Divergent TLR7 and TLR9 signaling and type I interferon production distinguish pathogenic and nonpathogenic AIDS virus infections. - Wikidata - awgldk - TriplyDB

Divergent TLR7 and TLR9 signaling and type I interferon production distinguish pathogenic and nonpathogenic AIDS virus infections.

Divergent TLR7 and TLR9 signaling and type I interferon production distinguish pathogenic and nonpathogenic AIDS virus infections.

http://www.wikidata.org/entity/Q43814365

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Generalized immune activation as a direct result of activated CD4+ T cell killing Toward an AIDS vaccine: lessons from natural simian immunodeficiency virus infections of African nonhuman primate hosts The biased nucleotide composition of HIV-1 triggers type I interferon response and correlates with subtype D increased pathogenicity The Curious Case of Type I IFN and MxA: Tipping the Immune Balance in AIDS Nonpathogenic simian immunodeficiency virus infections Epstein-Barr virus-driven lymphomagenesis in the context of human immunodeficiency virus type 1 infection Non-human primate dendritic cells Innate immune recognition of HIV-1 Inadequate clearance of translocated bacterial products in HIV-infected humanized mice Critical loss of the balance between Th17 and T regulatory cell populations in pathogenic SIV infection Association of TLR7 variants with AIDS-like disease and AIDS vaccine efficacy in rhesus macaques Intact type I Interferon production and IRF7 function in sooty mangabeys Blocking TLR7- and TLR9-mediated IFN-α production by plasmacytoid dendritic cells does not diminish immune activation in early SIV infection High levels of chronic immune activation in the T-cell compartments of patients coinfected with hepatitis C virus and human immunodeficiency virus type 1 and on highly active antiretroviral therapy are reverted by alpha interferon and ribavirin trea Life and death as a T lymphocyte: from immune protection to HIV pathogenesis Immune restoration after antiretroviral therapy: the pitfalls of hasty or incomplete repairs.Disease-promoting effects of type I interferons in viral, bacterial, and coinfections Negative regulation of interferon-β gene expression during acute and persistent virus infections Rapid inflammasome activation in microglia contributes to brain disease in HIV/AIDS Longitudinal expression of type I interferon responsive genes in systemic lupus erythematosus.Major depletion of plasmacytoid dendritic cells in HIV-2 infection, an attenuated form of HIV disease Influence of dendritic cells on viral pathogenicity Combined genome-wide expression profiling and targeted RNA interference in primary mouse macrophages reveals perturbation of transcriptional networks associated with interferon signalling The application of genomics to emerging zoonotic viral diseases IFN-alpha-induced upregulation of CCR5 leads to expanded HIV tropism in vivo Genome-wide mRNA expression correlates of viral control in CD4+ T-cells from HIV-1-infected individuals Paucity of CD4+ natural killer T (NKT) lymphocytes in sooty mangabeys is associated with lack of NKT cell depletion after SIV infection.Plasmacytoid dendritic cells accumulate and secrete interferon alpha in lymph nodes of HIV-1 patients.Positive selection of HIV host factors and the evolution of lentivirus genes Sex differences in the Toll-like receptor-mediated response of plasmacytoid dendritic cells to HIV-1.Pathogenic potential of interferon αβ in acute influenza infection Damaged intestinal epithelial integrity linked to microbial translocation in pathogenic simian immunodeficiency virus infections.Similar impact of CD8+ T cell responses on early virus dynamics during SIV infections of rhesus macaques and sooty mangabeys.Pathophysiology of CD4+ T-Cell Depletion in HIV-1 and HIV-2 Infections Host genetics and HIV-1: the final phase?Early myeloid dendritic cell dysregulation is predictive of disease progression in simian immunodeficiency virus infection Plasmacytoid dendritic cells in HIV infection: striking a delicate balance.Differential inhibition of human immunodeficiency virus type 1 in peripheral blood mononuclear cells and TZM-bl cells by endotoxin-mediated chemokine and gamma interferon production.Low CD4+ T cell counts among African HIV-1 infected subjects with group B KIR haplotypes in the absence of specific inhibitory KIR ligands.Partial regulatory T cell depletion prior to acute feline immunodeficiency virus infection does not alter disease pathogenesis

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Divergent TLR7 and TLR9 signaling and type I interferon production distinguish pathogenic and nonpathogenic AIDS virus infections.

http://www.wikidata.org/entity/Q43814365

description

2008 nî lūn-bûn

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2008年の論文

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2008年学术文章

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2008年学术文章

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2008年学术文章

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2008年学术文章

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2008年學術文章

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2008年學術文章

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name

Divergent TLR7 and TLR9 signal ...... hogenic AIDS virus infections.

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Divergent TLR7 and TLR9 signal ...... hogenic AIDS virus infections.

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type

label

Divergent TLR7 and TLR9 signal ...... hogenic AIDS virus infections.

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Divergent TLR7 and TLR9 signal ...... hogenic AIDS virus infections.

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prefLabel

Divergent TLR7 and TLR9 signal ...... hogenic AIDS virus infections.

@en

Divergent TLR7 and TLR9 signal ...... hogenic AIDS virus infections.

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Nature Medicine

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Divergent TLR7 and TLR9 signal ...... hogenic AIDS virus infections.

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P2093

Ashley P Barry

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Franck J Barrat

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Judith N Mandl

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Mark B Feinberg

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Natalia Kozyr

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Rahul Chavan

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Robert L Coffman

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Sara Klucking

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Silvija I Staprans

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Thomas H Vanderford

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1077-1087

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10.1038/NM.1871

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10

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23270141

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18806803

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Toll-like receptor