Death-associated protein (DAP) kinase plays a central role in ceramide-induced apoptosis in cultured hippocampal neurons. - Wikidata - awgldk - TriplyDB

Death-associated protein (DAP) kinase plays a central role in ceramide-induced apoptosis in cultured hippocampal neurons.

Death-associated protein (DAP) kinase plays a central role in ceramide-induced apoptosis in cultured hippocampal neurons.

http://www.wikidata.org/entity/Q43800114

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The Cullin 3 substrate adaptor KLHL20 mediates DAPK ubiquitination to control interferon responses Bidirectional signals transduced by DAPK-ERK interaction promote the apoptotic effect of DAPK DAP-kinase induces apoptosis by suppressing integrin activity and disrupting matrix survival signals DAP kinase and DRP-1 mediate membrane blebbing and the formation of autophagic vesicles during programmed cell death Death Associated Protein Kinase 1 (DAPK1): A Regulator of Apoptosis and Autophagy Cul3-KLHL20 ubiquitin ligase: physiological functions, stress responses, and disease implications The tumor suppressor DAPK inhibits cell motility by blocking the integrin-mediated polarity pathway.Trichostatin A sensitizes cisplatin-resistant A549 cells to apoptosis by up-regulating death-associated protein kinase Control of death-associated protein kinase (DAPK) activity by phosphorylation and proteasomal degradation Protection of FK506 against neuronal apoptosis and axonal injury following experimental diffuse axonal injury.Protein phosphatase 2A (PP2A) holoenzymes regulate death-associated protein kinase (DAPK) in ceramide-induced anoikis.Overlapping roles of Drosophila Drak and Rok kinases in epithelial tissue morphogenesis Regulation of autophagy by sphingosine kinase 1 and its role in cell survival during nutrient starvation.Effect of shear stress and substrate on endothelial DAPK expression, caspase activity, and apoptosis.Effect of DAPK1 gene on proliferation, migration, and invasion of carcinoma of pancreas BxPC-3 cell line.Structural and functional characterization of the recombinant death domain from death-associated protein kinase.Acid sphingomyelinase deficiency increases susceptibility to fatal alphavirus encephalomyelitis.Death-associated protein kinase phosphorylates mammalian ribosomal protein S6 and reduces protein synthesis Shear stress attenuates apoptosis due to TNFα, oxidative stress, and serum depletion via death-associated protein kinase (DAPK) expression.Recent advances in the immunobiology of ceramide.Death-associated protein kinase 1 phosphorylates NDRG2 and induces neuronal cell death.Critical role for transcription factor C/EBP-beta in regulating the expression of death-associated protein kinase 1.Demethylation restores SN38 sensitivity in cells with acquired resistance to SN38 derived from human cervical squamous cancer cells Fatty acid synthase is a novel therapeutic target in multiple myeloma.Synaptic dysfunction in human immunodeficiency virus type-1-positive subjects: inflammation or impaired neuronal plasticity?Ceramide and neurodegeneration: susceptibility of neurons and oligodendrocytes to cell damage and death.Dual promoter regulation of death-associated protein kinase gene leads to differentially silenced transcripts by methylation in cancer.The role of DAPK-BimEL pathway in neuronal death induced by oxygen-glucose deprivation.Role and mechanism of action of leucine-rich repeat kinase 1 in bone.Role of DAPK in neuronal cell death.DAP-kinase and autophagy.Evaluating DAPK as a therapeutic target.Actin regulation by tropomodulin and tropomyosin in neuronal morphogenesis and function.DAPK1 Signaling Pathways in Stroke: from Mechanisms to Therapies Ceramide participates in lysosome-mediated cell death induced by type II anti-CD20 monoclonal antibodies.DAP-kinase is a mediator of endoplasmic reticulum stress-induced caspase activation and autophagic cell death.A high throughput proteomics screen identifies novel substrates of death-associated protein kinase.DAPK1 Mediates LTD by Making CaMKII/GluN2B Binding LTP Specific.Endothelial apoptosis induced by inhibition of integrins alphavbeta3 and alphavbeta5 involves ceramide metabolic pathways.Upregulation of DAPK contributes to homocysteine-induced endothelial apoptosis via the modulation of Bcl2/Bax and activation of caspase 3.

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P2860

Death-associated protein (DAP) kinase plays a central role in ceramide-induced apoptosis in cultured hippocampal neurons.

http://www.wikidata.org/entity/Q43800114

description

2001 nî lūn-bûn

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2001年の論文

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2001年学术文章

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2001年学术文章

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2001年学术文章

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2001年学术文章

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2001年学术文章

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2001年学术文章

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2001年學術文章

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2001年學術文章

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name

Death-associated protein (DAP) ...... cultured hippocampal neurons.

@en

Death-associated protein

@nl

type

label

Death-associated protein (DAP) ...... cultured hippocampal neurons.

@en

Death-associated protein

@nl

prefLabel

Death-associated protein (DAP) ...... cultured hippocampal neurons.

@en

Death-associated protein

@nl

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P1433

Journal of Biological Chemistry

P1476

Death-associated protein (DAP) ...... cultured hippocampal neurons.

@en

P2093

Adi Kimchi

http://www.w3.org/2001/XMLSchema#string

Hanna Berissi

http://www.w3.org/2001/XMLSchema#string

Mati Fridkin

http://www.w3.org/2001/XMLSchema#string

Tal Raveh

http://www.w3.org/2001/XMLSchema#string

P2860

Identification of a novel serine/threonine kinase and a novel 15-kD protein as potential mediators of the gamma interferon-induced cell death

Protein kinase catalytic domain sequence database: identification of conserved features of primary structure and classification of family members

Optimized survival of hippocampal neurons in B27-supplemented Neurobasal, a new serum-free medium combination

A functional genetic screen identifies regions at the C-terminal tail and death-domain of death-associated protein kinase that are critical for its proapoptotic activity.

Ceramide in the eukaryotic stress response.

Ceramide as a second messenger: sticky solutions to sticky problems.

Apoptosis in the nervous system.

The pro-apoptotic function of death-associated protein kinase is controlled by a unique inhibitory autophosphorylation-based mechanism.

DAP-kinase: from functional gene cloning to establishment of its role in apoptosis and cancer.

DAP kinase activates a p19ARF/p53-mediated apoptotic checkpoint to suppress oncogenic transformation.

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1957-1961

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scholarly article

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10.1074/JBC.M104677200

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3

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P478

277

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Anthony H. Futerman

Christian Riebeling

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2001-11-14T00:00:00Z

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11709549

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