Evaluation of statistical designs in phase I expansion cohorts: the Dana-Farber/Harvard Cancer Center experience.
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The European Organization for Research and Treatment of Cancer perspective on designing clinical trials with immune therapeuticsA statistical evaluation of dose expansion cohorts in phase I clinical trials.Dose expansion cohorts in Phase I trials.Combined integrated protocol/basket trial design for a first-in-human trial.Challenges of phase 1 clinical trials evaluating immune checkpoint-targeted antibodies.Response Rate as a Regulatory End Point in Single-Arm Studies of Advanced Solid Tumors.Statistical controversies in clinical research: building the bridge to phase II-efficacy estimation in dose-expansion cohorts.Evolution of early phase clinical trials in oncology.Use of Expansion Cohorts in Phase I Trials and Probability of Success in Phase II for 381 Anticancer Drugs.
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P2860
Evaluation of statistical designs in phase I expansion cohorts: the Dana-Farber/Harvard Cancer Center experience.
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Evaluation of statistical desi ...... vard Cancer Center experience.
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Evaluation of statistical desi ...... vard Cancer Center experience.
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type
label
Evaluation of statistical desi ...... vard Cancer Center experience.
@en
Evaluation of statistical desi ...... vard Cancer Center experience.
@nl
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Evaluation of statistical desi ...... vard Cancer Center experience.
@en
Evaluation of statistical desi ...... vard Cancer Center experience.
@nl
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P2860
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Evaluation of statistical desi ...... rvard Cancer Center experience
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Bruce E Johnson
Geoffrey I Shapiro
Jeffrey W Clark
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10.1093/JNCI/DJU163
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2014-06-24T00:00:00Z