-my
2001年学术文章
@zh-sg
2001年學術文章
@yue
2001年學術文章
@zh-hant
name
Addition of lithiated 9-deazap ...... aza-C-nucleoside immucillins.
@en
Addition of lithiated 9-deazap ...... aza-C-nucleoside immucillins.
@nl
type
label
Addition of lithiated 9-deazap ...... aza-C-nucleoside immucillins.
@en
Addition of lithiated 9-deazap ...... aza-C-nucleoside immucillins.
@nl
prefLabel
Addition of lithiated 9-deazap ...... aza-C-nucleoside immucillins.
@en
Addition of lithiated 9-deazap ...... aza-C-nucleoside immucillins.
@nl
P1433
P1476
P2093
P304
P31
P356
P407
P433
P478
P50
P577
P698
P356
P1433
P1476
Addition of lithiated 9-deazap ...... aza-C-nucleoside immucillins.
@en
P2093
P304
P31
P356
P407
P433
P478
P50
P577
P698