Involvement of up-regulation of 17beta-hydroxysteroid dehydrogenase type 1 in maintenance of intratumoral high estradiol levels in postmenopausal breast cancers.
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Placental biomarkers of phthalate effects on mRNA transcription: application in epidemiologic researchQuantitative determination, by real-time reverse transcription polymerase chain reaction, of aromatase mRNA in invasive ductal carcinoma of the breastPharmacophore Models and Pharmacophore-Based Virtual Screening: Concepts and Applications Exemplified on Hydroxysteroid DehydrogenasesInsights in 17beta-HSD1 enzyme kinetics and ligand binding by dynamic motion investigationCofactor hydrogen bonding onto the protein main chain is conserved in the short chain dehydrogenase/reductase family and contributes to nicotinamide orientationBinary and ternary crystal structure analyses of a novel inhibitor with 17beta-HSD type 1: a lead compound for breast cancer therapyAndrogen Receptor: A Complex Therapeutic Target for Breast CancerTranscriptional biomarkers of steroidogenesis and trophoblast differentiation in the placenta in relation to prenatal phthalate exposureNovel hydroxysteroid (17beta) dehydrogenase 1 inhibitors reverse estrogen-induced endometrial hyperplasia in transgenic miceEstrogen and androgen-converting enzymes 17β-hydroxysteroid dehydrogenase and their involvement in cancer: with a special focus on 17β-hydroxysteroid dehydrogenase type 1, 2, and breast cancer.The contribution of 17beta-hydroxysteroid dehydrogenase type 1 to the estradiol-estrone ratio in estrogen-sensitive breast cancer cellsIrosustat: a first-generation steroid sulfatase inhibitor in breast cancer.Aromatase, estrone sulfatase, and 17β-hydroxysteroid dehydrogenase: structure-function studies and inhibitor development.Confirmation of the reduction of hormone replacement therapy-related breast cancer risk for carriers of the HSD17B1_937_G variant.The stimulation of HSD17B7 expression by estradiol provides a powerful feed-forward mechanism for estradiol biosynthesis in breast cancer cells.17beta-Hydroxysteroid dehydrogenases involved in local oestrogen synthesis have prognostic significance in breast cancer.Expression of estrogenicity genes in a lineage cell culture model of human breast cancer progression.Activation of aromatase expression by retinoic acid receptor-related orphan receptor (ROR) alpha in breast cancer cells: identification of a novel ROR response element.Regulation of 17β-hydroxysteroid dehydrogenases in cancer: regulating steroid receptor at pre-receptor stage.IPET study: an FLT-PET window study to assess the activity of the steroid sulfatase inhibitor irosustat in early breast cancer.Enzyme inhibitor screening using a homogeneous proximity-based immunoassay for estradiol.Direct antiproliferative effect of nonsteroidal 17β-hydroxysteroid dehydrogenase type 1 inhibitors in vitro.Expression of 5α-reductase type 1 in breast cancer and adjacent non-malignant tissue: an immunohistochemical study.Design and synthesis of substrate mimetics based on an indole scaffold: potential inhibitors of 17β-HSD type 1.
P2860
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P2860
Involvement of up-regulation of 17beta-hydroxysteroid dehydrogenase type 1 in maintenance of intratumoral high estradiol levels in postmenopausal breast cancers.
description
2001 nî lūn-bûn
@nan
2001年の論文
@ja
2001年学术文章
@wuu
2001年学术文章
@zh
2001年学术文章
@zh-cn
2001年学术文章
@zh-hans
2001年学术文章
@zh-my
2001年学术文章
@zh-sg
2001年學術文章
@yue
2001年學術文章
@zh-hant
name
Involvement of up-regulation o ...... postmenopausal breast cancers.
@en
Involvement of up-regulation o ...... postmenopausal breast cancers.
@nl
type
label
Involvement of up-regulation o ...... postmenopausal breast cancers.
@en
Involvement of up-regulation o ...... postmenopausal breast cancers.
@nl
prefLabel
Involvement of up-regulation o ...... postmenopausal breast cancers.
@en
Involvement of up-regulation o ...... postmenopausal breast cancers.
@nl
P2093
P2860
P356
P1476
Involvement of up-regulation o ...... postmenopausal breast cancers.
@en
P2093
P2860
P304
P356
10.1002/IJC.1525
P577
2001-12-01T00:00:00Z