Thapsigargin and dimethyl sulfoxide activate medium P(i)<-->HOH oxygen exchange catalyzed by sarcoplasmic reticulum Ca2+-ATPase.
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Critical Roles of Hydrophobicity and Orientation of Side Chains for Inactivation of Sarcoplasmic Reticulum Ca2+-ATPase with Thapsigargin and Thapsigargin AnalogsGlutamate-183 in the conserved TGES motif of domain A of sarcoplasmic reticulum Ca2+-ATPase assists in catalysis of E2/E2P partial reactions.Membrane Perturbation of ADP-insensitive Phosphoenzyme of Ca2+-ATPase Modifies Gathering of Transmembrane Helix M2 with Cytoplasmic Domains and Luminal Gating.Stable structural analog of Ca2+-ATPase ADP-insensitive phosphoenzyme with occluded Ca2+ formed by elongation of A-domain/M1'-linker and beryllium fluoride binding.Remarkable stability of solubilized and delipidated sarcoplasmic reticulum Ca2+-ATPase with tightly bound fluoride and magnesium against detergent-induced denaturation.Distinct natures of beryllium fluoride-bound, aluminum fluoride-bound, and magnesium fluoride-bound stable analogues of an ADP-insensitive phosphoenzyme intermediate of sarcoplasmic reticulum Ca2+-ATPase: changes in catalytic and transport sites durStructural studies of a stabilized phosphoenzyme intermediate of Ca2+-ATPase.Evidence calcium pump binds magnesium before inorganic phosphate.Effects of inhibitors on luminal opening of Ca2+ binding sites in an E2P-like complex of sarcoplasmic reticulum Ca22+-ATPase with Be22+-fluoride.
P2860
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P2860
Thapsigargin and dimethyl sulfoxide activate medium P(i)<-->HOH oxygen exchange catalyzed by sarcoplasmic reticulum Ca2+-ATPase.
description
2001 nî lūn-bûn
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2001年の論文
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2001年学术文章
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2001年学术文章
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2001年学术文章
@zh-hans
2001年学术文章
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2001年学术文章
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2001年學術文章
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2001年學術文章
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name
Thapsigargin and dimethyl sulfoxide activate medium P
@nl
Thapsigargin and dimethyl sulf ...... plasmic reticulum Ca2+-ATPase.
@en
type
label
Thapsigargin and dimethyl sulfoxide activate medium P
@nl
Thapsigargin and dimethyl sulf ...... plasmic reticulum Ca2+-ATPase.
@en
prefLabel
Thapsigargin and dimethyl sulfoxide activate medium P
@nl
Thapsigargin and dimethyl sulf ...... plasmic reticulum Ca2+-ATPase.
@en
P2093
P2860
P356
P1476
Thapsigargin and dimethyl sulf ...... plasmic reticulum Ca2+-ATPase.
@en
P2093
P2860
P304
46737-46744
P356
10.1074/JBC.M106320200
P407
P577
2001-10-10T00:00:00Z