PPAR-alpha-null mice are protected from high-fat diet-induced insulin resistance.
about
Sorting out the roles of PPAR alpha in energy metabolism and vascular homeostasisDefective fatty acid uptake modulates insulin responsiveness and metabolic responses to diet in CD36-null miceMetabolic syndrome and type 2 diabetes mellitus: focus on peroxisome proliferator activated receptors (PPAR)Transcriptional regulation of lipid metabolism by fatty acids: a key determinant of pancreatic beta-cell functionRapid inhibition of pyruvate dehydrogenase: an initiating event in high dietary fat-induced loss of metabolic flexibility in the heartExposure to bisphenol-A during pregnancy partially mimics the effects of a high-fat diet altering glucose homeostasis and gene expression in adult male micePPARalpha governs glycerol metabolismDistinct transcriptional regulation of long-chain acyl-CoA synthetase isoforms and cytosolic thioesterase 1 in the rodent heart by fatty acids and insulinA PPARα promoter variant impairs ERR-dependent transactivation and decreases mortality after acute coronary ischemia in patients with diabetesEffects of PPARalpha on cardiac glucose metabolism: a transcriptional equivalent of the glucose-fatty acid cycle?Endocrine disrupting chemicals in mixture and obesity, diabetes and related metabolic disorders.PPAR alpha inhibits vascular smooth muscle cell proliferation underlying intimal hyperplasia by inducing the tumor suppressor p16INK4a.The role of the small intestine in the development of dietary fat-induced obesity and insulin resistance in C57BL/6J mice.Bofutsushosan, a Japanese herbal (Kampo) medicine, attenuates progression of nonalcoholic steatohepatitis in mice.Advantages of dynamic "closed loop" stable isotope flux phenotyping over static "open loop" clamps in detecting silent genetic and dietary phenotypes.PPARα-independent actions of omega-3 PUFAs contribute to their beneficial effects on adiposity and glucose homeostasisIdentification of Differentially Expressed Micrornas Associate with Glucose Metabolism in Different Organs of Blunt Snout Bream (Megalobrama amblycephala)A model of insulin resistance in mice, born to diabetic pregnancy, is associated with alterations of transcription-related genes in pancreas and epididymal adipose tissueAnorexia nervosa: a unified neurological perspectiveEffect of bezafibrate on incidence of type 2 diabetes mellitus in obese patients.Diminished hepatic gluconeogenesis via defects in tricarboxylic acid cycle flux in peroxisome proliferator-activated receptor gamma coactivator-1alpha (PGC-1alpha)-deficient mice.Peroxisome proliferator-activated receptor (PPAR) gene profiling uncovers insulin-like growth factor-1 as a PPARalpha target gene in cardioprotection.Key issues in the role of peroxisome proliferator-activated receptor agonism and cell signaling in trichloroethylene toxicity.PPAR-alpha effects on the heart and other vascular tissues.Transcriptional and phenotypic comparisons of Ppara knockout and siRNA knockdown miceWhy does starvation make bones fat?Inhibition of gluconeogenic genes by calcium-regulated heat-stable protein 1 via repression of peroxisome proliferator-activated receptor α.Genetic manipulations of PPARs: effects on obesity and metabolic disease.Aryl hydrocarbon receptor deficiency enhances insulin sensitivity and reduces PPAR-α pathway activity in mice.Lipid-induced mitochondrial stress and insulin action in muscleProtection from Metabolic Dysregulation, Obesity, and Atherosclerosis by Citrus Flavonoids: Activation of Hepatic PGC1α-Mediated Fatty Acid Oxidation.Characterization of the Mouse and Human Monoacylglycerol O-Acyltransferase 1 (Mogat1) Promoter in Human Kidney Proximal Tubule and Rat Liver Cells.The PPAR genes, cardiovascular disease and the emergence of PPAR pharmacogenetics.PPAR Genomics and Pharmacogenomics: Implications for Cardiovascular Disease.Selective PPAR modulators, dual and pan PPAR agonists: multimodal drugs for the treatment of type 2 diabetes and atherosclerosis.PPARs in Calorie Restricted and Genetically Long-Lived Mice.Pharmacogenetics of the PPAR genes and cardiovascular disease.Interferon regulatory factor 9 protects against hepatic insulin resistance and steatosis in male miceHepatic triacylglycerol accumulation and insulin resistance.Nonalcoholic Fatty liver: a possible new target for type 2 diabetes prevention and treatment.
P2860
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P2860
PPAR-alpha-null mice are protected from high-fat diet-induced insulin resistance.
description
2001 nî lūn-bûn
@nan
2001年の論文
@ja
2001年学术文章
@wuu
2001年学术文章
@zh
2001年学术文章
@zh-cn
2001年学术文章
@zh-hans
2001年学术文章
@zh-my
2001年学术文章
@zh-sg
2001年學術文章
@yue
2001年學術文章
@zh-hant
name
PPAR-alpha-null mice are protected from high-fat diet-induced insulin resistance.
@en
PPAR-alpha-null mice are protected from high-fat diet-induced insulin resistance.
@nl
type
label
PPAR-alpha-null mice are protected from high-fat diet-induced insulin resistance.
@en
PPAR-alpha-null mice are protected from high-fat diet-induced insulin resistance.
@nl
prefLabel
PPAR-alpha-null mice are protected from high-fat diet-induced insulin resistance.
@en
PPAR-alpha-null mice are protected from high-fat diet-induced insulin resistance.
@nl
P2093
P1433
P1476
PPAR-alpha-null mice are protected from high-fat diet-induced insulin resistance.
@en
P2093
Fruchart JC
Gonzalez FJ
Guerre-Millo M
P304
P356
10.2337/DIABETES.50.12.2809
P407
P50
P577
2001-12-01T00:00:00Z