Tandem function of nucleotide binding domains confers competence to sulfonylurea receptor in gating ATP-sensitive K+ channels.
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Kir6.2 is required for adaptation to stress.ABCC9 mutations identified in human dilated cardiomyopathy disrupt catalytic KATP channel gatingThe Nucleotide-Binding Sites of SUR1: A Mechanistic ModelPotassium channel regulation.Proximal C-terminal domain of sulphonylurea receptor 2A interacts with pore-forming Kir6 subunits in KATP channelsUltrasound-enhanced delivery of targeted echogenic liposomes in a novel ex vivo mouse aorta modelQuaternary structure of KATP channel SUR2A nucleotide binding domains resolved by synchrotron radiation X-ray scattering.ATP-sensitive K+ channel knockout induces cardiac proteome remodeling predictive of heart disease susceptibility.Human K(ATP) channelopathies: diseases of metabolic homeostasis.K(ATP) channels and insulin secretion disorders.Cellular remodeling in heart failure disrupts K(ATP) channel-dependent stress toleranceExercise-induced expression of cardiac ATP-sensitive potassium channels promotes action potential shortening and energy conservation.Muscle KATP channels: recent insights to energy sensing and myoprotectionAdvances in cardiac ATP-sensitive K+ channelopathies from molecules to populations.N-terminal transmembrane domain of the SUR controls trafficking and gating of Kir6 channel subunits.Reduction in number of sarcolemmal KATP channels slows cardiac action potential duration shortening under hypoxia.ATP-sensitive K+ channel channel/enzyme multimer: metabolic gating in the heart.Insight in eukaryotic ABC transporter function by mutation analysis.Role for SUR2A ED domain in allosteric coupling within the K(ATP) channel complex.Regulation of cardiac ATP-sensitive potassium channel surface expression by calcium/calmodulin-dependent protein kinase II.ATP-sensitive potassium channels: metabolic sensing and cardioprotection.KCNJ11 knockout morula re-engineered by stem cell diploid aggregation.Interaction of asymmetric ABCC9-encoded nucleotide binding domains determines KATP channel SUR2A catalytic activity.Nucleotide-gated KATP channels integrated with creatine and adenylate kinases: amplification, tuning and sensing of energetic signals in the compartmentalized cellular environment.The unusual stoichiometry of ADP activation of the KATP channel.ABCC9 is a novel Brugada and early repolarization syndrome susceptibility gene.ATP-binding cassette proteins involved in glucose and lipid homeostasis.Functional effects of naturally occurring KCNJ11 mutations causing neonatal diabetes on cloned cardiac KATP channels.The First Nucleotide Binding Domain of Cystic Fibrosis Transmembrane Conductance Regulator Is a Site of Stable Nucleotide Interaction, whereas the Second Is a Site of Rapid Turnover.The ATPase activities of sulfonylurea receptor 2A and sulfonylurea receptor 2B are influenced by the C-terminal 42 amino acids.The NBDs that wouldn't die: A cautionary tale of the use of isolated nucleotide binding domains of ABC transporters.Coupling of cell energetics with membrane metabolic sensing. Integrative signaling through creatine kinase phosphotransfer disrupted by M-CK gene knock-out.Modulation of the trafficking efficiency and functional properties of ATP-sensitive potassium channels through a single amino acid in the sulfonylurea receptor.Regulation of action potential duration under acute heat stress by I(K,ATP) and I(K1) in fish cardiac myocytes.Functional effects of KCNJ11 mutations causing neonatal diabetes: enhanced activation by MgATP.Phosphatidylinositol-4,5-bisphosphate (PIP2) regulation of strong inward rectifier Kir2.1 channels: multilevel positive cooperativity.Channelopathies: decoding disease pathogenesis.KATP channel knockout worsens myocardial calcium stress load in vivo and impairs recovery in stunned heart.Protection conferred by myocardial ATP-sensitive K+ channels in pressure overload-induced congestive heart failure revealed in KCNJ11 Kir6.2-null mutant.Aortic aneurysm and craniosynostosis in a family with Cantu syndrome
P2860
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P2860
Tandem function of nucleotide binding domains confers competence to sulfonylurea receptor in gating ATP-sensitive K+ channels.
description
2002 nî lūn-bûn
@nan
2002年の論文
@ja
2002年学术文章
@wuu
2002年学术文章
@zh
2002年学术文章
@zh-cn
2002年学术文章
@zh-hans
2002年学术文章
@zh-my
2002年学术文章
@zh-sg
2002年學術文章
@yue
2002年學術文章
@zh-hant
name
Tandem function of nucleotide ...... ing ATP-sensitive K+ channels.
@en
Tandem function of nucleotide ...... ing ATP-sensitive K+ channels.
@nl
type
label
Tandem function of nucleotide ...... ing ATP-sensitive K+ channels.
@en
Tandem function of nucleotide ...... ing ATP-sensitive K+ channels.
@nl
prefLabel
Tandem function of nucleotide ...... ing ATP-sensitive K+ channels.
@en
Tandem function of nucleotide ...... ing ATP-sensitive K+ channels.
@nl
P2093
P2860
P356
P1476
Tandem function of nucleotide ...... ting ATP-sensitive K+ channels
@en
P2093
Alexey E Alekseev
Andre Terzic
Denice M Hodgson
Eva C Kathmann
Leonid V Zingman
Martin Bienengraeber
P2860
P304
14206-14210
P356
10.1074/JBC.M109452200
P407
P577
2002-02-01T00:00:00Z