Soluble recombinant neprilysin induces aggrecanase-mediated cleavage of aggrecan in cartilage explant cultures.
about
ADAMTS4 (aggrecanase-1) activation on the cell surface involves C-terminal cleavage by glycosylphosphatidyl inositol-anchored membrane type 4-matrix metalloproteinase and binding of the activated proteinase to chondroitin sulfate and heparan sulfateCartilage-specific constitutive expression of TSG-6 protein (product of tumor necrosis factor alpha-stimulated gene 6) provides a chondroprotective, but not antiinflammatory, effect in antigen-induced arthritis.
P2860
Soluble recombinant neprilysin induces aggrecanase-mediated cleavage of aggrecan in cartilage explant cultures.
description
2001 nî lūn-bûn
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2001年の論文
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2001年学术文章
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2001年学术文章
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name
Soluble recombinant neprilysin ...... in cartilage explant cultures.
@en
Soluble recombinant neprilysin ...... in cartilage explant cultures.
@nl
type
label
Soluble recombinant neprilysin ...... in cartilage explant cultures.
@en
Soluble recombinant neprilysin ...... in cartilage explant cultures.
@nl
prefLabel
Soluble recombinant neprilysin ...... in cartilage explant cultures.
@en
Soluble recombinant neprilysin ...... in cartilage explant cultures.
@nl
P2093
P356
P1476
Soluble recombinant neprilysin ...... in cartilage explant cultures.
@en
P2093
P304
P356
10.1006/ABBI.2001.2608
P407
P577
2001-12-01T00:00:00Z